Chances and limits of polar body analysis;Moglichkeiten und grenzen der polkorperdiagnostik

Reproduktionsmedizin

Volumn 16, Issue 5, 2000, Pages 343-353

  Buchholz, T ^a   Clement Sengewald, A ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Embryo protection law; FISH; Polar body analysis; Prefertilisation diagnosis; Single cell PCR

Indexed keywords

CHROMOSOME ABERRATION; ETHICS; FERTILIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GENETIC DISORDER; HUMAN; HUMAN CELL; LAW; MATERNAL AGE; OOCYTE DEVELOPMENT; PATERNITY; POLYMERASE CHAIN REACTION; PREGNANCY; PRENATAL DIAGNOSIS; REPRODUCTION; REVIEW;

EID: 0033787448     PISSN: 14346931     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004440000208     Document Type: Review

References (67)

1. Chromosome anomalies in human oocytes in relation to age
2. The effects of age and abnormal sperm count on the nondisjunction of spermatozoa
3. Preimplantation genetic diagnosis of aneuploidy: Were we looking at the wrong chromosomes?
4. Dapi staining prior to FISH-analysis in polar bodies
5. Laser-assisted, non-contact extraction of polar bodies for preimplantation diagnosis
6. Vergleich verschiedener manipulationsmethoden zur extraktion von polkorpern
7. Implantation enhancement by selective assisted hatching using zona drilling of human embryos with poor prognosis
8. Infertile couples with Robertsonian translocations: Preimplantation genetic analysis of embryos reveals chaotic cleavage divisions
9. Association between non disjunction and maternal age in meiosis II human oocytes
10. The role of maternal age in assisted reproductive technologies
11. Chromosome studies in first polar bodies from hamster and human oocytes
12. Detection of aneuploidy in human oocytes and corresponding first polar bodies by fluorescent in situ hybridization
13. Elective transfer of embryos selected on the basis of first polar body morphology is associated with increased rates of implantation and pregnancy
14. Of course, not
15. Human male infertility: Chromosome anomalies, meiotic disorders, abnormal spermatozoa and recurrent abortion
16. ESHRE Preimplantation Genetic Diagnosis (PGD) Consortium: Preliminary assessment of data from January 1997 to September 1998
17. Preimplantation genetic diagnosis using fluoreszent polymerase chain reaction: Results and future development
18. Pronuclear orientation, polar body placement, and embryo quality after intracytoplasmatic sperm injection and in-vitro fertilization: Further evidence for polarity in human oocytes?
19. The incidence, origin, and etiology of aneuploidy
20. Recent advances and future development in PGD
21. A cytogenetic study of 1000 spontaneous abortions
22. Human aneuploidy: Incidence, origin, and etiology
23. Recycling of a single human blastomere fixed on a microscopic slide for sexing and diagnosis of specific mutations by various types of polymerase chain reaction
24. Preimplantation genetic diagnosis - An integral part of assisted reproduction
25. Reduced survival after humanembryo biopsy and subsequent cryopreservation
26. Viability of embryos following second polar body removal in a mouse model
27. Comparative genomic hybridization, loss of heterzygosity, and ONA sequence analysis of single cells
28. Pregnancy after polar body biopsy and freezing and thawing of human embryos
29. Unequal pronudear size - A powerful predictor of embryonic chromosome anormalies
30. Laser-assisted microdissection of the zona pellucida facilitates polar body biopsy
31. Gibt es Vorteile des assisted hatching?
32. Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities
33. The use of first polar bodies for preimplantation diagnosis of aneuploidy
34. First pregnancies after preconception diagnosis of translocations of maternal origin
35. Preim-plantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16, 18, 21, 22
36. Spontaneous abortions are reduced after preconception diagnosis of translocations
37. Screening for aneuploidies and translocations
38. Does preimplantation genetic diagnosis (PGD) need a new name?
39. Preliminary observations on polar body extrusionand pronudear formation in human oocytes using time-lapse video cinematography
40. In vitro fertilization plus preimplantation genetic diagnosis in patients with recurrent miscarriage: An analysis of chromosome abnormalities in human preimplantation embryos
41. Aneuploidy frequencies in semen fractions from ten oligoasthenoteratozoospermic patients donating sperm for intracytoplasmic sperm injection
42. Menschenzucht in deutschland
43. Accuracy of preimplantation diagnosis of single-gene disorders by polar body analysis of cytes
44. High incidence of chromosomal abnormalities in pre-implantation embryos from recurrent spontaneous abortin patients
45. Impaired development of zygotes with uneven pronudear size
46. Catch and move - Cut or fuse
47. Chromosome translocations: Segregation modes and strategies for preimplantation genetic diagnosis
48. Frequency of abnormal karyo-types among abortuses from women with and without a history of recurrent spontaneous abortion
49. Micromanipulation of sperm by a laser generated optical trap
50. Analysis of the first polar body: Preconception genetic diagnosis
51. Preconception and preimplantation diagnosis for cystic fibrosis
52. Embryological and technical aspects of preimplantation genetic diagnosis
53. Polar body diagnosis of common aneuploidies by FISH
54. Birth of healthy children after preimplantaion diagnosis of common aneuploidies by polar body fluorescent in situ hybridization analysis
55. Preimplantation diagnosis of common aneuploidies by the first and second polar body FISH analysis
56. Preimplantation diagnosis: An alternative to prenatal diagnosis of genetic and chromosomal disorders
57. Karyotyping of human oocytes by chromosomal analysis of the second polar bodies
58. Prepregnancy testing for single-gene disorders by polar body analysis
59. FISH preimplantation diagnosis of chromosome aneuploidy in recurrent pregnancy wastage
60. Detection of aneuploidy in single cells using comparative genomic hybridisation
61. FISH-microdissection (FISH-MD) analysis of complex chromosome rearrangements
62. Strategies for preimplanration genetic diagnosis of single gene disorders by DNA amplification
63. Detailed chromosomal and molecular genetic analysis of single cells by whole genuine amplification and comparative genomic hybridisation
64. Rapid visualization of metaphase chromosomes in single human blastomeres after fusion with in-vitro matured bovine eggs
65. Prefertilization diagnosis - A proposal for a revised nomenclature
66. Improving the fixation method for preimplantation genetic diagnosis by fluorescent in situ hybridization
67. Chromosome status of untransferred (spare) embryos and probability of pregnancy after in-vitro fertilisation