Is there an association between angiotensin-converting enzyme gene variants and chronic nonproductive cough?

Chest

Volumn 118, Issue 4, 2000, Pages 1091-1094

  McGarvey, Lorcan P A ^a   Savage, David A ^b   Feeney, Susan A ^b   Heaney, Liam G ^a   Ennis, Madeleine ^b   MacMahon, Joseph ^a   Maxwell, A Peter ^a  

^a BELFAST CITY HOSPITAL   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Angiotensin converting enzyme; Chronic cough; Polymorphism

Indexed keywords

CAPSAICIN; DIPEPTIDYL CARBOXYPEPTIDASE; DNA; GENE PRODUCT;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; CONTROLLED STUDY; COUGHING; DIAGNOSTIC PROCEDURE; DISEASE DURATION; DNA POLYMORPHISM; FEMALE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVOCATION TEST; RISK FACTOR;

EID: 0033782364     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.118.4.1091     Document Type: Article

References (21)

1. Chronic cough: The spectrum and frequency of causes, key components of the diagnostic evaluation and outcome of specific therapy
2. ACE inhibitor induced cough and bronchospasm: Incidence, mechanisms and management
3. Cough sensitivity to inhaled capsaicin decreases with successful treatment of chronic cough
4. Sensitivity of the cough reflex in patients with chronic cough
5. Bradykinin-evoked sensitization of airway sensory nerves: A mechanism for ACE-inhibitor cough
6. Evidence for substance P as an endogenous substance causing cough in guinea pigs
7. An enzyme in microsomal fraction of kidney that inactivates bradykinin
8. Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase
9. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
10. Cough and angioneurotic oedema associated with angiotensin-converting enzyme inhibitor therapy: A review of the literature and pathophysiology
11. ACE inhibitor cough: A genetic link
12. Angiotensin-I-converting enzyme gene polymorphism and susceptibility to cough
13. ACE inhibitors, cough, and genetics
14. Three candidate genes and angiotensin converting enzyme inhibitor related cough: A pharmacogenetic analysis
15. Polymorphisms of the angiotensin-converting enzyme gene in subjects who die from coronary heart disease
16. Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol
17. Bronchial reactivity to inhaled histamine: A method and clinical survey
18. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)
19. ACE gene typing
20. Single-reagent microcentrifugal assay for angiotensin-converting enzyme in serum
21. Human ACE gene polymorphism and distilled water induced cough