Three candidate genes and angiotensin-converting enzyme inhibitor- related cough: A pharmacogenetic analysis

Hypertension

Volumn 31, Issue 4, 1998, Pages 925-928

  Zee, Robert Y L ^a   Rao, Valluri S ^a   Paster, Robert Z ^c   Sweet, Charles S ^d   Lindpaintner, Klaus ^a,b,e,f  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c DEAN MEDICAL CENTER   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Angiotensin converting enzyme; Angiotensin converting enzyme inhibitors; Chymase; Cough; Genetics; Polymorphism; Receptors, bradykinin

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LISINOPRIL;

ADULT; ALLELE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DNA POLYMORPHISM; DOUBLE BLIND PROCEDURE; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0031924635     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.31.4.925     Document Type: Article

References (12)

1. SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. N Engl J Med. 1991;325:293-302.
2. Fuller RW, Choudry NB. Increased cough reflex associated with angiotensin-converting enzyme inhibitor cough. Br Med J. 1987;295: 1025-1026.
3. Bucker CE, Neilly JB, Carter R, Stevenson RD, Semple PF. Bronchial hypersensitivity in patients who cough after receiving angiotensin- converting enzyme inhibitors. Br Med J. 1988;296:880-888.
4. Yeo WW, Ramsey LE, Morice AH. ACE inhibitor cough: a genetic link. Lancet. 1991;337:187. Letter.
5. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invent. 1990;86:1343-1346.
6. Tiret L, Rigat B, Visvikis S, Breda C, Corvol P, Cambien F, Soubrier F. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet. 1992;51:197-205.
7. Mao XQ, Shirakawa T, Yoshikawa T, Yoshikawa K, Kawai M, Sasaki S, Enomoto T, Hashimoto T, Furuyama J, Hopkin JM, Morimoto K. Association between genetic variants of mast-cell chymase and eczema. Lancet. 1996;348:581-583.
8. Caughey GH, Zerweck EH, Vanderslice P. Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase. J Biol Chem. 1991;266:12956-12963.
9. Braun A, Kammerer S, Bohme E, Muller B, Roscher AA. Identification of polymorphic sites of the human bradykinin B2 receptor gene. Biochem Biophys Res Commun. 1995;211:234-240.
10. Lung CC, Chan ED, Zuraw BL. Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency. J Allergy Clin Immunol. 1997;99: 134-146.
11. Lacourciere Y, Lefebvre J, Nakhle G, Faison EP, Snavely DB, Nelson EB. Association between cough and angiotensin-converting enzyme inhibitors versus angiotensin II antagonists: the design of a prospective, controlled study. J Hypertens. 1994;12(suppl 2):49-53.
12. Lindpaintner K, Pfeffer MA, Kreutz R, Stampfer MJ, Grodstein F, LaMotte F, Buring J, Hennekens CH. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med. 1993;332:706-711.