Do infectious diseases drive MHC diversity?

Microbes and Infection

Volumn 2, Issue 11, 2000, Pages 1335-1341

  Jeffery, Katie J M ^a   Bangham, Charles R M ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Cytotoxic T lymphocyte; Genetic predisposition to disease; Infection; Major histocompatibility complex; Polymorphism; Selection; Virus

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN;

ALLELE; BIODIVERSITY; GENE CLUSTER; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENOME; IMMUNE SYSTEM; INFECTION; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; REVIEW; VIRUS PATHOGENESIS;

EID: 0033778423     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(00)01287-9     Document Type: Review

References (63)

1. Disease and evolution
2. Stealth, sabotage and exploitation
3. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
4. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
5. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
6. The immunogenetics of human infectious diseases
7. Mechanisms of MHC class I-restricted antigen processing
8. Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis
9. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
10. Capture and processing of exogenous antigens for presentation on MHC molecules
11. A biological role for the major histocompatibility antigens
12. Evolutionary rate at the molecular level
13. Natural selection on the peptide-binding regions of major histocompatibility complex molecules
14. Population biology of antigen presentation by MHC class I molecules
15. Effect of gene conversion on polymorphic patterns at major histocompatibility complex loci
16. Evolution of MHC genetic diversity: A tale of incest, pestilence and sexual preference
17. How do major histocompatibility complex genes influence odor and mating preferences?
18. Strong balancing selection at HLA loci: Evidence from segregation in South Amerindian families
19. Maintenance of histocompatibility polymorphisms
20. Human leukocyte antigen matching and fetal loss: Results of a 10 year prospective study
21. HLA and HIV-1: Heterozygote advantage and B*35-Cw*04 disadvantage
22. HLA class I homozygosity accelerates disease progression in human immunodeficiency virus type 1 infection
23. Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
24. Escape of human immunodeficiency virus from immune control
25. Emergence of virus escape mutants after immunization with epitope vaccine
26. Heterozygote advantage for HLA class-II type in hepatitis B virus infection
27. Hepatitis B virus immunopathogenesis
28. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
29. Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants
30. Association of malaria parasite population structure, HLA, and immunological antagonism
31. Immunodominance of a single CTL epitope in a primate species with limited MHC class I polymorphism
32. Monomorphism and polymorphism at Mhc DRB loci in domestic and wild ruminants
33. Virtual reality in the MHC
34. Common west African HLA antigens are associated with protection from severe malaria
35. Marek's disease: Effects of B histocompatibility alloalleles in resistant and susceptible chicken lines
36. Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D
37. The infection of mouse by Theiler's virus: From genetics to immunology
38. Association between an MHC class II allele and clearance of Heptitis B virus in the Gambia
39. Genes of the major histocompatibility complex class II influence the outcome of hepatitis C virus infection
40. Association between MHC class II alleles and clearance of circulating hepatitis C virus. Members of the Trent Hepatitis C Virus Study Group
41. Association of major histocompatibility complex determinants with the development of symptomatic and asymptomatic genital herpes simplex virus type 2 infections
42. HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy
43. Host genetic influences on HIV-1 pathogenesis
44. HIV and HLA: Confusion or complexity
45. Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia Cohort and Hemophilia Growth and Development Studies
46. HLA haplotype A1 B8 DR3 as a risk factor for HIV-related disease
47. HLA-associated susceptibility to acquired immunodeficiency syndrome in Italian patients with human-immunodeficiency-virus infection
48. A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort Study
49. Association of HLA types A1-B8-DR3 and B27 with rapid and slow progression of HIV disease
50. Combined genotypes of CCR5, CCR2, SDF1, and HLA genes can predict the long-term nonprogressor status in human immunodeficiency virus-1-infected individuals
51. Heterozygosity at individual amino acid sites: Extremely high levels for HLA-A and -B genes
52. Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci
53. Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
54. Structure of the human class I histocompatibility antigen, HLA-A2
55. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
56. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
57. Nucleotide substitution at major histocompatibility complex class II loci: Evidence for overdominant selection
58. Natural selection at the class II major histocompatibility complex loci of mammals
59. Natural selection at major histocompatibility complex loci of vertebrates
60. Quantification of the relative contribution of major histocompatibility complex (MHC) and nonMHC genes to human immune responses to foreign antigens
61. HLA-A11 epitope loss isolates of Epstein-Barr virus from a highly A11 + population