Chromosome 4 deletions are frequent in invasive cervical cancer and differ between histologic variants

Gynecologic Oncology

Volumn 79, Issue 1, 2000, Pages 90-96

  Sherwood, Jennifer B ^a,b   Shivapurkar, Narayan ^b   Lin, W Michael ^a,b   Ashfaq, Raheela ^a   Miller, David S ^a,b   Gazdar, Adi F ^a,b   Muller, Carolyn Y ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Adenocarcinoma; Allele loss; Human papillomavirus; Loss of heterozygosity; Squamous cell carcinoma

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CANCER INVASION; CANCER RISK; CHILD; CHROMOSOME DELETION 4; CHROMOSOME VARIANT; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE TARGETING; HETEROZYGOSITY LOSS; HISTOLOGY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

EID: 0033778056     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.2000.5922     Document Type: Article

References (26)

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2. Genetic alterations at 5p15: A potential marker for progression of precancerous lesions of the uterine cervix
3. Allelo-typing of all chromosomal arms in invasive cervical cancer
4. Allelic loss and microsatellite alteration of chromosome 3p14.2 are more frequent in recurrent cervical dysplasias
5. FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations
6. Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma
7. Deletions of chromosome 4 at multiple sites are frequent in malignant mesothelioma and small cell lung carcinoma
8. Multiple regions of chromosome 4 demonstrating allelic loss in breast carcinomas
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13. Molecular basis of endometrial cancer
14. Human ovarian cancer of the surface epithelium
15. Laser capture microdissection
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17. The 1993-94 genethon human genetic linkage map
18. The use of general primers GP5 and GP6 elongated at their 3' ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR
19. Comprehensive study of several general and type-specific primer pairs for detection of human papillomavirus DNA by PCR in paraffin-embedded cervical carcinomas
20. Genetic alterations accumulate during cervical tumorigenesis and indicate a common origin for mulifocal lesions
21. Allelotype analysis of cervical carcinoma
22. Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: Subregional mapping of chromosome 4 in cervical carcinoma
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24. Human papillomavirus types 16 and 18 in adenocarcinoma of the uterine cervix
25. Detection of frequent allelic loss of 6q23-q 25.2 in microdissected human breast cancer tissues
26. Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma