Galectin-1 induces central and peripheral cell death: Implications in T-cell physiopathology

Developmental Immunology

Volumn 7, Issue 2-4, 2000, Pages 117-129

  Sotomayor, C E ^a   Rabinovich, G A ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Apoptosis; Autoimmunity; Galectin 1; Immunomodulation; Macrophages

Indexed keywords

GALAPTIN; GALECTIN; GALECTIN 1; GLYCOCONJUGATE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL DEATH; CELL SURFACE; IMMUNOMODULATION; INFLAMMATORY DISEASE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; T LYMPHOCYTE;

ANIMALIA;

EID: 0033777124     PISSN: 10446672     EISSN: None     Source Type: Journal    
DOI: 10.1155/2000/36321     Document Type: Article

References (95)

1. Targeted mutation in the Fas gene cause hyperplasia in the peripheral lymphoid organs and liver
2. The Bcl-2 protein family: Arbiters of cell survival
3. The cell biology of macrophage activation
4. Biphasic modulation of cell growth by recombinant human galectin-1
5. A novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
6. Galectin-3 in Tumor metastasis
7. Do macrophages kill through apoptosis?
8. Localization of endogenous beta-galactoside-binding lectin in human cells and tissues
9. β-Galactoside-binding protein (β-GBP) alters the cell cycle, up-regulates expression of the α- and β-chains of the IFN-γ receptor, and triggers IFN-γ-mediated apoptosis of activated human T lymphocytes
10. Cellular interactions in thymocyte development
11. Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocites in vitro
12. Galectins: A familly of animal galactoside-binding lectins
13. Galectins: Structure and function of a large family of animal lectins
14. Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells
15. Synthesis of an endogenous lectin, galectin-1 by human endothelial cells is up-regulated by endothelial cell activation
16. β-Galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells
17. Cell-autonomus Fas (CD95)/Fas -ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
18. Gene therapy in rheumatoid arthritis via cytokine regulation: Future perspectives
19. Apoptosis and programmed cell death in immunity
20. Treatment of autoimmune disease: To activate or to deactivate?
21. The role of galectins in mouse development
22. Endogenous muscle lectin inhibits myoblast adhesion to laminin
23. Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism
24. Autocrine T-cell suicide mediated by APO-1 (Fas/CD95)
25. Collagen-induced arthritis as a model of rheumatoid arthritis
26. Rheumatoid Arthritis
27. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
28. Activation of transcription factor NF-kB in human synovial cells in response to tumor necrosis factor α
29. Involvement of Apo-1/Fas (CD95) receptor and ligand in liver damage
30. Isolation of a cDNA clone, encoding a human β-galactoside-binding protein overexpressed during glucocorticoid-induced cell death
31. Fas ligand-induced apoptosis as a mechanism of immune privilege
32. Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis
33. ICE family proteases: Mediators of all apoptotic cell death?
34. Complete amino acid sequence of a β-galactoside-binding lectin from human placenta
35. The family of metazoan metal-independent β-galactoside-binding lectins: Structure, function and molecular evolution
36. Galectin-1 from ovine placenta: Complete primary structure, physico-chemical properties and implications in the T cell death
37. Purification of galectin-3 from urine placenta: Developmentally regulated expression and immunological relevance
38. Galectin-3 stimulates cell proliferation
39. Retinoic acids inhibit activation-induced apoptosis in T cell hybridomas and thymocytes
40. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation
41. Galectin: A family of animal lectins that decipher glycocodes
42. A targeted of glucocorticoid receptor antisense transgene increases thymocytes apoptosis and alters thymocytes development
43. The proto-oncogene Bcl-2 an its rol in regulating apoptosis
44. Introduction to galectin
45. Prevention and therapy with electrolectin of experimental autoimmune myasthenia gravis in rabbits
46. Rat olfactory neurons can utilize the endogenous lectin L-14, in a novel adhesion mechanism
47. Immunocytochemical study of the distribution of a 16 kDa galectin in the chicken retina
48. Glucocorticoid-induced thymocyte apoptosis: Inhibition by interleukin-2 and interleukin-4
49. Apoptosis by death factors
50. Expression and function of mouse Fas antigen on immature and mature T cells
51. The Fas counterattack: Cancer as a site of immune privilege
52. Recombinant human β-galactoside-binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis
53. GRIFIN, a novel lens-specific protein related to the galectin family
54. Apoptosis and the maintenance of homeostasis in the immune system
55. Tissue fibronectin is an endogenous ligand for galectin-1
56. Induction of T lymphocyte apoptosis: A novel functions for galectin-1
57. Apoptosis of T cells mediated by galectin-1
58. Galectin-1 and endogenous lectin produced by human thymic epithehal cells, induces apoptosis of the human thymocytes
59. Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin
60. Regulated expression of a 16-kd galectin-like protein in activated rat macrophages
61. Rat activated macrophages produce a galectin -1-like protein which induces apoptosis of T cells: Biochemical and functional characterizations
62. Specific inhibition of lymphocyte proliferation and induction of apoptosis by CLL-I, a β-galactoside-binding lectin
63. Galectins: An evolutionarily conserved family of animals proteins with multifunctional properties: A trip from the gene to the clinical therapy
64. Specific inhibition of T-cell adhesion to extracellular matrix and pro inflammatory cytokine secretion by human recombinant galectin-1
65. Protein and gene delivery of galectin-1 suppress arthritis via T cell apoptosis
66. Regulated secretion and ultrastrucrural distributions of RMGal, a pro-apoptotic galectin-1-like protein
67. Social controls on cell survival and cell death
68. Mutation in Fas associated with human lymphoproliferative syndrome and autoimmunity
69. Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathway in activated mature T cells
70. Mature T cell of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
71. Stimulation of vascular cell proliferation β-galactoside-binding lectins
72. Apoptosis: The biochemistry and molecular biology of programmed cell death
73. Apoptosis, Fas and systemic autoimmunity: The MRL lpr/lpr model
74. The Fas antigen is involved in pheripheral but not thymic delection of T lymphocytes in T cell receptor transgenic mice
75. T cell selection in the thymus
76. Immune evasion by tumors: Involvement of CD 95 (APO-1/Fas) system and its clinical implications
77. Tissue barriers, immunosuppressive microenvironments, and privileged sites: The eyes's point of view
78. Proceedings Natural Academy of Sciences USA
79. Expression of the Fas ligand in cells of the T cell lineage
80. T-cell apoptosis detected in situ during positive and negative selection in the thymus
81. Potential use of an antagonist of cAMP-dependent protein kinase to block inhibition and modulate T-cell receptor trigger activation of cytotoxic T-lymphocytes
82. Expression of the functional soluble forms of the human Fas ligand in activated lymphocytes
83. Apoptosis in the pathogenesis and treatment of disease
84. Fas antigen expression on synovial cells was downregulated by interleukin-1 beta
85. Steroid production in the thymus: Implications for thymocites selection
86. Apoptosis in the rheumatic diseases
87. Galectin-1 modulates human melanoma cell adhesion to laminin
88. Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
89. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
90. An evolutionary perspective on apoptosis
91. Inhereted human caspase-10 mutation underlies defective lymphocyte apoptosis and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome, type II
92. Identification of autocrine negative growth factor: Mouse β-galactoside-binding protein is a cytostatic factor and cell growth regulator
93. Glucocorticoid induced thymocyte apoptosis is associated with endogenous endonucluease activation
94. Expression of galectin-3 modulates T cell growth and apoptosis
95. L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion