Inhibition of human cardiac fibroblast mitogenesis by blockade of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

Clinical and Experimental Pharmacology and Physiology

Volumn 26, Issue 7, 1999, Pages 511-513

  Hafizi, Sassan ^a   Chester, Adrian H ^a   Yacoub, Magdi H ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Cardiac; DNA synthesis; Fibroblast; Human; Protein kinase; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; DNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; THYMIDINE; TRITIUM;

ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; FIBROBLAST; FIBROBLAST CULTURE; HEART MUSCLE FIBROSIS; HUMAN; HUMAN CELL; MITOGENESIS; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; CHROMONES; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; FIBROBLASTS; FIBROSIS; FLAVONOIDS; HEART; HUMANS; MORPHOLINES; MYOCARDIUM;

EID: 0032996081     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.1999.03071.x     Document Type: Article

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