Inhibition of acetylcholine muscarinic M1 receptor function by the M1-selective ligand muscarinic toxin 7 (MT-7)

British Journal of Pharmacology

Volumn 131, Issue 3, 2000, Pages 447-452

  Olianas, Maria C ^a   Maullu, Carlo ^a   Adem, Abdu ^b   Mulugeta, Ezra ^b   Karlsson, Evert ^b   Onali, Pierluigi ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chinese hamster ovary cells; Cyclic AMP accumulation; Dendroaspis angusticeps toxin; Muscarinic receptor subtypes; N1E 115 cells; Noncompetitive antagonism; Phosphoinositide hydrolysis

Indexed keywords

ACETYLCHOLINE; ADENINE DERIVATIVE; CARBACHOL; CARBON 14; CYCLIC AMP; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INOSITOL; INOSITOL PHOSPHATE; LIGAND; MT 7; MUSCARINIC M1 RECEPTOR; RECEPTOR SUBTYPE; SNAKE VENOM; SULFUR 35; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHO CELL; CHOLINERGIC SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIGAND BINDING; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL;

ACETYLCHOLINE; ANIMALS; CARBACHOL; CELL MEMBRANE; CHO CELLS; CHOLINERGIC AGENTS; CRICETINAE; CYCLIC AMP; ELAPID VENOMS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); INOSITOL PHOSPHATES; MUSCARINIC ANTAGONISTS; N-METHYLSCOPOLAMINE; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC; TRITIUM;

EID: 0033771718     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703606     Document Type: Article

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