Induction by inhibitors of nitric oxide synthase of hyperresponsiveness in the human nasal airway

British Journal of Pharmacology

Volumn 131, Issue 2, 2000, Pages 363-369

  Turner, P J ^a   Maggs, J R L ^a   Foreman, J C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Airway hyperresponsiveness; Histamine; Human; L NAME; L NMMA; Nasal airway; Nitric oxide; Platelet activating factor

Indexed keywords

ARGININE; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; HISTAMINE; ICATIBANT; N(G) METHYLARGININE; N(G) NITRO DEXTRO ARGININE METHYL ESTER; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; THROMBOCYTE ACTIVATING FACTOR;

ADULT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; HUMAN; NORMAL HUMAN; NOSE CAVITY; NOSE CONGESTION; PRIORITY JOURNAL;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRADYKININ; BRONCHIAL HYPERREACTIVITY; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG INTERACTIONS; ENZYME INHIBITORS; HUMANS; MIDDLE AGED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; PLATELET ACTIVATING FACTOR; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ;

EID: 0033770050     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703561     Document Type: Article

References (33)

1. The effect of ptatelet activating factor on the responsiveness of the human nasal mucosa
2. Acoustic rhinometry compared with posterior rhinomanometry in the measurement of histamine- and bradykinin-induced changes in nasal airway patency
3. N(G)-nitro-L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists
4. Attenuation of human nasal airway responses to bradykinin and histamine by inhibitors of nitric oxide synthase
5. Reduction by N(G)-nitro-L-arginine methyl ester (L-NAME) of antigen-induced nasal airway plasma extravasation in human subjects in vivo
6. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition
7. Expression of nitric oxide synthase in the human nasal mucosa
8. Nitric oxide metabolites in nasal lavage fluid of patients with house dust mite allergy
9. Inhibitors of nitric oxide synthase
10. Ozone-induced airway hyperresponsiveness in patients with asthma: Role of neutrophil-derived serine proteinases
11. Oxidative epithelial damage produces hyperresponsiveness of human peripheral airways
12. Implication of oxygen radicals on airway hyperresponsiveness after ovalbumin challenge in guinea pigs
13. Exhaled and nasal nitric oxide measurements: Recommendations
14. Exhaled nitric oxide: A marker of airway inflammation
15. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids
16. Neuronal nitric oxide synthase is localised in extrinsic nerves regulating perireceptor processes in the chemosensory nasal mucosae of rats and humans
17. Lipid mediators contribute to oxygen radical-induced airway responsiveness in sheep
18. Evidence that part of the NANC relaxant response of guinea-pig trachea to electrical field stimulation is mediated by nitric oxide
19. Ozone effects on the immediate-phase response to allergen in the nasal airways of allergic asthmatic subjects
20. Peroxynitrite: A two-faced metabolite of nitric oxide
21. Nasal histamine challenges in symptomatic allergic rhinitis
22. Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro
23. Endogenous nitric oxide counteracts antigen-induced bronchoconstriction
24. Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma
25. Evidence for reduction of bradykinin-induced bronchoconstriction in guinea-pigs by release of nitric oxide
26. Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes
27. Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo
28. Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: Effect of inhaled glucocorticoid
29. Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs
30. Oral administration of L-arginine potentiates allergen-induced airway inflammation and expression of interleukin-5 in mice
31. Involvement of kinins in hyperresponsiveness induced by platelet activating factor in the human nasal airway
32. 2 receptor antagonist, inhibits antigen-induced hyperresponsiveness in subjects with seasonal allergic rhinitis
33. Antigen-provoked increase in histamine reactivity: Observations on mechanisms