Hepatocyte transplantation: Advancing biology and treating children

Clinics in Liver Disease

Volumn 4, Issue 4, 2000, Pages 929-945

  Ng, Vicky Lee ^a   Alonso, Maria ^c,d   Bezerra, Jorge A ^b,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b 985160 Nebraska Medical Center   (United States)

^c Division of Pediatric Surgery

^d UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TRANSPLANTATION; CLINICAL FEATURE; DISEASE ASSOCIATION; GRAFT SURVIVAL; HUMAN; LIVER DISEASE; LIVER TRANSPLANTATION; ORGAN DONOR; REVIEW; SURGICAL TECHNIQUE; TREATMENT INDICATION;

EID: 0033764192     PISSN: 10893261     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1089-3261(05)70147-1     Document Type: Review

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5. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats
6. Replacement of liver function in rats by transplantation of microcarrier-attached hepatocytes
7. Restoration of liver function in Gunn rats without immunosuppression using transplanted microencapsulated hepatocytes
8. Treatment of hypercholesterolemia in the Watanabe rabbit using allogeneic hepatocellular transplantation under a regeneration stimulus
9. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation
10. Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
11. Correction of hyperbilirubinemia in the glucuronyltransferase-deficient rat by intraportal hepatocyte transplantation
12. Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation
13. Permanent engraftment and function of hepatocytes delivered to the liver: Implications for gent therapy and liver repopulation
14. Hepatocyte transplantation
15. Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium
16. Hepatocytes exhibit superior transgene expression after transplantation into liver and spleen compared with peritoneal cavity or dorsal fat pad: Implications for hepatic gene therapy
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18. Human fetal hepatocyte transplantation in patients with fulminant hepatic failure
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21. Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3- cydohexanedione)
22. Selective intraporal hepatocyte transplantation in analbuminemic and Gunn rats
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25. Beneficial effect of hepatocyte transplantation on hepatic failure in rats
26. Expression of human alpha 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes
27. In vivo gene therapy of hemophilia B: Sustained partial correction in factor IX-deficient dogs
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29. Observations on the fine structure of long-survived isolated hepatocytes inoculated into rat spleen
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31. Treatment of hereditary tyrosinaemia type I by inhibition of 4- hydroxyphenylpyruvate dioxygenase
32. Zonal regulation of gene expression during liver regeneration of urokinase transgenic mice
33. Long-term maintenance of the adult pattern of liver-specific expression for P-450b, P-450e, albumin and alpha-fetoprotein genes in intrasplenically transplanted hepatocytes
34. Studies into the mechanism of reversal of experimental acute hepatic failure by hepatocyte transplantation. I
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36. Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes
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38. Morphology and function of isolated hepatocytes transplanted into rat spleen
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41. Long-term correction of albumin levels in the Nagase analbuminemic rat: Repopulation of the liver by transplanted normal hepatocytes under a regeneration response
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43. Alburnin-deficient rat mutant
44. Functional assessment of proliferating hepatocytes stimulated by hepatic stimulatory substance in ascorbic acid biosynthetic enzyme-deficient rats
45. Restoration of serum albumin levels in Nagase analbuminemic rats by hepatocyte transplantation
46. Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I
47. Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation
48. Rapid clearance of transplanted hepatocytes from pulmonary capillaries in rats indicates a wide safety margin of liver repopulation and the potential of using surrogate albumin particles for safety analysis
49. Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents
50. Replacement of diseased mouse liver by hepatic cell transplantation
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52. Transfer of bilirubin uridine diphosphate-glucuronyltransferase to enzyme-deficient rats
53. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
54. Preparation of isolated rat liver cells
55. Histidinemia in mice: A metabolic defect treated using a novel approach to hepatocellular transplantation
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66. Hepatocyte transplantation for the low-density lipoprotein receptor-deficient state: A study in the Watanabe rabbit
67. Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes
68. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene
69. Expansion of transplanted hepatocytes during liver regeneration
70. Intrahepatic transplantation of normal hepatocytes prevents Wilson's disease in Long-Evans cinnamon rats