Aprotinin improves pulmonary function during reperfusion in an isolated lung model

Annals of Thoracic Surgery

Volumn 70, Issue 5, 2000, Pages 1671-1674

  Mathias, Menen A ^a   Tribble, Curtis G ^a   Dietz, Jeffrey F ^a   Nguyen, Richard P ^a   Shockey, Kimberly S ^a   Kern, John A ^a   Kron, Irving L ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ;

ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; CONFERENCE PAPER; CONTROLLED STUDY; LUNG FUNCTION; LUNG TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY;

ANIMALS; APROTININ; HYPERTONIC SOLUTIONS; LUNG; RABBITS; REPERFUSION; REPERFUSION INJURY; SERINE PROTEINASE INHIBITORS;

EID: 0033763105     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(00)01767-7     Document Type: Conference Paper

References (16)

1. Pathophysiology of ischaemia reperfusion injury: Central role of the neutrophil
2. Use of aprotinin in pediatric lung transplantation
3. Addition of aprotinin to organ preservation solutions decreases lung reperfusion injury
4. Aprotinin is associated with a decrease in nitric oxide production during cardiopulmonary bypass
5. Reduced neutrophil infiltration protects against lung reperfusion injury after transplantation
6. Selective adenosine-A2A activation reduces lung reperfusion injury, following transplantation
7. Low-dose sodium nitroprusside reduces pulmonary reperfusion injury
8. Intratracheal surfactant administration preserves airway compliance during lung reperfusion
9. Both blood and crystalloid-based extracellular solutions are superior to intracellular solutions for lung preservation
10. A human urinary protease inhibitor (Ulinistatin) inhibits neutrophil extracellular release of elastase during cardiopulmonary bypass
11. Neutrophil elastase inhibitor, ONO-5046, modulates acid-induced lung and systemic injury in rabbits
12. ONO-5046, an elastase inhibitor, attenuates endotoxin-induced acute lung injury in rabbits
13. Effects of a neutrophil elastase inhibitor (ONO-5046) on acute pulmonary injury induced by tumor necrosis factor alpha(TNFα) and activated neutrophils in isolated perfused rabbit lungs
14. Recombinant Kunitz protease inhibitor ameliorates reperfusion injury in rat lung transplantation
15. Aprotinin enhances the endogenous release of interleukin-10 after cardiac operations