Aprotinin enhances the endogenous release of interleukin-10 after cardiac operations

Annals of Thoracic Surgery

Volumn 65, Issue 1, 1998, Pages 66-69

  Hill, Gary E ^a   Diego, Robert P ^a   Stammers, Alfred H ^a   Huffman, Suzanne M ^a   Pohorecki, Roman ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; CYTOKINE; DEXAMETHASONE; GLUCOCORTICOID; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; METHYLPREDNISOLONE; METHYLXANTHINE; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANESTHESIA INDUCTION; ANTIINFLAMMATORY ACTIVITY; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART SURGERY; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

APROTININ; CARDIOPULMONARY BYPASS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-10; MIDDLE AGED; SERINE PROTEINASE INHIBITORS;

EID: 0031881751     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(97)01037-0     Document Type: Conference Paper

References (25)

1. 1. Hill GE, Whitten CW, Landers DF. The influence of cardiopulmonary-bypass on cytokines and cell-cell communication. J Cardiothorac Vasc Anesth 1997;11:367-75.
2. 2. Malefyt RW, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-20.
3. 3. Willems F, Marchant A, Delville JP, et al. Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes. Eur J Immunol 1994;24:1007-9.
4. 4. Eppinger MJ, Ward PA, Bolling SF, Deeb GM. Regulatory effects of interleukin-10 on lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg 1996;112:1301-6.
5. 5. Tabardel Y, Duchateau J, Schmartz D, et al. Corticosteroids increase blood interleukin-10 levels during cardiopulmonary bypass in men. Surgery 1996;119:76-80.
6. 6. Hill GE, Alonso A, Spurzem JR, Stammers AH, Robbins RA. Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans. J Thorac Cardiovasc Surg 1995;110:1658-62.
7. 7. Harward TRS, Martin TD, Welborn MB, et al. Tumor necrosis factor-α (TNF-α), interleukin-1β), and interleukin-8 (IL-8) are released following thoracoabdominal aneurysm repair and TNF-α levels are related to patient outcome. Surg Forum 1995;46:360-2.
8. 8. Hack CE, De Groot ER, Felt-Bersma JF, et al. Increased plasma levels of interleukin-6 in sepsis. Blood 1989;74: 1704-10.
9. 9. Hennein HA, Ebba H, Rodriquez JL, et al. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg 1994;108:626-35.
10. 10. Menasché P, Haydar S, Peynet J, et al. A potential mechanism of vasodilation after warm heart surgery. J Thorac Cardiovasc Surg 1994;107:293-9.
11. 11. Seghaye MC, Grabitz RG, Duchateau J, et al. Inflammatory reaction and capillary leak syndrome related to cardiopulmonary bypass in neonates undergoing cardiac operations. J Thorac Cardiovasc Surg 1996;112:687-97.
12. 12. Journois D, Pouard P, Greeley WJ, Mauriat P, Vouhe P, Safran D. Hemofiltration during cardiopulmonary bypass in pediatric cardiac surgery. Anesthesiology 1994;81:1181-9.
13. 13. Journois D, Israel-Biet D, Pouard P, et al. High volume, zero-balanced hemofiltration to reduce delayed inflammatory response to cardiopulmonary bypass in children. Anesthesiology 1996;85:965-76.
14. 14. Sawa Y, Shimazaki Y, Kadoba K, et al. Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations. J Thorac Cardiovasc Surg 1996;111:29-35.
15. 15. Teoh KHT, Bradley CA, Gauldie J, Burrows H. Steroid inhibition of cytokine-mediated vasodilation after warm heart surgery. Circulation 1995;92(Suppl II):II347-53.
16. 16. Burger D, Dayer JM. Inhibitory cytokines and cytokine inhibitors. Neurology 1995;45(Suppl 6):S39-43.
17. 17. Lecuwenberg JFM, Jeunhomme TMAA, Buurman WA. Slow release of soluble TNF receptors by monocytes in vitro. J Immunol 1994;152:4036-43.
18. 18. Whitten CW, Latson TW, Allison PM, et al. Does aprotinin inhibit cardiopulmonary bypass-induced inflammation? Anesthesiology 1992;77:A266.
19. 19. Wendel HP, Heller W, Michel J, et al. Lower cardiac tropinin T levels in patients undergoing cardiopulmonary bypass and receiving high-dose aprotinin therapy indicate reduction of perioperative myocardial damage. J Thorac Cardiovasc Surg 1995;109:1164-72.
20. 20. Stack G, Baril L, Napychank P, Snyder EL. Cytokine generation in stored, white cell-reduced, and bacterially contaminated units of red cells. Transfusion 1995;35:199-203.
21. 21. McBride WT, Armstrong MA, Crockard AD, McMurray TJ, Rea JM. Cytokine balance and immunosuppressive changes at cardiac surgery: contrasting response between patients and isolated CPB circuits. Br J Anaesth 1995;75:724-33.
22. 22. Wan S, Marchant A, DeSmet JM, et al. Human cytokine responses to cardiac transplantation and coronary artery bypass grafting. J Thorac Cardiovasc Surg 1996;111:469-77.
23. 23. Seghaye MC, Duchateau J, Bruniaux J, et al. Interleukin-10 release related to cardiopulmonary bypass in infants undergoing cardiac operations. J Thorac Cardiovasc Surg 1996;111: 545-53.
24. 24. Jilg S, Barsig J, Leist M, Kusters S, Volk HD, Wendel A. Enhanced release of interleukin-10 and soluble tumor necrosis factor receptors as novel principles of methylxanthine action in murine models of endotoxic shock. J Pharmacol Exp Ther 1996;278:421-31.
25. 25. Van der Poll T, Coyle SM, Barbosa K, Braxton CC, Lowry SF. Epinephrine inhibits tumor necrosis factor-α and potentiates interleukin 10 production during human endotoxemia. J Clin Invest 1996;97:713-9.