Reversal of multidrug resistance by 7-O-Benzoylpyripyropene A in multidrug-resistant tumor cells

Journal of Antibiotics

Volumn 53, Issue 10, 2000, Pages 1201-1206

  Rho, M C ^a   Hayashi, M ^a   Fukami, A ^a   Obata, R ^a   Sunazuka, T ^a   Tomoda, H ^a   Komiyama, K ^a   Omura, S ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 O BENZOYLPYRIPYROPENE A; ACYL COENZYME A; ANTINEOPLASTIC AGENT; AZIDOPINE; CHOLESTEROL ACYLTRANSFERASE; DOXORUBICIN; ENZYME INHIBITOR; GLYCOPROTEIN P; TRITIUM; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL STRAIN KB; CONTROLLED STUDY; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG RESISTANCE; DRUG SENSITIVITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LEUKEMIA P 388; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; TUMOR CELL;

EID: 0033762601     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.1201     Document Type: Article

References (29)

1. Merck Frosst Award Lecture 1998. Molecular dissection of the human multidrug resistance P-glycoprotein
2. Biochemical, cellular, and pharmacological aspects of the multidrug transporter
3. Competitive inhibition by verapamil of ATP-dependent high affinity vincristine binding to the plasma membrane of multidrug-resistant K562 cells without calcium ion involvement
4. The biochemistry of P-glycoprotein-mediated multidrug resistance
5. Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein
6. Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene
7. Pharmacology of drugs that alter multidrug resistance in cancer
8. Pharmacologic circumvention of multidrug resistance
9. Enhancement of drug accumulation by andrastin A produced by Penicillium sp. FO-3929 in vincristine-resistant KB cells
10. Reversal of multidrug resistance (MDR) by aspidofractinine-type indole alkaloids
11. Reversal of multidrug resistance by kopsiflorine isolated from Kopsia dasyrachis
12. Pyripyropenes, highly potent inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus
13. Pyripyropenes, novel potent inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus I. Production, isolation, and biological properties
14. Relative and absolute stereochemistry of pyripyropene A, a potent bioavailable inhibitor of acyl-CoA: Cholesterol acyltransferase (ACAT)
15. Chemical modification and structure-activity relationships of pyripyropenes. 1. Modification at the four hydroxyl groups
16. Chemical modification and structure-activity relationships of pyripyropenes; Potent, bioavaillable inhibitor of Acyl-CoA: Cholesterol O-acyltransferase (ACAT)
17. Vincristine-resistant human cancer KB cell line and increased expression of multidrug-resistance gene
18. Decreased retention of actinomycin D as the basis for cross-resistance in anthracycline-resistant sublines of P388 leukemia
19. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
20. Evidence of altered influx of adriamycin into anthracycline-resistant cells
21. Azidopine photoaffinity labeling of multidrug resistance-associated glycoproteins
22. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
23. Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma
24. Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia
25. Dexverapamil to modulate vinblastine resistance in metastatic renal cell carcinoma
26. Treatment of multidrug resistant (MDR1) murine leukemia with P-glycoprotein substrates accelerates the course of the disease
27. Reversal of anticancer multidrug resistance by the ardeemins
28. Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyl-dibenzosuberane modulator, LY335979
29. Structure-activity relationships study of pyripyropenes: Reversal of cancer cell multidrug resistance