Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation

Genesis

Volumn 28, Issue 1, 2000, Pages 1-14

  Pfendler, Kristina C ^a   Yoon, JoonWon ^a   Taborn, Gregory U ^a   Kuehn, Michael R ^b   Iannaccone, Philip M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bmp 5; Double mutants; Gastrulation; Implantation; Mesoderm; Mouse; Nodal

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GASTRULATION; GENE EXPRESSION; GENE MUTATION; GENOTYPE; MESODERM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BONE MORPHOGENETIC PROTEINS; EMBRYO IMPLANTATION; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GASTRULA; GENOTYPE; MALE; MESODERM; MICE; MICE, INBRED C3H; MICE, MUTANT STRAINS; MUTATION; PHENOTYPE; TRANSFORMING GROWTH FACTOR BETA;

MURINAE; VERTEBRATA;

EID: 0033761505     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1526-968X(200009)28:1<1::AID-GENE10>3.0.CO;2-X     Document Type: Article

References (71)

1. Implantation and decidualization in rodents
2. Cellular interpretation of multiple TGF-β signals: Intracellular antagonism between activin/bVg1 and BMP-2/4 signaling mediated by smads
3. Novel retrovirally induced embryonic lethal mutation in the mouse: Assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral integration
4. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
5. Leukemia inhibitory factor (LIF) and LIF receptor expression in human endometrium suggests a potential autocrine/paracrine function in regulating embryo implantation
6. Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF-receptor in implantation
7. Expression of betacellulin and epiregulin genes in the mouse uterus temporally by the blastocyst solely at the site of its apposition is coincident with the 'window' of implantation
8. Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos
9. Embryological effect of a short-ear lethal allele in the mouse
10. Embryological effects of a minute deficiency in linkage group II of the mouse
11. Haploinsufficient phenotypes in BMP4 heterozygous null mice and modification by mutations in Gli3 and Alx4
12. Immunohistochemical localization of two monoclonal antibody-defined carbohydrate antigens during early murine embryogenesis
13. Stage-specific expression of three cell surface carbohydrate antigens during murine spermatogenesis detected with monoclonal antibodies
14. The blood group I antigen defined by monoclonal antibody C6 is a marker of early mesoderm during murine embryogenesis
15. Immunohistochemical localization of the early embryonic antigen (SSEA-1) in postimplantation mouse embryos and fetal and adult tissues
16. Functions of fibroblast growth factors in vertebrate development
17. The development of three manifestations of the short ear gene in the mouse
18. Further morphological effects of the short ear gene in the house mouse
19. Modifiers of the pleiotropic effects of the short ear gene in the mouse
20. Effects of the short ear gene in the mouse on cartilage formation in healing bone fractures
21. Apoptosis in decidual tissue regression and reorganization
22. The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
23. The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo
24. mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation
25. TGF-β signalling from cell membrane to nucleus through SMAD proteins
26. Growth factors in development: The role of TGF-B related polypeptide signalling molecules in embryogenesis
27. Wnt world: A window on gastrulation, development, and cancer
28. Insertional mutation of a gene involved in growth regulation of the early mouse embryo
29. Has the quest for a Wnt receptor finally frizzled out?
30. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
31. Xnr4: Xenopus Nodal-related gene expressed in the Spemann organizer
32. Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion
33. Embryonic signals and the initiation of blastocyst implantation
34. BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice
35. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF-B superfamily
36. What do BMPs do in mammals? Clues from the mouse short-ear mutation
37. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus
38. Whole mount in situ hybridization to study gene expression during mouse development
39. Short ears an autosomal mutation in the house mouse
40. The TGF-β-related DVR gene family in mammalian development
41. Cloning and expression of three members of the zebrafish Bmp family: Bmp2a, Bmp2b and Bmp4
42. TGF-beta signal transduction
43. The Wnt family of developmental regulators
44. Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis
45. Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse
46. Smad2 role in mesoderm formation, left-right patterning and craniofacial development
47. Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats
48. Cytokines ha implantation
49. Molecular genetic analysis of the dilute-short ear (d-se) region of the mouse
50. FGF signaling in mouse gastrulation and anteroposterior patterning
51. Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations
52. Spontaneous mutations recovered as mosaics in the mouse specific-locus test
53. X-ray-induced mutations in mice
54. Cytokines and embryo implantation
55. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo
56. Transforming growth factor-β in the early mouse embryo: Implications for the regulation of muscle formation and implantation
57. Interaction of Wnt and Activin in dorsal mesoderm induction in Xenopus
58. Mice lacking Bmp6 function
59. Early embryonic lethality in Bmp5; Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup
60. The type II Activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice
61. Regulation of epidermal induction by BMP2 and BMP7 signaling
62. Nodal indues ectopic goosecoid and lim1 expression and axis duplication in zebrafish
63. The enamel knot as a signaling center in the developing mouse tooth
64. Nodal expression in the primitive Endoderm is required for specification of the anterior axis during mouse gastrulation
65. Embryonic signaling at implantation in the mouse
66. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
67. Mechanisms of Wnt signaling in development
68. Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
69. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
70. Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
71. Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation