Multiple functions of Dlx genes

International Journal of Developmental Biology

Volumn 44, Issue 6, 2000, Pages 619-626

  Merlo, G R ^a   Zerega, B ^a   Paleari, L ^a   Trombino, S ^a   Mantero, S ^a   Levi, G ^a  

^a CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Brain development; Craniofacial; Dlx; Limb; Osteogenesis

Indexed keywords

GENE PRODUCT; PROTEIN DISTAL LESS; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BRAIN DEVELOPMENT; CRANIOFACIAL DEVELOPMENT; DROSOPHILA; EMBRYO; FOOT MALFORMATION; GENE EXPRESSION; GENE FUNCTION; GENETIC LINKAGE; HAND MALFORMATION; HOMEOBOX; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; DNA-BINDING PROTEINS; DROSOPHILA; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OSTEOGENESIS; SENSE ORGANS; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 0033760811     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Craniofacial, vestibular and the bone defects in mice lacking distal-less-related gene Dlx5
2. Combinatorial expression of three zebrafish genes related to distal-less: Part of a homeobox gene code for the head
3. Inteneuron migration from basal forebrain to neocortex: Dependence on Dlx genes
4. Mutation of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late-born striatal cells
5. Differential origin of neocortical projection and local circuit neurons/ role of Dlx genes in neocortical interneuronogenesis
6. The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos
7. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt3 in the embryonic day 12.5 mouse forebrain defined potentially transverse and longitudinal segmental boundaries
8. An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons
9. Developmental regulatory mechanisms in the evolution of insect diversity
10. Dlx5 and Dlx6: An evolutionary conserved pair of murine homeobox genes expressed in the embryonic skeleton
11. Distal-less encodes a homeodomain protein required for limb bud development in Drosophila
12. Specification of limb development in the Drosophila embryo by the positional cues from segmentation genes
13. The triple origin of skull in higher vertebrates: A study in quail-chick chimeras
14. Dlx5 regulates regional development of the branchial arches and sensory capsules
15. Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs
16. Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development
17. Relationship between the genomic organization and the overlapping embryonic expression patterns of the zebrafish Dlx genes
18. Specific craniofacial cartilage dysmorphogenesis coincides with a loss of Dlx gene expression in retinoic acid-treated zebrafish embryos
19. Transcriptional activation by the homeodomain protein distal-less 3
20. The expression pattern of the Distal-less homeobox-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal activity, pattern formation, and cartilage differentiation
21. Dlx-5 in limb initiation in the chick embryo
22. Drosophila terminalia as an appendage-like structure
23. Nkx5-1 controls semicircular canal formation in the mouse inner ear
24. Evolution and development of the vertebrate skull: The role of pattern formation
25. Insertional mutation of the mouse Msx1 homeobox gene by a lac-Z reporter gene
26. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny
27. Proximal-distal axis formation in the Drosophila leg
28. Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation
29. Sequence, organization and transcription of the Dlx-1 and Dlx-2locus
30. Placental failure in mice lacking the homeobox gene Dlx3
31. Localization of human Dlx8 to chromosome 17q21.3-q22 by fluorescent in situ hybridization
32. Genomic analysis of a new mammalian distal-less gene: Dlx-7
33. Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5
34. The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissue
35. Distal-less is a downstream gene of Deformed required forventral maxillary identity
36. Cbfa 1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
37. The origin and evolution of animal appendages
38. DLX-2, MASH-1, and MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain
39. Identification of a mutation in DLX3 associated with tricho-dento-osseous (TDO) syndrome
40. A common DLX3 gene mutation is responsible for tricho-dento-osseous syndrome in Virginia and North Carolina families
41. Members of the Dlx- and Nkx2-gene families are regionally expressed in the developing forebrain
42. Role of Dlx1 and Dlx2 in proximodistal patterning of the branchial arches. Mutations of Dlx-1, Dlx-2, and Dlx-1 and Dlx-2 alter morphogenesis of proximal skeletal elements derived from the first and second arches
43. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation of the forebrain
44. Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4
45. Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development
46. Stage-specific expression of Dlx-5 during osteoblast differentiation: Involvement in regulation of osteocalcin gene expression
47. Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development
48. Assignment of the human homolog of mouse Dlx3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization
49. Physical mapping of the split hand/split foot locus on chromosome 7 and implication in syndromic ectrodactyly
50. Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-mycgenes and apoptosis
51. Cloning and characterization of two members of the vertebrate Dlx gene family
52. The evolution of the vertebrate Dlx gene family
53. Brista: A gene involved in the specification and differentiation of distal cephalic and thoracic structures in Drosophila melanogaster
54. Regionalization of the developing forebrain: A comparison of FORSE-1, Dlx-2, and BF-1
55. The development of the vertebrate inner ear
56. Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less
57. Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene
58. Ectodermal placodes: Contributions to the development of the vertebrate head
59. An early phase of embryonic Dlx5 expression defines the rostral boundary of the neural plate
60. A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forehead
61. Hetero-dimerization of Msx and Dlx homeoproteins results in functional antagonism
62. rDLX, a novel distal-less-like homeoprotein, is expressed in developing cartilages and discrete neuronal tissues