Correlation of tight junction morphology with the expression of tight junction proteins in blood-brain barrier endothelial cells

European Journal of Cell Biology

Volumn 79, Issue 10, 2000, Pages 707-717

  Liebner, Stefan ^a   Kniesel, Uwe ^a,b   Kalbacher, Hubert ^c   Wolburg, Hartwig ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF HOHENHEIM   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Blood brain barrier; Chicken; Claudin 1; Claudin 5; Occludin; Rat; Tight junction

Indexed keywords

CELL PROTEIN; CLAUDIN 1; CLAUDIN 5; MEMBRANE PROTEIN; OCCLUDIN; UNCLASSIFIED DRUG; ZONULA OCCLUDENS PROTEIN 1;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CELL CULTURE; CELL MEMBRANE; CELL STRUCTURE; CELL TYPE; CHICKEN; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; IMMUNOFLUORESCENCE TEST; MAMMAL CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPECIES DIFFERENCE; TIGHT JUNCTION;

EID: 0033759717     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00101     Document Type: Article

References (44)

1. Permeability and transport of glial blood-brain barriers
2. Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors
3. ZO-1 isoform distribution reveals two classes of tight junctions
4. Two classes of tight junctions are revealed by ZO-1 isoforms
5. A dominant mutant of occludin disrupts tight junction structure and function
6. Cytoplasmic regulation of tight junction permeability: Effect of plant cytokinins
7. Primary culture of capillary endothelium from rat brain
8. Brain microvessel endothelial cells in tissue culture: A model for study of blood-brain barrier permeability
9. Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells
10. Development of the blood-brain barrier
11. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
12. Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
13. Occludin: A novel integral membrane protein localizing at tight junctions
14. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
15. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
16. Manner of interaction of heterogeneous claudin species within and between tight junction strands
17. The pecten oculi of the chicken as a new in vivo model of the blood-brain barrier
18. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
19. Occludin as a possible determinant of tight junction permeability in endothelial cells
20. Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2 and ZO-3, with the COOH termini of claudins
21. Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin
22. A tentacle-type peptide resin allows the simultaneous sythesis of peptide antigens and of an affinity matrix for antipeptide antibodies
23. Quantification of tight junction complexity by means of fractal analysis
24. Development of blood-brain barrier tight junctions in the rat cortex
25. The tight junctions of the blood-brain barrier
26. Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme
27. Maturation of the blood-retina barrier in the pecten oculi of the developing chicken
28. Untersuchung des Zusammenhangs zwischen elektrophysiologischem Verhalten und morphologischem Erscheinungsbild von tight junctions in MDCK-Epithelzellen
29. Capillary ultrastructure and the blood-brain barrier in human malignant brain tumors
30. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
31. Endothelial claudin. Claudin-5/tmvcf constitutes tight junction strands in endothelial cells
32. Freeze-fracture analysis of endothelial cell membranes in rabbit carotid arteries subjected to short-term atherogenic stimuli
33. Occludin 1B, a variant of the tight junction protein occludin
34. The tight junctions of the leptomeningeal blood-cerebrospinal fluid barrier during development
35. Immune function of the blood-brain barrier: Incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro
36. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
37. Possible involvement of phosphorylation of occludin in tight junction formation
38. The blood-brain barrier of a reptile, Anolis carolinensis. A freeze-fracture study
39. 2+ resorption
40. The epithelial tight junction: Structure, function and preliminary biochemical characterization
41. Developing nervous tissue induces formation of blood brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras
42. Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system
43. Occludin and claudins in tight-junction strands: Leading or supporting players?
44. Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes