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1
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-
0007356376
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Preliminary data from the San Francisco ICAAC meeting
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187765
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(1995)
ICAAC
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-
-
-
3
-
-
3142625155
-
In vivo efficacy evaluations of U-100592 and U-100766, new oxazolidinone antibiotics
-
188663; Abs F221; note
-
(1995)
ICAAC
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-
Ford, C.W.1
Hamel, J.C.2
Moerman, J.K.3
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Yancey, R.J.6
Barbachyn, M.R.7
Hutchinson, D.K.8
Brickner, S.J.9
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7
-
-
0030027833
-
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant Gram-positive bacterial infections
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198175; note
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J Med Chem
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Brickner, S.J.1
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Garmon, S.A.6
Grega, K.C.7
Hendges, S.K.8
Toops, D.S.9
Ford, C.W.10
Zurenko, G.E.11
-
8
-
-
0030034825
-
Activities of RPR-106972 (a new oral streptogramin), cefditoren (a new cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parental agents against 203 penicillin-susceptible and-resistant Pneumococci
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200790; note
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(1996)
Antimicrob Agents Chemother
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-
Spangler, S.K.1
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9
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0029942573
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In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents
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210234; note
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(1996)
Antimicrob Agents Chemother
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Zurenko, G.E.1
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Kilburn, J.O.5
Glickman, S.E.6
Hutchinson, D.K.7
Barbachyn, M.R.8
Brickner, S.J.9
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13
-
-
0029940428
-
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections
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214406; note
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(1996)
Antimicrob Agents Chemother
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Ford, C.W.1
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Stapert, D.5
Yancey, R.J.6
Hutchinson, D.K.7
Barbachyn, M.R.8
Brickner, S.J.9
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16
-
-
0007399862
-
Second International Symposium: Recent advances in the Chemistry of Anti-Infective Agents, Churchill College, Cambridge, UK
-
216320
-
IDDB Meeting Report 1996 July 7-10
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-
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19
-
-
0007399863
-
Synthesis and SAR of novel antibacterial oxazolidinones
-
224408; SL 09.2
-
Int Symp Med Chem 1996
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-
Barbachyn, M.B.1
Hutchinson, D.K.2
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Lindberg, T.J.8
Manninen, P.R.9
Munesada, K.10
Reid, R.J.11
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20
-
-
0029819239
-
In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfoprostin-quinupristein against Staphlococcus aureus and Staphylococcus epidermidis
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235036; note
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Mulazimoglu, L.1
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23
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-
3142583970
-
Susceptibility of 115 penicillin susceptible and -resistant pneumococci to two oxazolidinones compared to penicillin G, ceftriaxone, teicoplanin, vancomycin, rifampicin and imipenem
-
235097; Abs F218
-
(1995)
ICAAC
, vol.35
-
-
Spangler, S.K.1
Jacobs, M.R.2
Appelbaum, P.C.3
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25
-
-
0007356237
-
In vitro activity of oxazolidinone compounds U100592 (592) and U100766 (766) versus Staphylococcus aureus (SA) and Staphylococcus epidermidis (SE)
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235106; Abs F215
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(1995)
ICAAC
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-
Kaatz, G.W.1
Seo, S.M.2
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26
-
-
3142583969
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Comparative in vitro activities of vancomycin and the oxazolidinones U-100592 and U-100766 against 300 clinical staphylococcal isolates
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235108; Abs F213
-
(1995)
ICAAC
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-
-
Jenkins, S.G.1
Lewis, J.W.2
-
27
-
-
3142513109
-
Activity of oxazolidinones U-100592 and U-100766 in vitro against penicillin-resistant and cephalosporin-resistant strains of S pneumoniae
-
235114; Abs F212
-
(1995)
ICAAC
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-
Mason, E.O.1
Lamberth, L.B.2
Kaplan, S.L.3
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28
-
-
0002689090
-
Synthesis of U-100592 and U-100766, two new oxazolidinone antibacterial agents in clinical trials for treatment of multiply resistant Gram-positive infections
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235119; Abs F208
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(1995)
ICAAC
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-
Brickner, S.J.1
Hutchinson, D.K.2
Barbachyn, M.R.3
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Manninen, P.R.7
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Ulanowicz, D.A.9
Kilburn, J.O.10
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30
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0030793842
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Mechanism of action of oxazolidinones: Effects of linezolid and eperezolid on translation reactions
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279625; note
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Swaney, S.M.6
Dunyak, D.S.7
Demyan, W.F.8
Buysse, J.M.9
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33
-
-
0007404338
-
Linezolid binds to the 50S ribosomal subunit and competes with the binding of eperezolid, chloramphenicol and lincomycin
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286620; Abs C101
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(1997)
ICAAC
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Lin, A.H.1
Murray, R.W.2
Marotti, K.R.3
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35
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0003201380
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Absorption, distribution, metabolism, and excretion of the oxazolidinone antibiotic Linezolid (PNU-100766) in the Sprague Dawley rat
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297126; Abs A123
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Chiba, K.1
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Howard, M.R.7
Martin, I.J.8
Ozawa, N.9
Passingham, B.J.10
Parks, H.G.11
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36
-
-
0001811967
-
Comparative in vitro activity of daptomycin versus vancomycin, linezolid, and syndercid against methicillin-resistant and susceptible staphylococci, vancomycin-intermediate susceptible Staphylococcus aureus (VISA) and vancomycin-susce
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297478; Abs C146
-
(1998)
ICAAC
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-
Rybak, M.J.1
Hershberger, E.2
Moldovan, T.3
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39
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0007441843
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Deutsche Bank Research: US Investment Research: Pharmacia and Upjohn Deutsche Bank Research
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316769; December 4
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(1998)
Analyst Report
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40
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0007404339
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(1999)
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50
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-
0007401609
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Preliminary phase III data suggest new antibiotic ZYVOX (linezolid) is effective for the treatment of challenging Gram-positive bacterial infections
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341351; September 27
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(1999)
Pharmacia and Upjohn Inc Press Release
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-
-
52
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-
0001822276
-
Safety and tolerance of linezolid in phase II trials
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342342; Abs 1763
-
(1999)
ICAAC
, vol.39
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-
Wilks, N.E.1
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54
-
-
0007403636
-
Phase III trials evaluate the safety of new antibiotic Zyvox (linezolid) in the treatment of Gram-positive bacterial infections
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348193; Pharmacia and Upjohn Co; November 22
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(1999)
Press Release
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-
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55
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0007357426
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Pharmacia and Upjohn study suggests investigational new antibiotic Zyvox (linezolid) may result in faster hospital discharge when treating MRSA infections
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349555; Pharmacia and Upjohn Co; December 6
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(1999)
Press Release
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-
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56
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0007357126
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Pharmacia and Upjohn submits European filing for new antibiotic Zyvoxa
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349970; Pharmacia and Upjohn Inc; December 9
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(1999)
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57
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0003711294
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Merrill Lynch: Global healthcare bulletin
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358429; February 15
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58
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0007441844
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FDA advisory committee recommends approval of Zyvox (linezolid) first antibiotic in a completely new class in 35 years
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360804; Pharmacia and Upjohn Co; March 24
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(2000)
Press Release
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-
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60
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0007401611
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FDA approves Zyvox - The first antibiotic in a completely new class in 35 years: New treatment option for a significant public health challenge
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363503; Pharmacia Corp; April 18
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(2000)
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61
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62
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0034018950
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In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against staphylococci and enterococci, including vancomycin-intermediate and -resistant strains
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365694
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Merrill Lynch - Global Healthcare Bulletin
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366910; May 1
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70
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0007440673
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76
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0031893770
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Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative Staphylococci, Enterococcus faecalis, and Enterococcus faecium
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78
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0033028631
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In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to the novel oxazolidinones eperezolid (PNU-100592) and linezolid (PNU-100766)
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381149; note
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Hoppe, J.E.1
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81
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34447110079
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Synthesis and structure-activity relationships of new tropone-substituted oxazolidinone antibacterial agents
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381152; Abs F206
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(1995)
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Barbachyn, M.R.1
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