In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae

International Journal of Antimicrobial Agents

Volumn 12, Issue 2, 1999, Pages 141-144

  Kearney, J A ^a   Barbadora, K ^a   Mason, E O ^b   Wald, E R ^a   Green, M ^a  

^a Div Allerg Immunol Infect Dis   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINDAMYCIN; EPEREZOLID; ERYTHROMYCIN; LINEZOLID;

ARTICLE; BACTERICIDAL ACTIVITY; HUMAN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; OTITIS MEDIA; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

ACETAMIDES; ACUTE DISEASE; ANTI-BACTERIAL AGENTS; CHILD; CLINDAMYCIN; DRUG RESISTANCE, MICROBIAL; ERYTHROMYCIN; HUMANS; MICROBIAL SENSITIVITY TESTS; OTITIS MEDIA; OXAZOLES; OXAZOLIDINONES; PENICILLINS; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 0033031640     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(99)00059-X     Document Type: Article

References (16)

1. Canafax D.M., Geibink G.S. Antimicrobial treatment of acute otitis media [Review]. Ann Otol Rhinol Lanryngol Suppl. 163:1994;11-14.
2. Ednie LM, Visalli MA, Jacobs MR, Appelbaum PC. Comparative activities of clarithromycin, erythromycin and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. 1996;40:1950-52.
3. Eliopoulos G.M., Wennersten C.B., Gold H.S., Mollering R.C. Jr. In vitro activities of new oxazolidinone against enterococci. Antimicrob Agents Chemother. 40:1996;1745-1747.
4. Green M., Wald E.R. Emerging resistance to antibiotics: impact on respiratory infections in the outpatient setting. Ann Allergy Asth Immun. 77:1996;167-176.
5. Jernigan D.B., Cetron M.S., Breiman R.F. Minimizing the impact of drug-resistant Streptococcus pneumoniae (DRSP). A strategy from the DRSP Working Group. J Am Med Assoc. 275:1996;206-209.
6. Jones R.N., Johnson D.M., Erwin M.E. In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinones. Antimicrob Agents Chemother. 40:1996;720-726.
7. Mason E.O., Lamberth L., Lichenstein R., Kaplan S.L. Distribution of Streptococcus pneumoniae resistant to penicillin in the USA and in-vitro susceptibility to selected oral antibiotics. J Antimicrob Chemother. 36:1995;1043-1048.
8. Mason E.O., Lamberth L.B., Kaplan S.L. In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae. Antimicrob Agents Chemother. 40:1996;1039-1040.
9. McCracken G.H. Emergence of resistant Streptococcus pneumoniae: a problem in pediatrics. Pediatr Infect Dis J. 14:1995;424-428.
10. Paradise J.L. Managing otitis media: a time for change (Commentary). Pediatrics. 96:1995;712-715.
11. Paradise J.L. Treatment guidelines for otitis media: the need for breadth and flexibility. Pediatr Infect Dis J. 14:1995;429-435.
12. Spangler S.K., Jacobs M.R., Appelbaum P.C. Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U100766), and other oral and parenteral agents against 203 penicillin-susceptible and resistant pneumococci. Antmicrob Agents Chemother. 40:1996;481-484.
13. Thomasz A. Multiple-antibiotic-resistant pathogenic bacteria. New Engl J Med. 330:1994;1247-1251.
14. Zurenko G.E., Yagi B.H., Schaadt R.D., Allison J.W., Kilburn J.O., Glickman S.E., Hutchinson D.K., Barbachyn M.R., Brickner S.J. In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents. Antimicrob Agents Chemother. 40:1996;839-845.
15. Sahm D.F., Washington J.A. Antibacterial susceptibility tests: dilutional methods. Balows A., Hausler W.J., Hermann K.L., Isenberg H.D., Shadomy H.J. Manual of Clinical Microbiology, 5th ed. 1991;1105-1116 American Society for Microbiology, Washington, DC.
16. Stratton C.W., Cooksey R.C. Susceptibility tests: special tests. Balows A., Hausler W.J., Hermann K.L., Isenberg H.D., Shadomy H.J. Manual of Clinical Microbiology, 5th ed. 1991;1153-1165 American Society for Microbiology, Washington, DC.