In vitro activity of linezolid against vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae

Diagnostic Microbiology and Infectious Disease

Volumn 34, Issue 2, 1999, Pages 119-122

  Patel, Robin ^a   Rouse, Mark S ^a   Piper, Kerryl E ^a   Steckelberg, James M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ERYTHROMYCIN; LINEZOLID; PENICILLIN G; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIAL GENE; ENTEROCOCCUS; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; OSTEOMYELITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

ACETAMIDES; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; ENTEROCOCCUS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; OXAZOLES; OXAZOLIDINONES; PENICILLIN RESISTANCE; PNEUMOCOCCAL INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; VANCOMYCIN;

EID: 0033010968     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0732-8893(99)00016-4     Document Type: Article

References (17)

1. Nosocomial enterococci resistant to vancomycin-United States, 1989-1993. MMWR. 42:1993;597-599.
2. Update Staphylococcus aureus with reduced susceptibility to vancomycin-United States, 1997 . MMWR Morbidity & Mortality Weekly Report. 46:1997;813-815.
3. Eliopoulos G.M., Wennersten C.B., Gold H.S., Moellering R.C. In vitro activities of new oxazolidinone antimicrobial agents against enterococci. Antimicrobial Agents and Chemotherapy. 40:1996;1745-1747.
4. Ford C.W., Hamel J.C., Wilson D.M., Moerman J.K., Stapert D., Yancey R.J. Jr, Hutchinson D.K., Barbachyn M.R., Brickner S.J. In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections. Antimicrobial Agents & Chemotherapy. 40:1996;1508-1513.
5. Hayden M.K., Trenholme G.M., Schultz J.E., Sahm D.F. In vivo development of teicoplanin resistance in a vanB Enterococcus faecium isolate. J Infect Dis. 167:1993;1224-1227.
6. Jorgensen J.H., McElmeel M.L., Trippy C.W. In vitro activities of the oxazolidinone antibiotics U-100592 and U-100766 against Staphylococcus aureus and coagulase-negative Staphylococcus species. Antimicrobial Agents & Chemotherapy. 41:1997;465-467.
7. Mason E.O. Jr, Lamberth L.B., Kaplan S.L. In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae. Antimicrobial Agents & Chemotherapy. 40:1996;1039-1040.
8. Mulazimoglu L., Drenning S.D., Yu V.L. In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidis. Antimicrobial Agents and Chemotherapy. 40:1996;2428-2430.
9. Methods for determining bactericidal activity of antimicrobial agents; tentative guideline. 1992;National Committee for Clinical Laboratory Standards, Villanova, PA.
10. Performance standards for antimicrobial susceptibility testing. M7-A4. 1997;National Committee for Clinical Laboratory Standards, Villanova, PA.
11. Noble W.C., Virani Z., Cree R.G. Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus. FEMS Microbiol Lett. 72:1992;195-198.
12. Patel R., Rouse M.S., Piper K.E., Cockerill F.R., Steckelberg J.M. In vitro activity of LY333328 against vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae. Diagnostic Microbiology and Infectious Diseases. 30:1998;89-92.
13. Patel R., Uhl J.R., Kohner P., Hopkins M.K., Cockerill F.R. Multiplex PCR detection of vanA, vanB, vanC-1 and vanC-2/3 genes in enterococci. Journal of Clinical Microbiology. 35:1997;703-707.
14. Rybak M.J., Cappelletty D.M., Moldovan T., Aeschlimann J.R., Kaatz G.W. Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Enterococcus faecium. Antimicrobial Agents & Chemotherapy. 42:1998;721-724.
15. Sahm D.F., Free L., Handwerger S. Inducible and constitutive expression of vanC-1-encoded resistance to vancomycin in Enterococcus gallinarum. Antimicrob Agents Chemother. 39:1995;1480-1484.
16. Spangler S.K., Jacobs M.R., Appelbaum P.C. Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci. Antimicrobial Agents & Chemotherapy. 40:1996;481-484.
17. Zurenko G.E., Yagi B.H., Schaadt R.D., Allison J.W., Kilburn J.O., Glickman S.E., Hutchinson D.K., Barbachyn M.R., Brickner S.J. In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents. Antimicrobial Agents & Chemotherapy. 40:1996;839-845.