MigA, a quorum-responsive gene of Pseudomonas aeruginosa, is highly expressed in the cystic fibrosis lung environment and modifies low-molecular-mass lipopolysaccharide

Microbiology

Volumn 146, Issue 10, 2000, Pages 2509-2519

  Yang, H ^a   Matewish, M ^a   Loubens, I ^a   Storey, D G ^a   Lam, J S ^a   Jin, S ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

LPS and quorum response; MigA; Mucus

Indexed keywords

BACTERIAL ENZYME; BACTERIUM LIPOPOLYSACCHARIDE; BETA GALACTOSIDASE; CORE PROTEIN; GLYCOSYLTRANSFERASE; O ANTIGEN; VIRULENCE FACTOR;

ADAPTATION; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL MUTATION; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BRONCHUS MUCUS; CARBOHYDRATE ANALYSIS; CARBOHYDRATE METABOLISM; CHILD; CLINICAL ARTICLE; CYSTIC FIBROSIS; ENVIRONMENT; ENZYME INDUCTION; GENE DELETION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; GRAM NEGATIVE INFECTION; HOMEOBOX; HUMAN; HUMAN TISSUE; MUCUS SECRETION; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOMONAS AERUGINOSA; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; SURVIVAL; TRANSCRIPTION REGULATION;

PSEUDOMONAS AERUGINOSA;

EID: 0033753958     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-146-10-2509     Document Type: Article

References (60)

1. Functional analysis of genes responsible for the synthesis of the B-band O antigen of Pseudomonas aeruginosa serotype O6 lipopolysaccharide
2. Infections caused by Pseudomonas aeruginosa
3. Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family
4. Altered carbohydrate composition of salivary mucins from patients with cystic fibrosis and the adhesion of Pseudomonas aeruginosa
5. Cloning of Pseudomonas aeruginosa algG, which controls alginate structure
6. 12
7. Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis
8. A highly sensitive periodic acid-silver stain for 1,2-diol groups of glycoproteins and polysaccharides in polyacrylamide gels
9. Diverse VH and V kappa genes encode antibodies to Pseudomonas aeruginosa LPS
10. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa
11. Self perception in bacteria: Quorum sensing with acylated homoserine lactones
12. Microbiology of airway disease in patients with cystic fibrosis
13. Alginate biosynthesis and unusual characteristics associated with the pathogenesis of Pseudomonas aeruginosa in cystic fibrosis
14. Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia
15. Studies on transformation of Escherichia coli with plasmids
16. Outer membrane of Pseudomonas aeruginosa: Heat- And 2-mercaptoethanol-modifiable proteins
17. Pseudomonas aeruginosa isolates from patients with cystic fibrosis: A class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains
18. The assembly system for the outer core portion of R1- and R4-type lipopolysaccharides of Escherichia coli. The R1 core-specific beta-glucosyltransferase provides a novel attachment site for O-polysaccharides
19. Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels
20. Pseudomonas aeruginosa virulence-associated factors and their role in burn wound infections
21. Chromosomal genetics of Pseudomonas
22. Nucleotide sequence of the rpoN gene and characterization of two downstream open reading frames in Pseudomonas aeruginosa
23. Monoclonal antibodies that distinguish inner core, outer core, and lipid A regions of Pseudomonas aeruginosa lipopolysaccharide
24. Rapid and efficient site-specific mutagenesis without phenotypic selection
25. Occurrence of a common lipopolysaccharide antigen in standard and clinical strains of Pseudomonas aeruginosa
26. Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1
27. A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS
28. Increased resolution of lipopolysaccharides and lipooligosaccharides utilizing tricine-sodium dodecyl sulfate-poly-acrylamidegel electrophoresis
29. Avirulence and altered physiological properties of cystic fibrosis strains of Pseudomonas aeruginosa
30. Phosphorylation-independent activity of the response regulators AlgB and AlgR in promoting alginate biosynthesis in mucoid Pseudomonas aeruginosa
31. Nonmotility and phagocytic resistance of Pseudomonas aeruginosa isolates from chronically colonized patients with cystic fibrosis
32. Interaction between Pseudomonas aeruginosa and host defenses in cystic fibrosis
33. Products of three accessory genes, pilB, pilC, and pilD, are required for biogenesis of Pseudomonas aeruginosa pili
34. Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
35. Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
36. Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication
37. Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes
38. A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa
39. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes
40. The chain of command in Pseudomonas quorum sensing
41. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa
42. Immunohistologic quantification of Pseudomonas aeruginosa in the tracheobronchial tree from patients with cystic fibrosis
43. Involvement of the rml locus in core oligosaccharide and O polysaccharide assembly in Pseudomonas aeruginosa
44. Genetics of O-antigen biosynthesis in Pseudomonas aeruginosa
45. Structural characterization of the outer core and the O-chain linkage region of lipopolysaccharide from Pseudomonas aeruginosa serotype O5
46. Nucleotide sequence and expression in Escherichia coli of the Pseudomonas aeruginosa lasA gene
47. Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: An autoinduction regulatory hierarchy
48. Population transcript accumulation of Pseudomonas aeruginosa exotoxin A and elastase in sputa from patients with cystic fibrosis
49. Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis
50. Pseudomonas aeruginosa lasR transcription correlates with the transcription of lasA, lasB, and toxA in chronic lung infections associated with cystic fibrosis
51. Pseudomonas aeruginosa LasA: A second elastase under the transcriptional control of lasR
52. lasA and lasB genes of Pseudomonas aeruginosa: Analysis of transcription and gene product activity
53. Characterization of the type a flagellin gene from Pseudomonas aeruginosa PAK
54. A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels
55. Isolation and characterization of Pseudomonas aeruginosa genes inducible by respiratory mucus derived from cystic fibrosis patients
56. Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa
57. Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa
58. Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical sites
59. Transcriptional analysis of the Pseudomonas aeruginosa genes algR, algB, and algD reveals a hierarchy of alginate gene expression which is modulated by algT