Growth hormone increases connexin-43 expression in the cerebral cortex and hypothalamus

Endocrinology

Volumn 141, Issue 10, 2000, Pages 3879-3886

  Äberg, N David ^a   Carlsson, Björn ^b   Rosengren, Lars ^a   Oscarsson, Jan ^a   Isaksson, Olle G P ^b   Rönnbäck, Lars ^a   Eriksson, Peter S ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; HYDROCORTISONE SODIUM SUCCINATE; LEVOTHYROXINE; MESSENGER RNA; RECOMBINANT GROWTH HORMONE; RECOMBINANT SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; HORMONE ACTION; HYPOPHYSECTOMY; HYPOTHALAMUS; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; RAT; RNA ANALYSIS; WESTERN BLOTTING;

EID: 0033745138     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.10.7731     Document Type: Article

References (61)

1. Mode of action of pituitary growth hormone on target cells
2. The anterior pituitary
3. Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency
4. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH
5. Modulation of long-term memory and extinction responses induced by growth hormone (GH) and growth hormone releasing hormone (GHRH) in rats
6. Microcephalic cerebrum with hypomyelination in the growth hormone-deficient mouse (lit)
7. Systemic administration of recombinant human growth hormone induces expression of the c-fos gene in the hypothalamic arcuate and periventricular nuclei in hypophysectomized rats
8. Effects of growth hormone on brain biogenic amine levels
9. Treatment of growth hormone-deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluid and affects neurotransmitters
10. Localization and ontogeny of growth hormone receptor gene expression in the central nervous system
11. Growth hormone induces somatostatin and insulin like growth factor I gene expression in the cerebral hemispheres of aging rats
12. Regulation of insulin-like growth factor I (IGF-I) gene expression in brain of transgenic mice expressing an IGF-I-luciferase fusion gene
13. Uptake of circulating insulin-like growth factor-I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rat brain
14. IGF-I gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
15. Gap junctions in the brain: Where, what type, how many and why?
16. Connexin30 in rodent, cat and human brain: Selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance
17. Cloning of a new gap junction gene (Cx36) highly expressed in mammalian brain neurons
18. Changes in the properties of gap junctions during neuronal differentiation of hippocampal progenitor cells
19. Distribution of mRNAs coding for liver and heart gap junction proteins in the rat central nervous system
20. Coexpression of connexin45 and -32 in oligodendrocytes of rat brain
21. Diverse functions of vertebrate gap junctions
22. Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke
23. Circumstantial evidence for a role of the secretory pattern of growth hormone in control of body growth
24. Effect of thyroxine and growth hormone on longitudinal bone growth in the hypophysectomized rat
25. GH but not IGF-I or insulin increases lipoprotein lipase activity in muscle tissues of hypophysectomised rats
26. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
27. Comparison of extraction methods for insulin-like growth factor-binding proteins prior to measurement of insulin-like growth factor-I in undernourished neonatal and adult rat serum
28. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
29. Extent of intercellular calcium wave propagation is related to gap junction permeability and level of connexin43 expression in astrocytes in primary cultures from four brain regions
30. Counexin43: A protein from rat heart homologous to a gap junction protein from liver
31. Connexin43 mRNA and protein expression during postnatal development of defined brain regions
32. Regulation of insulin-like growth factor-I gene expression by growth hormone
33. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
34. Gap junctions between cultured astrocytes: Immunocytochemical, molecular, and electrophysiological analysis
35. Antisera directed against connexin 43 peptides react with a 43-kD protein localized to gap junction in myocardium and other tissues
36. Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF
37. Databases on transcriptional regulation: TRANSFAC, TRRD, and COMPEL
38. Growth hormone (GH) immunoreactivity in the rodent and primate CNS: Distribution, characterization and presence posthypophysectomy
39. Insulin-like growth factor-1 attenuates apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats
40. Heterogeneity in gap junction expression in astrocytes cultured from different brain regions
41. Growth hormone secretion in the rat: Metabolic clearance and secretion rates
42. Imprinting of growth hormone secretion, body growth, and hepatic steroid metabolism by neonatal testosterone
43. In situ hybridization to rat brain and pituitary gland of growth hormone cDNA
44. Growth hormone and somatostatin gene expression in adult and aging rats as measured by quantitative in situ hybridization
45. Neural expression of the pituitary GH gene
46. Growth hormone (GH), thyroid-stimulating hormone (TSH), and luteinizing hormone (LH)-like peptides in the rodent brain: Non-parallel ontogenetic development with pituitary counterparts
47. Biologically active pituitary hormones in the rat brain amygdaloid nucleus
48. Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats
49. 125I-human growth hormone: Evidence for a prolactin 'short-loop' feedback site
50. Cellular localization of the growth hormone binding protein in the rat
51. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
52. Normal growth and development in the absence of hepatic insulin-like growth factor I
53. Characterization of somatomedins from human fetal brain: Identification of a variant form of insulin-like growth factor I
54. Des(1-3)IGF-I: A truncated form of insulin-like growth factor-I
55. Enzymatic conversion of IGF-I to des(1-3)IGF-I in rat serum and tissues: A further potential site of growth hormone regulation of IGF-I action
56. Regulation of gonadotropin-releasing hormone (GnRH) gene expression by insulin-like growth factor I in a cultured GnRH-expressing neuronal cell line
57. Early responses of trans-activating factors to growth hormone in preadipocytes: Differential regulation of CCAAT enhancer-binding protein-beta (C/EBPβ) and C/EBPδ
58. Expression of connexin43 mRNA in adult rodent brain
59. Gap junctions in the adult cerebral cortex: Regional differences in their distribution and cellular expression of connexins
60. Grid-mapped freeze-fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a 'panglial syncytium' that is not coupled to neurons
61. Evidence for glutamate-mediated activation of hippocampal neurons by glial calcium waves