In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

Volumn 41, Issue 1, 2000, Pages 992-993

  Yoo, Hyuk Sang ^a   Park, Tae Gwan ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC POLYMERS; BIOPOLYMERS; COPOLYMERS; DRUG PRODUCTS; ESTERS; LIVING SYSTEMS STUDIES; MICROSCOPIC EXAMINATION; NANOSTRUCTURED MATERIALS; ONCOLOGY; PHYSIOLOGY; SURFACE PHENOMENA;

ANTI-TUMOR ACTIVITIES; DOXORUBICIN; POLYGLYCOLIC ACID; POLYLACTIC ACID;

POLYMER BLENDS;

EID: 0033734338     PISSN: 00323934     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Article

References (6)

1. Duncan, R. Drug-polymer conjugates: potential for improved chemotherapy Anti-cancer Drugs 1992, 3, 175.
2. Minko, T., Kopeckova, P., Pozharov, V.; Kopecek, J HPMA copolmer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line. J. Control Release 1998, 54, 223
3. Omelyanenko, V.; Kopeckova, P., Gentry, C.; Kopecek, J. Targetable HPMA copolymer-adriamycin conjugates Recognition, internalization, and subcellular fate. J Control Release 1998, 53, 25.
4. Yokoyama, M.; Kwon, G.S ; Okano, T ; Sakurai, Y ; Seto, T ; Kataoka, K. Preparation of micelle-forming polymer-drug conjugates Bioconjugate Chem. 1992, 3, 295.
5. Yoo, H S ; Oh, J. E.; Lee, K H , Park, T G. Biodegradable Nanoparticles Containing Doxorubicin-PLGA Conjugate for Sustained Release. Pharm. Res 1999. 16, 1114.
6. Park, T.G. Degradation of poly(D,L-lactic)microsphere: effect of molecular weight. J Controlled Release 1994, 30, 161.