Retrospective analysis of the frequency and recognition of adverse drug reactions by means of automatically recorded laboratory signals

British Journal of Clinical Pharmacology

Volumn 47, Issue 5, 1999, Pages 557-564

  Tegeder, I ^a   Levy, M ^a   Muth Selbach, U ^a   Oelkers, R ^b   Neumann, F ^b   Dormann, H ^a   Azaz Livshits, T ^a   Criegee Rieck, M ^c   Schneider, H T ^c   Hahn, E G ^d   Brune, K ^c   Geisslinger, G ^d  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c GOETHE UNIVERSITY   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Adverse drug reactions; Automated laboratory signals

Indexed keywords

ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CARDIOVASCULAR AGENT; DIGOXIN; DIURETIC AGENT; FUROSEMIDE; GLIBENCLAMIDE; INSULIN; LOW MOLECULAR WEIGHT HEPARIN; NIFEDIPINE; POTASSIUM CHLORIDE;

ADULT; AGED; ARTICLE; AUTOMATION; DATA ANALYSIS; DIAGNOSTIC VALUE; DRUG INDUCED DISEASE; FEMALE; HEPATITIS; HOSPITALIZATION; HUMAN; HYPERKALEMIA; HYPOGLYCEMIA; HYPOKALEMIA; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; THROMBOCYTOPENIA;

ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; DRUG MONITORING; DRUG THERAPY; FEMALE; HEMATOLOGIC TESTS; HUMANS; KIDNEY; KIDNEY DISEASES; LIVER; LIVER DISEASES; MALE; MEDICAL RECORDS; MIDDLE AGED; PHARMACEUTICAL PREPARATIONS; PHYSICIAN'S ROLE; RETROSPECTIVE STUDIES;

EID: 0032922810     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1999.00926.x     Document Type: Article

References (33)

1. Brennan TA, Lcapc LL, Laird NM, et al. Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study. N EnglJ Med 1991; 324: 370-376.
2. Lindquist R, Gersema LM. Understanding and preventing adverse drug events [In Process Citation]. AACN Clin Issues 1998; 9: 119-128.
3. Jick H. Adverse drug reactions: the magnitude of the problem. J AUergy Clin Iinmnnol 1984; 74: 555-557.
4. Mitchell AA, Goldman P, Shapiro S, Slone D. Drug utilization and reported adverse reactions in hospitalized children. Am J Epidemiol 1979; 110: 196-204.
5. Leape LL, Drennan TA, Laird N, et al. The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N EnglJ Med 1991; 324: 377-384.
6. Bates DW, Cullen DJ, Laird N, et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA 1995; 274: 29-34.
7. Evans RS, Classen DC, Stevens LE, et al. Using a hospital information system to assess the effects of adverse drug events. Proc Annu Syinp Compnt Appl Med Care 1993; 00: 161-165.
8. Karch FE, Lasagna L. Adverse drug reactions. A critical review. JA MA 1975; 234: 1236-1241.
9. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 1998; 279: 1200-1205.
10. Dartnell JG, Anderson RP, Chohan V, et al. Hospitalisation for adverse events related to drug therapy: incidence, avoidability and costs. MedJ Aust 1996; 164: 659-662.
11. Miller RR. Hospital admissions due to adverse drug reactions. A report from the Boston Collaborative Drug Surveillance Program. Arch Intern Med 1974; 134: 219-223.
12. Azaz-Livshits T, Levy M, Sadan B, Shalit M, Geisslinger G, Brune K. Computerized surveillance of adverse drug reactions in hospital: pilot study. BrJ Clin Pliannacol 1998; 45: 309-314.
13. Johnson JA, Bootman JL. Drug-related morbidity and mortality. A cost-of-illness model. Arch Intern Med 1995; 155: 1949-1956.
14. Bates DW, Spell N, Cullen DJ, et al The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group. JA MA 1997; 277: 307-311.
15. Anderson JG, Jay SJ, Anderson M, Hunt TJ. Evaluating the potential effectiveness of using computerized information systems to prevent adverse drug events. Proc AMIA Annu Fall Symp 1997: 228-232.
16. Strom B. Drug epidemiology and post marketing surveillance. (1 ed.) New York: Plenum Publishing Corporation, 1992.
17. Classen DC, Pestotnik SL, Evans RS, Burke JP. Computerized surveillance of adverse drug events in hospital patients [published erratum appears in JAMA 1992 Apr 8;267:1922]. JAMA 1991; 266: 2847-2851.
18. Evans RS, Pestotnik SL, Classen DC, et al. Development of a computerized adverse drug event monitor. Proc Annn Symp Compnt Appl Med Care 1991: 23-27.
19. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pliannacol Tlier 1981; 30: 239-245.
20. Koch-Weser J, Sellers EM, Zacest R. The ambiguity of adverse drug reactions. EtirJ Clin Pliannacol 1977; 11: 75-78.
21. Krämer MS, Leventhal JM, Hutchinson TA, Fcinstein AR. An algorithm for the operational assessment of adverse drug reactions. I. Background, description, and instructions for use. JA MA 1979; 242: 623-632.
22. Bates DW, AC ON, Boyle D, et al. Potential identifiability and preventability of adverse events using information systems. J Am Mcd Inform Assoc 1994; 1: 404-411.
23. Rawlins MD. Clinical pharmacology. Adverse reactions to drugs. BrMedJ 1981; 282: 974-976.
24. Rieder MJ. Mechanisms of unpredictable adverse drug reactions. Dntg saf 1994; 11: 196-212.
25. Naranjo CA, Lanctot KL, Lane DA. The Bayesian differential diagnosis of neutropenia associated with antiarrhythmic agents. J Clin Pliannacol 1990; 30: 1120-1127.
26. Naranjo CA, Lane D, Ho-Asjoe M, Lanctot KL. A Bayesian assessment of idiosyncratic adverse reactions to new drugs: Guillain-Barre syndrome and zimeldine.J Clin Pliannacol 1990; 30: 174-180.
27. Lesar TS, Lomaestro BM, Pohl H. Medication-prescribing errors in a teaching hospital. A 9-year experience. Arch Intent Mcd 1997; 157: 1569-1576.
28. Ouslander JG. Drug therapy in the elderly. Ann Intern Mcd 1981; 95: 711-722.
29. Mannesse CK, Derkx FH, de Ridder MA, Man in 't Veld AJ, van der Cammen TJ. Adverse drug reactions in elderly patients as contributing factor for hospital admission: cross sectional study. BrMedJ 1997; 315: 1057-1058.
30. Gray SL, Sager M, Lestico MR, Jalaluddin M. Adverse drug events in hospitalized elderly. J Gerontol A Biol Sei Med Sei 1998; 53: M59-63.
31. Walker J, Wynne H. Review: the frequency and severity of adverse drug reactions in elderly people. Age Ageing 1994; 23: 255-259.
32. Stewart RB, Cooper JW. Polyphannacy in the aged. Practical solutions. Dntgs Aging 1994; 4: 449-461.
33. Levy M, Azaz-Livshits T, Sadan B, Shalit M, Geisslinger G, Brune K. Computerized surveillance of adverse drug reactions in hospital: implementation. EnrJ Clin Pliannacol 1999; (in press).