Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF

Developmental Biology

Volumn 216, Issue 2, 1999, Pages 521-534

  Pispa, Johanna ^a   Jung, Han Sung ^a   Jernvall, Jukka ^a   Kettunen, Päivi ^a   Mustonen, Tuija ^a   Tabata, Makoto J ^a   Kere, Juha ^b   Thesleff, Irma ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Ectodermal dysplasia; Enamel knot; Epithelial mesenchymal interactions; TNF; Tumor necrosis factor

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECTODERMAL DYSPLASIA; EMBRYO; EMBRYO PATTERN FORMATION; ENAMEL; MESENCHYME; MOLAR TOOTH; MORPHOGENESIS; MOUSE MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TISSUE INTERACTION; TOOTH MALFORMATION;

ANIMALIA;

EID: 0033572260     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9514     Document Type: Article

References (51)

1. Bayes M., Hartung A. J., Ezer S., Pispa J., Thesleff I., Srivastava A. K., Kere J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Mol. Genet. 7:1998;1661-1669.
2. Bei M., Maas R. FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development. 125:1998;4325-4333.
3. Bellusci S., Furuta Y., Rush M. G., Henderson R., Winnier G., Hogan B. L. M. Involvement of Sonic Hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development. 124:1997;53-63.
4. Blecher S. R. Anhidrosis and absence of sweat glands in mice hemizygous for the Tabby gene: Supportive evidence for the hypothesis of homology between Tabby and human anhidrotic (hypohidrotic) ectodermal dysplasia (Christ-Siemens-Touraine syndrome). J. Invest. Dermatol. 87:1986;720-722.
5. Blecher S. R., Debertin M., Murphy J. S. Pleiotropic effect of Tabby gene on epidermal growth factor-containing cells of mouse submandibular gland. Anat. Rec. 207:1983;25-29.
6. Blecher S. R., Kapalanga J., Lalonde D. Induction of sweat glands by epidermal growth factor in murine X-linked anhidrotic ectodermal dysplasia. Nature. 345:1990;542-544.
7. Bushdid P. B., Brantley D. M., Yull F. E., Blaeuer G. L., Hoffman L. H., Niswander L., Kerr L. D. Inhibition of NF-kappa B activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis [see comments]. Nature. 392:1998;615-618.
8. Chuong C.-M. Molecular Basis of Epithelial Appendage Morphogenesis. 1998;R. G. Landes, Austin.
9. Claxton J. H. The initiation and development of the hair follicle population in tabby mice. Genet. Res. 10:1967;161-171.
10. Dassule H. R., McMahon A. P. Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev. Biol. 202:1998;215-227.
11. Ezer S., Bayés M., Elomaa O., Schlessinger D., Kere J. Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and colocalizes with cytoskeletal structures at lateral and apical surfaces of cells. Hum. Mol. Genet. 8:1999;2079-2086.
12. Falconer D. S. A totally sex-linked gene in the house mouse. Nature. 169:1952;664-665.
13. Ferguson B. M., Brockdorff N., Formstone E., Ngyuen T., Kronmiller J. E., Zonana J. Cloning of Tabby, the murine homolog of the human EDA gene - Evidence for a membrane-associated protein with a short collagenous domain. Hum. Mol. Genet. 6:1997;1589-1594.
14. Ferguson C. A., Tucker A. S., Christensen L., Lau A. L., Matzuk M. M., Sharpe P. T. Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev. 12:1998;2636-2649.
15. Gene expression in tooth (WWW database), 1999, http://honeybee. helsinki. fi/toothexp , Developmental Biology Programme of the University of Helsinki.
16. Gruss H. J., Dower S. K. Tumor necrosis factor ligand superfamily: Involvement in the pathology of malignant lymphomas. Blood. 85:1995;3378-3404.
17. Grüneberg H. Genes and genotypes affecting the teeth of the mouse. J. Embryol. Exp. Morphol. 14:1965;137-159.
18. Grüneberg H. The glandular aspects of the tabby syndrome in the mouse. J. Embryol. Exp. Morphol. 25:1971;1-19.
19. Headon D., Overbeek P. A. Involvement of a novel Tnf receptor homologue in hair follicle induction. Nature Genet. 22:1999;370-374.
20. Heikinheimo M., Lawshe A., Shackleford G. M., Wilson D. B., MacArthur C. A. Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system. Mech. Dev. 48:1994;129-138.
21. Henrique D., Adam J., Myat A., Chitnis A., Lewis J., Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature. 375:1995;787-790.
22. Hogan B. L. Morphogenesis. Cell. 96:1999;225-233.
23. Jernvall J., Kettunen P., Karavanova I., Martin L. B., Thesleff I. Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: Non-dividing cells express growth stimulating Fgf-4 gene. Int. J. Dev. Biol. 38:1994;463-469.
24. Jernvall J., Thesleff I. Iterative signaling and patterning during mammalian tooth moprhogenesis. Mech. Dev. 1999.
25. Jernvall J., Åberg T., Kettunen P., Keränen S., Thesleff I. The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development. 125:1998;161-169.
26. Kere J., Srivastava A. K., Montonen O., Zonana J., Thomas N., Ferguson B., Munoz F., Morgan D., Clarke A., Baybayan P., Chen E. Y., Ezer S., Saarialho-Kere U., de la Chapelle A., Schlessinger D. X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nature Genet. 13:1996;409-416.
27. Kettunen, P, Itoh, N, and, Thesleff, I. 1999, Associations of FGF-3 and FGF-10 with signalling networks regulating tooth morphogenesis. Submitted for publication.
28. Kettunen P., Karavanova I., Thesleff I. Responsiveness of developing dental tissues to fibroblast growth factors - Expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4 - And stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev. Genet. 22:1998;374-385.
29. Kettunen P., Thesleff I. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev. Dynam. 211:1998;256-268.
30. Kindred B. Some observations on the skin and hair of tabby mice. J. Hered. 58:1967;197-199.
31. Kollar E. J., Baird G. R. Tissue interactions in embryonic mouse tooth germs. II. The inductive role of the dental papilla. J. Embryol. Exp. Morphol. 24:1970;173-186.
32. Lacey D. L., Timms E., Tan H. L., Kelley M. J., Dunstan C. R., Burgess T., Elliott R., Colombero A., Elliott G., Scully S., Hsu H., Sullivan, Hawkins N., Davy E., Capparelli C., Eli A., Qian Y. X., Kaufman S., Sarosi, Shalhoub V., Senaldi G., Guo J., Delaney J., Boyle W. J. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 93:1998;165-176.
33. Luckett W. P. Superordinal and intraordinal affinities of rodents: Developmental evidence from the dentition and placentation. Luckett W. P., Hartenberger J.-L. Evolutionary Relationships among Rodents. 1985;227-276 Plenum, New York.
34. Mikkola M. L., Pispa J., Pekkanen M., Paulin L., Nieminen P., Kere J., Thesleff I. Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion. Mech. Dev. 1999.
35. Montonen O., Ezer S., Saarialho-Kere U. K., Herva R., Karjalainen-Lindsberg M. L., Kaitila I., Schlessinger D., Srivastava A. K., Thesleff I., Kere J. The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone. J. Histochem. Cytochem. 46:1998;281-289.
36. Partanen A. M., Ekblom P., Thesleff I. Epidermal growth factor inhibits morphogenesis and cell differentiation in cultured mouse embryonic teeth. Dev. Biol. 111:1985;84-94.
37. Peters H., Balling R. Teeth - Where and how to make them. Trends Genet. 15:1999;59-65.
38. Smith C. A., Farrah T., Goodwin R. G. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death. Cell. 76:1994;959-962.
39. Sofaer J. A. Aspects of the tabby-crinkled-downless syndrome. I. The development of tabby teeth. J. Embryol. Exp. Morphol. 22:1969;181-205.
40. Srivastava A. K., Pispa J., Hartung A. J., Du Y., Ezer S., Jenks T., Shimada T, Pekkanen M., Mikkola M. L., Ko M. S., Thesleff I., Kere J., Schlessinger D. The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains. Proc. Natl. Acad. Sci. USA. 94:1997;13069-13074.
41. Takuma N., Sheng H. Z., Furuta Y., Ward J. M., Sharma K., Hogan BL, Pfaff S. L., Westphal H., Kimura S., Mahon K. A. Formation of Rathke's pouch requires dual induction from the diencephalon. Development. 125:1998;4835-4840.
42. Thesleff I., Jernvall J. The enamel knot - A putative signaling center regulating tooth development. Cold Spring Harb. Symp. Quant. Biol. 62:1997;257-267.
43. Thesleff I., Sharpe P. Signalling networks regulating dental development. Mech. Dev. 67:1997;111-123.
44. Thesleff I., Vaahtokari A., Partanen A. M. Regulation of organogenesis: Common molecular mechanisms regulating the development of teeth and other organs. Int. J. Dev. Biol. 39:1995;35-50.
45. Vaahtokari A., Åberg T., Jernvall J., Keränen S., Thesleff I. The enamel knot as a signaling center in the developing mouse tooth. Mech. Dev. 54:1996;39-43.
46. Vainio S., Karavanova I., Jowett A., Thesleff I. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell. 75:1993;45-58.
47. Vargas G. A., Fantino E., George-Nascimento C., Gargus J. J. X., Haigler H. T. Reduced epidermal growth factor receptor expression in hypohidrotic ectodermal dysplasia and Tabby mice. J. Clin. Invest. 97:1996;2426-2432.
48. Widelitz R. B., Jiang T. X., Noveen A., Chen C. W., Chuong C. M. FGF induces new feather buds from developing avian skin. J. Invest. Dermatol. 107:1996;797-803.
49. Wilkinson D., Green J. In situ hybridization and the three-dimensional reconstruction of serial sections. Copp A. J., Cole D. E. Postimplantation Mammalian Embryos. 1990;155-171 Oxford Univ. Press, London.
50. Wilkinson D. G., Peters G., Dickson C., McMahon A. P. Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J. 7:1988;691-695.
51. Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S., Tomoyasu A., Yano K., Goto M., Murakami A., Tsuda E., Morinaga, Higashio K., Udagawa N., Takahashi N., Suda T. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA. 95:1998;3597-3602.