The quarternary molecular architecture of TetA, a secondary tetracycline transporter from Escherichia coli

Molecular Microbiology

Volumn 38, Issue 3, 2000, Pages 482-492

  Yin, Chang Cheng ^a   Aldema Ramos, Mila L ^b,c   Ines Borges Walmsley, M ^c   Taylor, Robert W ^a   Walmsley, Adrian R ^c   Levy, Stuart B ^b,c   Bullough, Per A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; HISTIDINE; LIPID; MALTOSE; PROTEIN TETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; ELECTRON MICROSCOPY; ESCHERICHIA COLI; IMAGE ANALYSIS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; PROTON TRANSPORT;

ANTIPORTERS; BACTERIAL PROTEINS; CRYSTALLIZATION; ESCHERICHIA COLI; HISTIDINE; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROSCOPY, ELECTRON; PROTEIN STRUCTURE, QUATERNARY;

EID: 0033678885     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.02149.x     Document Type: Article

References (41)

1. Purification of the Tn10-specified tetracycline efflux antiporter TetA in a native state as a polyhistidine fusion protein
2. Membrane topology of the pBR322 tetracycline resistance protein: TetA-PhoA gene fusions and implications for the mechanisms of TetA membrane insertions
3. MRC image processing programs
4. Intracistronic complementation of the membrane protein of Tn10
5. Human erythrocyte band 3. Solubilization and reconstitution into two-dimensional crystals
6. Topology of the transposon Tn10-encoded tetracycline resistance protein within the inner membrane of E. coli
7. Mutations in the tetA(B) gene that cause a change in substrate specificity of the tetracycline efflux pump
8. Glucose transporter oligomeric structure determines transport function-reversible redox-dependent interconversions of tetrameric and dimeric GLUT1
9. Similarity measures between images
10. Classification of very large electron microscopical image data sets
11. Use of multivariate statistical analysis in analysing the images of biological macromolecules
12. IMAGIC: A fast, flexible and friendly image analysis software system
13. Structure of purple membrane from Halobacterium halobium: Recording, measurement and evaluation of electron micrographs at 3.5 Å resolution
14. Evidence that Tet protein functions as a multimer in the inner membrane of E. coli
15. The orientation of porin OmpF in the outer membrane of Escherichia coli
16. 2D crystallization: From art to science
17. From membrane to molecule to the third amino acid from the left with a membrane transport protein
18. Energetics of tetracycline efflux system encoded by Tn10 in E. coli
19. + antiporter of Escherichia coli is essential for substrate binding
20. + antiporter reveals a transmembrane water-filled channel
21. Two-dimensional crystallization of membrane proteins
22. Evolution and spread of tetracycline resistance determinants
23. The NH2-terminal half of the Tn10-specified tetracycline efflux protein TetA contains a dimerization domain
24. Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in E. coli
25. Penetration of lipophilic agents with multiple protonation sites into bacterial cells: Tetracyclines and fluoroquinolones as examples
26. Microbial genome analyses: Global comparison of transport capabilities based on phylogenies, bioenergetics and substrate specificities
27. Bio-beads: An efficient strategy for two-dimensional crystallization of membrane proteins
28. Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis
29. Interdomain hybrid Tet proteins confer tetracycline resistance only when they are derived from closely related members of the Tet gene family
30. Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli
31. +/glucose cotransporter functions in situ as a homotetramer
32. Analysis of electron microscope images and electron diffraction patterns of thin crystals of 29 connectors in ice
33. + chelate chromatography of the IIBC(Glc) subunit
34. Projection structures of three photosynthetic complexes from Rhodobacter sphaeroides: LH2 at 6 Å, LH1 and RC-LH1 at 25 Å
35. Two-dimensional structure of the membrane domain of human band 3, the anion transport protein of erythrocyte membrane
36. Three-dimensional map of the dimeric membrane domain of human erythrocyte anion exchanger, band 3
37. Three-dimensional structure of the ion-coupled transport protein NhaA
38. Projection structure of NhaA, a secondary transporter from Escherichia coli, at 4.0 Å resolution
39. Transport of divalent cations with tetracycline as mediated by the transposon Tn10 encoded tetracycline resistance protein
40. + antiport mediated by transposon Tn10 encoded tetracycline resistance protein in E. coli
41. Two-dimensional crystallization of Escherichia coli lactose permease