Use of amifostine as a chemoprotectant during high-dose chemotherapy in autologous peripheral blood stem cell transplantation

Bone Marrow Transplantation

Volumn 26, Issue 11, 2000, Pages 1247-1249

  Cronin, S ^a   Uberti, J P ^b   Ayash, L J ^b   Raith, C ^a   Ratanatharathorn, V ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Amifostine; Autologous peripheral blood stem cell transplantation; Chemoprotectant; Ethyol; Germ cell tumor; WR2721

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; AMIFOSTINE; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; BLEOMYCIN; CARBOPLATIN; CD34 ANTIGEN; CHORIONIC GONADOTROPIN BETA SUBUNIT; CISPLATIN DERIVATIVE; CREATININE; DRUG METABOLITE; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; IFOSFAMIDE; MORPHINE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SODIUM CHLORIDE; THIOL DERIVATIVE; VINBLASTINE;

ADULT; ARTICLE; AUTOTRANSPLANTATION; CANCER CHEMOTHERAPY; CASE REPORT; CHEMOPROPHYLAXIS; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; FEVER; GERM CELL TUMOR; HEARING LOSS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MALE; MUCOSA INFLAMMATION; NEPHROTOXICITY; NEUROPATHY; NEUTROPENIA; OTOTOXICITY; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TINNITUS;

EID: 0033670569     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1702694     Document Type: Article

References (10)

1. Tandem high dose chemotherapy with autologous bone marrow transplantation for initial relapse of testicular germ cell cancer
2. Dose escalation study of high-dose carboplatin and etoposide with autologous marrow support in patients with recurrent and refractory germ cell tumors
3. Clinical status and optimal use of amifostine
4. Amifostine in reducing cisplatin toxicity
5. Amifostine reduces the incidence of cumulative nephrotoxicity from cisplatin: Laboratory and clinical aspects
6. Future development of amifostine in cancer treatment
7. Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor
8. The role of ifosfamide plus cisplatin-based chemotherapy as salvage therapy for patients with refractory germ cell tumors
9. Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer
10. Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors