메뉴 건너뛰기




Volumn 13, Issue 1, 1999, Pages 47-59

Clinical Status and Optimal Use of Amifostine

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; ALKYLATING AGENT; AMIFOSTINE; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CHLORMETHINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DEXAMETHASONE; MERCAPTAMINE; PACLITAXEL; PLATINUM COMPLEX;

EID: 0032933401     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (63)

References (80)
  • 1
    • 0017654698 scopus 로고
    • "Rescue" techniques in cancer chemotherapy: Use of leucovorin and other rescue agents after methotrexate treatment
    • Bertino JR: "Rescue" techniques in cancer chemotherapy: Use of leucovorin and other rescue agents after methotrexate treatment. Semin Oncol 4(2):203-216, 1977.
    • (1977) Semin Oncol , vol.4 , Issue.2 , pp. 203-216
    • Bertino, J.R.1
  • 2
    • 0016803892 scopus 로고
    • Methotrexate distribution in cerebrospinal fluid after intravenous, ventricular, and lumbar infections
    • Shapiro WR: Methotrexate distribution in cerebrospinal fluid after intravenous, ventricular, and lumbar infections. N Engl J Med 293:161, 1975.
    • (1975) N Engl J Med , vol.293 , pp. 161
    • Shapiro, W.R.1
  • 3
    • 0346176227 scopus 로고    scopus 로고
    • Mesnex (mesna)
    • Montvale, New Jersey, Medical Economics
    • Mesnex (mesna), in Arky R (ed): Physician's Desk Reference. Montvale, New Jersey, Medical Economics, 1998.
    • (1998) Physician's Desk Reference
    • Arky, R.1
  • 4
    • 0348067740 scopus 로고    scopus 로고
    • Zinecard (dexrazoxone)
    • Montvale, New Jersey, Medical Economics
    • Zinecard (dexrazoxone) in Arky R (ed): Physician's Desk Reference. Montvale, New Jersey, Medical Economics, 1998.
    • (1998) Physician's Desk Reference
    • Arky, R.1
  • 5
    • 0000416892 scopus 로고
    • Technical papers: Cysteine protection against X irradiation
    • Patt HM, Tyree EB, Straube RL, et al: Technical papers: Cysteine protection against X irradiation. Science 110:213-214, 1949.
    • (1949) Science , vol.110 , pp. 213-214
    • Patt, H.M.1    Tyree, E.B.2    Straube, R.L.3
  • 8
    • 0002852243 scopus 로고
    • Pharmacokinetics of amifostine in cancer patients: Evidence for saturable metabolism
    • Shaw L, Bonner H, Nakashima H, et al: Pharmacokinetics of amifostine in cancer patients: Evidence for saturable metabolism (abstract). Proc Am Soc Clin Oncol 13:144, 1994.
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 144
    • Shaw, L.1    Bonner, H.2    Nakashima, H.3
  • 9
    • 0028127149 scopus 로고
    • Metabolic pathways of WR-2721 (Ethyol, amifostine) in the balb/c mouse
    • Shaw LM, Bonner HS, Brown DQ: Metabolic pathways of WR-2721 (Ethyol, amifostine) in the balb/c mouse. Drug Metab Dispos 22:895-902, 1994.
    • (1994) Drug Metab Dispos , vol.22 , pp. 895-902
    • Shaw, L.M.1    Bonner, H.S.2    Brown, D.Q.3
  • 10
    • 0023679159 scopus 로고
    • Uptake of WR-2721 derivatives by cells in culture: Identification of the transported form of the drug
    • Calabro-Jones PM, Aguilera JA, Ward JF, et al: Uptake of WR-2721 derivatives by cells in culture: Identification of the transported form of the drug. Cancer Res 48:3634-3640, 1988.
    • (1988) Cancer Res , vol.48 , pp. 3634-3640
    • Calabro-Jones, P.M.1    Aguilera, J.A.2    Ward, J.F.3
  • 11
    • 0023793476 scopus 로고
    • Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection
    • Smoluk GD, Fahey RC, Calabro-Jones PM, et al: Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection. Cancer Res 48:3641-3647, 1988.
    • (1988) Cancer Res , vol.48 , pp. 3641-3647
    • Smoluk, G.D.1    Fahey, R.C.2    Calabro-Jones, P.M.3
  • 12
    • 0021914053 scopus 로고
    • Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721
    • Calabro-Jones PM, Fahey RC, Smoluk GD, et al: Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721. Int J Radiat Biol Phys 47:23-27, 1985.
    • (1985) Int J Radiat Biol Phys , vol.47 , pp. 23-27
    • Calabro-Jones, P.M.1    Fahey, R.C.2    Smoluk, G.D.3
  • 13
    • 0346176205 scopus 로고
    • Differential radioprotection of cultured human diploid fibroblasts and fibrosarcoma cells by WR-1065
    • Zhang X, Lai P, Taylor Y: Differential radioprotection of cultured human diploid fibroblasts and fibrosarcoma cells by WR-1065. Radiat Oncol Biol Phys 21:128, 1990.
    • (1990) Radiat Oncol Biol Phys , vol.21 , pp. 128
    • Zhang, X.1    Lai, P.2    Taylor, Y.3
  • 14
    • 0017656527 scopus 로고    scopus 로고
    • Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response
    • Myers CE, McGuire WP, Liss RH, et al: Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response. Science 197:165-167, 1997.
    • (1997) Science , vol.197 , pp. 165-167
    • Myers, C.E.1    McGuire, W.P.2    Liss, R.H.3
  • 15
    • 0023815322 scopus 로고
    • Influence of WR-2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo
    • DeNeve WJ, Everett CK, Suminski JE, et al: Influence of WR-2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo. Cancer Res 48:6002-6005, 1988.
    • (1988) Cancer Res , vol.48 , pp. 6002-6005
    • DeNeve, W.J.1    Everett, C.K.2    Suminski, J.E.3
  • 16
    • 0342820546 scopus 로고
    • Modulation of cisplatin and carboplatin with WR-2721, molecular aspects
    • Treskes M, Holwerda U, Nijtmans L, et al: Modulation of cisplatin and carboplatin with WR-2721, molecular aspects. 7th Conf Chem Mod Cancer Treat , pp 322-323, 1991.
    • (1991) 7th Conf Chem Mod Cancer Treat , pp. 322-323
    • Treskes, M.1    Holwerda, U.2    Nijtmans, L.3
  • 17
    • 0026598335 scopus 로고
    • The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278
    • Treskes M, Holwerda U, Nijtmans LGJ, et al: The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278. Cancer Chemother Pharmacol 29(6):467-470, 1992.
    • (1992) Cancer Chemother Pharmacol , vol.29 , Issue.6 , pp. 467-470
    • Treskes, M.1    Holwerda, U.2    Nijtmans, L.G.J.3
  • 18
    • 0008621385 scopus 로고    scopus 로고
    • Modulation of wild-type p53 protein activity by the aminothiol amifostine
    • El-Ghissassi F, Verhaegh G, Hainaut P: Modulation of wild-type p53 protein activity by the aminothiol amifostine (abstract). Proc Am Soc Clin Oncol 16:543a, 1997.
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • El-Ghissassi, F.1    Verhaegh, G.2    Hainaut, P.3
  • 19
    • 0029745368 scopus 로고    scopus 로고
    • Amifostine: The preclinical basis for broad-spectrum spectrum cytoprotection of normal tissues from cytotoxic therapies
    • Capizzi RL: Amifostine: The preclinical basis for broad-spectrum spectrum cytoprotection of normal tissues from cytotoxic therapies. Semin Oncol 23:2-17, 1996.
    • (1996) Semin Oncol , vol.23 , pp. 2-17
    • Capizzi, R.L.1
  • 20
    • 0023258489 scopus 로고
    • WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
    • Glover D, Glick J, Weiler C, et al: WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma. J Clin Oncol 5(4):574-578, 1987.
    • (1987) J Clin Oncol , vol.5 , Issue.4 , pp. 574-578
    • Glover, D.1    Glick, J.2    Weiler, C.3
  • 21
    • 0022655609 scopus 로고
    • WR-2721 protects against the hematologic toxicity of cyclophosphamide: A controlled phase II trial
    • Glover DJ, Glick JH, Weiler C, et al: WR-2721 protects against the hematologic toxicity of cyclophosphamide: A controlled phase II trial. J Clin Oncol 4:584-588, 1986.
    • (1986) J Clin Oncol , vol.4 , pp. 584-588
    • Glover, D.J.1    Glick, J.H.2    Weiler, C.3
  • 22
    • 0029902007 scopus 로고    scopus 로고
    • Amifostine pretreatment for protection against cyclophosphamide- and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer
    • Kemp G, Rose P, Lurain J, et al: Amifostine pretreatment for protection against cyclophosphamide- and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer. J Clin Oncol 14:2101-2112, 1996.
    • (1996) J Clin Oncol , vol.14 , pp. 2101-2112
    • Kemp, G.1    Rose, P.2    Lurain, J.3
  • 23
    • 0030013080 scopus 로고    scopus 로고
    • Amifostine, cisplatin, and vinblastine in metastatic non-small-cell lung cancer: A report of high response rates and prolonged survival
    • Schiller JH, Storer B, Berlin J, et al: Amifostine, cisplatin, and vinblastine in metastatic non-small-cell lung cancer: A report of high response rates and prolonged survival. J Clin Oncol 14:1913-1921, 1996.
    • (1996) J Clin Oncol , vol.14 , pp. 1913-1921
    • Schiller, J.H.1    Storer, B.2    Berlin, J.3
  • 24
    • 0346176215 scopus 로고    scopus 로고
    • Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer
    • in press
    • Planting AST, Catimel G, de Mulder PHM, et al: Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer. J Clin Oncol, 1998 (in press).
    • (1998) J Clin Oncol
    • Planting, A.S.T.1    Catimel, G.2    De Mulder, P.H.M.3
  • 26
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 16:31-41, 1976.
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 27
    • 0026634982 scopus 로고
    • Improved therapeutic index of carboplatin plus cyclophosphamide vs cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer
    • Alberts DS, Green S, Hannigan EV, et al: Improved therapeutic index of carboplatin plus cyclophosphamide vs cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer. J Clin Oncol 10:706-717, 1992.
    • (1992) J Clin Oncol , vol.10 , pp. 706-717
    • Alberts, D.S.1    Green, S.2    Hannigan, E.V.3
  • 28
    • 0024598398 scopus 로고
    • A comparison of the toxicity and efficacy of cisplatin and carboplatin in advanced ovarian cancer
    • Adams M, Kerby IJ, Rocker I, et al: A comparison of the toxicity and efficacy of cisplatin and carboplatin in advanced ovarian cancer. Acta Oncol 28:57-60, 1989.
    • (1989) Acta Oncol , vol.28 , pp. 57-60
    • Adams, M.1    Kerby, I.J.2    Rocker, I.3
  • 29
    • 0022381486 scopus 로고
    • Ovarian trials at the Royal Marsden
    • Wiltshaw E: Ovarian trials at the Royal Marsden. Cancer Treat Rep 12:67-71, 1985.
    • (1985) Cancer Treat Rep , vol.12 , pp. 67-71
    • Wiltshaw, E.1
  • 30
    • 0023138415 scopus 로고
    • Creatinine clearance as a predictor of ultrafilterable platinum disposition in cancer patients treated with cisplatin: Relationship between peak ultrafilterable platinum plasma levels and nephrotoxicity
    • Reece PA, Stafford I, Russell J, et al: Creatinine clearance as a predictor of ultrafilterable platinum disposition in cancer patients treated with cisplatin: Relationship between peak ultrafilterable platinum plasma levels and nephrotoxicity. J Clin Oncol 5:304-309, 1987.
    • (1987) J Clin Oncol , vol.5 , pp. 304-309
    • Reece, P.A.1    Stafford, I.2    Russell, J.3
  • 31
    • 0024465181 scopus 로고
    • Randomized trial in advanced ovarian cancer comparing cisplatin and carboplatin
    • Mangioni C, Bolis S, Pecorelli S, et al: Randomized trial in advanced ovarian cancer comparing cisplatin and carboplatin. J Natl Cancer Inst 81:1464-1471, 1989.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1464-1471
    • Mangioni, C.1    Bolis, S.2    Pecorelli, S.3
  • 32
    • 0023682390 scopus 로고
    • Comparative toxicity of cisplatin, carboplatin (CBDCA) and iproplatin (CHIP) in combination with cyclophosphamide in patients with advanced epithelial ovarian cancer
    • Anderson H, Wagstaff J, Crowther D, et al: Comparative toxicity of cisplatin, carboplatin (CBDCA) and iproplatin (CHIP) in combination with cyclophosphamide in patients with advanced epithelial ovarian cancer. Eur J Cancer Clin Oncol 4:1471-1479, 1988.
    • (1988) Eur J Cancer Clin Oncol , vol.4 , pp. 1471-1479
    • Anderson, H.1    Wagstaff, J.2    Crowther, D.3
  • 33
    • 0023579941 scopus 로고
    • Randomized trial comparing two combination chemotherapy regimens (CHAP-5 v CP) in advanced ovarian carcinoma
    • Neijt JP, ten Bokkel Huinink WW, Van Der Burg MEL, et al: Randomized trial comparing two combination chemotherapy regimens (CHAP-5 v CP) in advanced ovarian carcinoma. J Clin Oncol 5:1157-1168, 1987.
    • (1987) J Clin Oncol , vol.5 , pp. 1157-1168
    • Neijt, J.P.1    Ten Bokkel Huinink, W.W.2    Van Der Burg, M.E.L.3
  • 34
    • 0022993630 scopus 로고
    • Cumulative renal tubular damage associated with cisplatin nephrotoxicity
    • Goren MP, Wright RK, Horowitz ME: Cumulative renal tubular damage associated with cisplatin nephrotoxicity. Cancer Chemother Pharmacol 18:69-73, 1986.
    • (1986) Cancer Chemother Pharmacol , vol.18 , pp. 69-73
    • Goren, M.P.1    Wright, R.K.2    Horowitz, M.E.3
  • 35
    • 0023028271 scopus 로고
    • The long-term effect of cisplatin on renal function
    • Fjeldborg P, Sorensen J, Helkjaer PE: The long-term effect of cisplatin on renal function. Cancer 58:2214-2217, 1986.
    • (1986) Cancer , vol.58 , pp. 2214-2217
    • Fjeldborg, P.1    Sorensen, J.2    Helkjaer, P.E.3
  • 36
    • 0018100922 scopus 로고
    • Long-term effect of cis-diamminedichloride platinum (CDDP) on renal function and structure in man
    • Dentino M, Luft FC, Yum MN, et al: Long-term effect of cis-diamminedichloride platinum (CDDP) on renal function and structure in man. Cancer 41:1274-1281, 1978.
    • (1978) Cancer , vol.41 , pp. 1274-1281
    • Dentino, M.1    Luft, F.C.2    Yum, M.N.3
  • 37
    • 0022496829 scopus 로고
    • Acute and long-term nephrotoxicity of cis-platinum in man
    • Groth S, Nielson H, Srenson JB, et al: Acute and long-term nephrotoxicity of cis-platinum in man. Cancer Chemother Pharmacol 17:191-196, 1986.
    • (1986) Cancer Chemother Pharmacol , vol.17 , pp. 191-196
    • Groth, S.1    Nielson, H.2    Srenson, J.B.3
  • 38
    • 0022911324 scopus 로고
    • Safe, rapid administration of cisplatin in the outpatient clinic
    • Brock J, Alberts DS: Safe, rapid administration of cisplatin in the outpatient clinic. Cancer Treat Rep 70:1409-1414, 1986.
    • (1986) Cancer Treat Rep , vol.70 , pp. 1409-1414
    • Brock, J.1    Alberts, D.S.2
  • 39
    • 0021140708 scopus 로고
    • Lack of age-dependent cisplatin nephrotoxicity
    • Hrushesky WJM, Shimp W, Kennedy BJ: Lack of age-dependent cisplatin nephrotoxicity. Am J Med 76:579-584, 1984.
    • (1984) Am J Med , vol.76 , pp. 579-584
    • Hrushesky, W.J.M.1    Shimp, W.2    Kennedy, B.J.3
  • 40
    • 0022409665 scopus 로고
    • Hypomagnesemia, renal dysfunction, and Raynaud's phenomenon in patients treated with cisplatin, vinblastine, and bleomycin
    • Vogelzang NJ, Torkelson JL, Kennedy BJ: Hypomagnesemia, renal dysfunction, and Raynaud's phenomenon in patients treated with cisplatin, vinblastine, and bleomycin. Cancer 56:2765-2770, 1985.
    • (1985) Cancer , vol.56 , pp. 2765-2770
    • Vogelzang, N.J.1    Torkelson, J.L.2    Kennedy, B.J.3
  • 41
    • 0023948344 scopus 로고
    • Cisplatin neuropathy: Risk factors, prognosis, and protection by WR-2721
    • Mollman JE, Glover DJ, Hogan WM, et al: Cisplatin neuropathy: Risk factors, prognosis, and protection by WR-2721. Cancer 61:2192-2195, 1988.
    • (1988) Cancer , vol.61 , pp. 2192-2195
    • Mollman, J.E.1    Glover, D.J.2    Hogan, W.M.3
  • 42
    • 0028364704 scopus 로고
    • Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
    • Shpall EJ, Stemmer SM, Hami L, et al: Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. Blood 83:3132-3137, 1994.
    • (1994) Blood , vol.83 , pp. 3132-3137
    • Shpall, E.J.1    Stemmer, S.M.2    Hami, L.3
  • 43
    • 0346806835 scopus 로고
    • Amifostine (WR-2721) shortens the engraftment time of 4-hydroperoxycyclophosphamide (4-HC) purged bone marrow in lymphoma patients receiving high-dose chemotherapy (HDC) with autologous bone marrow support (ABMS)
    • Stemmer SM, Shpall EJ, Jones RB, et al: Amifostine (WR-2721) shortens the engraftment time of 4-hydroperoxycyclophosphamide (4-HC) purged bone marrow in lymphoma patients receiving high-dose chemotherapy (HDC) with autologous bone marrow support (ABMS). Blood 80(10; suppl 1):70a, 1992.
    • (1992) Blood , vol.80 , Issue.10 SUPPL. 1
    • Stemmer, S.M.1    Shpall, E.J.2    Jones, R.B.3
  • 44
    • 0029162994 scopus 로고
    • Amifostine improves the antileukemic therapeutic index of mafosfamide: Implications for bone marrow purging
    • Douay L, Hu C, Giarratana MC, et al: Amifostine improves the antileukemic therapeutic index of mafosfamide: Implications for bone marrow purging. Blood 86(7):2849-2855, 1995.
    • (1995) Blood , vol.86 , Issue.7 , pp. 2849-2855
    • Douay, L.1    Hu, C.2    Giarratana, M.C.3
  • 45
    • 0020413641 scopus 로고
    • Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721
    • Valeriote F, Tolen S: Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721. Cancer Res 42:4330-4331, 1982.
    • (1982) Cancer Res , vol.42 , pp. 4330-4331
    • Valeriote, F.1    Tolen, S.2
  • 46
    • 0028323126 scopus 로고
    • Effects of the modulating agent WR-2721 on myelotoxicity and antitumour activity in carboplatin-treated mice
    • Treskes M, Boven E, Loosdrecht AA, et al: Effects of the modulating agent WR-2721 on myelotoxicity and antitumour activity in carboplatin-treated mice. Eur J Cancer 30:183-187, 1994.
    • (1994) Eur J Cancer , vol.30 , pp. 183-187
    • Treskes, M.1    Boven, E.2    Loosdrecht, A.A.3
  • 47
    • 0031427376 scopus 로고    scopus 로고
    • Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained
    • Taylor CW, Wang LM, List AF, et al: Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained. Eur J Cancer 33:1693-1698, 1997.
    • (1997) Eur J Cancer , vol.33 , pp. 1693-1698
    • Taylor, C.W.1    Wang, L.M.2    List, A.F.3
  • 48
    • 0006963475 scopus 로고
    • WR-2721 chemoprotection of doxorubicin toxicity in mice
    • Green D, Wright A, Schein PS, et al: WR-2721 chemoprotection of doxorubicin toxicity in mice (abstract). Proc Am Assoc Cancer Res 33:490, 1992.
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 490
    • Green, D.1    Wright, A.2    Schein, P.S.3
  • 49
    • 0028006635 scopus 로고
    • Granulocyte colony-stimulating factor and amifostine (Ethyol) synergize to enhance hemopoietic reconstitution and increase survival in irradiated animals
    • Patchen ML, MacVittie TJ: Granulocyte colony-stimulating factor and amifostine (Ethyol) synergize to enhance hemopoietic reconstitution and increase survival in irradiated animals. Semin Oncol 21:26-32, 1994.
    • (1994) Semin Oncol , vol.21 , pp. 26-32
    • Patchen, M.L.1    MacVittie, T.J.2
  • 50
    • 0343690945 scopus 로고
    • Enhanced recovery from supralethal radiation exposure using combined modality WR-2721 plus recombinant human (rh) G-CSF
    • MacVittie TJ, Brandenburg R, Farese AM, et al: Enhanced recovery from supralethal radiation exposure using combined modality WR-2721 plus recombinant human (rh) G-CSF (abstract). Proc Am Assoc Cancer Res 33:505, 1992.
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 505
    • MacVittie, T.J.1    Brandenburg, R.2    Farese, A.M.3
  • 51
    • 24244467995 scopus 로고    scopus 로고
    • A phase III randomised study of carboplatin and amifostine versus carboplatin and G-CSF in patients with inoperable non-small-cell lung cancer (NSCLC)
    • Mercer V, Anderson H, Habboubi N, et al: A phase III randomised study of carboplatin and amifostine versus carboplatin and G-CSF in patients with inoperable non-small-cell lung cancer (NSCLC) (abstract). Proc Am Soc Clin Oncol 16:474a, 1997.
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Mercer, V.1    Anderson, H.2    Habboubi, N.3
  • 52
    • 0029906872 scopus 로고    scopus 로고
    • Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro
    • Dorr RT, Lagel K, McLean S: Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro. Eur J Cancer 32A(suppl4):S21-25, 1996.
    • (1996) Eur J Cancer , vol.32 A , Issue.4 SUPPL.
    • Dorr, R.T.1    Lagel, K.2    McLean, S.3
  • 53
    • 0041435057 scopus 로고    scopus 로고
    • Amifostine (AMF) protects against doxorubicin (D) toxicity with preservation of therapeutic activity in advanced breast cancer (ABC) patients
    • De Lena M, Catino A, Calabrese P, et al: Amifostine (AMF) protects against doxorubicin (D) toxicity with preservation of therapeutic activity in advanced breast cancer (ABC) patients (abstract). Proc Am Soc Clin Oncol 17:137a 1998.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • De Lena, M.1    Catino, A.2    Calabrese, P.3
  • 54
    • 0032211299 scopus 로고    scopus 로고
    • Modulation of bleomycin-induced pulmonary toxicity in the hamster by the antioxidant, amifostine
    • in press
    • Nici L, Kuhn C, Calabresi P: Modulation of bleomycin-induced pulmonary toxicity in the hamster by the antioxidant, amifostine. Cancer, 1998 (in press).
    • (1998) Cancer
    • Nici, L.1    Kuhn, C.2    Calabresi, P.3
  • 55
    • 0019304979 scopus 로고
    • The role of WR-2721 in radiotherapy and/or chemotherapy
    • Yuhas JM, Spellman JM, Culo F: The role of WR-2721 in radiotherapy and/or chemotherapy. Cancer Clin Trials 3:211-216, 1980.
    • (1980) Cancer Clin Trials , vol.3 , pp. 211-216
    • Yuhas, J.M.1    Spellman, J.M.2    Culo, F.3
  • 56
    • 0014468075 scopus 로고
    • Differential chemoprotection of normal and malignant tissues
    • Yuhas JM, Storer JB: Differential chemoprotection of normal and malignant tissues. J Natl Cancer Inst 42:331-335, 1969.
    • (1969) J Natl Cancer Inst , vol.42 , pp. 331-335
    • Yuhas, J.M.1    Storer, J.B.2
  • 57
    • 0019424730 scopus 로고
    • Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721
    • Wasserman TH, Phillips TL, Ross G, et al: Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721. Cancer Clin Trials 4:3-6, 1981.
    • (1981) Cancer Clin Trials , vol.4 , pp. 3-6
    • Wasserman, T.H.1    Phillips, T.L.2    Ross, G.3
  • 58
    • 0019988331 scopus 로고
    • Protective effects of WR-2721 against radiation-induced injury of murine gut, testis, lung, and lung tumor nodules
    • Milas L, Hunter N, Reid BO: Protective effects of WR-2721 against radiation-induced injury of murine gut, testis, lung, and lung tumor nodules. Int J Radiat Oncol Biol Phys 8:535-538, 1982.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 535-538
    • Milas, L.1    Hunter, N.2    Reid, B.O.3
  • 59
    • 0026596470 scopus 로고
    • Use of radiation with or without WR-2721 in advanced rectal cancer
    • Liu T, Liu Y, He S, et al: Use of radiation with or without WR-2721 in advanced rectal cancer. Cancer 69:2820-2825, 1992.
    • (1992) Cancer , vol.69 , pp. 2820-2825
    • Liu, T.1    Liu, Y.2    He, S.3
  • 60
    • 0021112025 scopus 로고
    • Studies on the radioprotective effects of YM-08310 (WR-2721): Part 1. Radioprotective effects of YM-08310 on normal and malignant tissues in mice
    • Tanaka Y, Akagi K, Hasegawa T, et al: Studies on the radioprotective effects of YM-08310 (WR-2721): Part 1. Radioprotective effects of YM-08310 on normal and malignant tissues in mice. Nippon Igaku Hoshasen Gakkai Zasshi 43:700-709, 1983.
    • (1983) Nippon Igaku Hoshasen Gakkai Zasshi , vol.43 , pp. 700-709
    • Tanaka, Y.1    Akagi, K.2    Hasegawa, T.3
  • 61
    • 0031840023 scopus 로고    scopus 로고
    • Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer
    • Büntzel J, Kuttner K, Frohlich D, et al: Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer. Ann Oncol 9:505-509, 1998.
    • (1998) Ann Oncol , vol.9 , pp. 505-509
    • Büntzel, J.1    Kuttner, K.2    Frohlich, D.3
  • 62
    • 0000660112 scopus 로고    scopus 로고
    • Randomized phase III trial of radiation ± amifostine in patients with head and neck cancer
    • Brizel D, Sauer R, Wannenmacher M, et al: Randomized phase III trial of radiation ± amifostine in patients with head and neck cancer (abstract). Proc Am Soc Clin Oncol 17:386a, 1998.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Brizel, D.1    Sauer, R.2    Wannenmacher, M.3
  • 63
    • 0000994958 scopus 로고
    • Amifostine preserves the salivary gland function during irradiation of the head and neck
    • McDonald S, Meyerowitz C, Smudzin T, et al: Amifostine preserves the salivary gland function during irradiation of the head and neck. Eur J Cancer 31a(suppl 5):415, 1995.
    • (1995) Eur J Cancer , vol.31 A , Issue.5 SUPPL. , pp. 415
    • McDonald, S.1    Meyerowitz, C.2    Smudzin, T.3
  • 64
    • 0024364159 scopus 로고
    • Purging of small-cell lung cancer cells from human bone marrow using ethiofos (WR-2721) and light-activated merocyanine 540 phototreatment
    • Meagher RC, Rothman SA, Paul P, et al: Purging of small-cell lung cancer cells from human bone marrow using ethiofos (WR-2721) and light-activated merocyanine 540 phototreatment. Cancer Res 49:3637-3641, 1989.
    • (1989) Cancer Res , vol.49 , pp. 3637-3641
    • Meagher, R.C.1    Rothman, S.A.2    Paul, P.3
  • 65
    • 0029743651 scopus 로고    scopus 로고
    • Amifostine protects primitive hematopoietic progenitors against chemotherapy cytotoxicity
    • List AF, Heaton R, Glinsmann-Gibson B, et al: Amifostine protects primitive hematopoietic progenitors against chemotherapy cytotoxicity. Semin Oncol 23(4; suppl 8):58-63, 1996.
    • (1996) Semin Oncol , vol.23 , Issue.4 SUPPL. 8 , pp. 58-63
    • List, A.F.1    Heaton, R.2    Glinsmann-Gibson, B.3
  • 66
    • 0030735082 scopus 로고    scopus 로고
    • Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome
    • List AF, Brasfield F, Heaton R, et al: Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome. Blood 90:3364-3369, 1997.
    • (1997) Blood , vol.90 , pp. 3364-3369
    • List, A.F.1    Brasfield, F.2    Heaton, R.3
  • 67
    • 24844458575 scopus 로고    scopus 로고
    • Combination of pentoxifylline (PTX), ciprofloxacin (Cipro), dexamethasone (PCD) with amifostine improves ineffective hematopoiesis in 70% of patients with myelodysplastic syndromes (MDS)
    • Raza A, Andric T, Oawi LL, et al: Combination of pentoxifylline (PTX), ciprofloxacin (Cipro), dexamethasone (PCD) with amifostine improves ineffective hematopoiesis in 70% of patients with myelodysplastic syndromes (MDS) (abstract). Blood 90:84a, 1997.
    • (1997) Blood , vol.90
    • Raza, A.1    Andric, T.2    Oawi, L.L.3
  • 68
    • 0343940617 scopus 로고    scopus 로고
    • Preliminary results of a phase II study of amifostine for patients with myelodysplastic syndrome
    • deCastro CM, Gockerman JP, Moor JO, et al: Preliminary results of a phase II study of amifostine for patients with myelodysplastic syndrome (abstract). Blood 90:286b, 1997.
    • (1997) Blood , vol.90
    • DeCastro, C.M.1    Gockerman, J.P.2    Moor, J.O.3
  • 69
    • 0022551072 scopus 로고
    • Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol
    • Nagy B, Dale PJ, Grdina DJ: Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol. Cancer Res 46:1132-1135, 1986.
    • (1986) Cancer Res , vol.46 , pp. 1132-1135
    • Nagy, B.1    Dale, P.J.2    Grdina, D.J.3
  • 70
    • 0022538195 scopus 로고
    • Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells
    • Nagy B, Grdina DJ: Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells. Int J Radiat Oncol Biol Phys 12:1475-1478, 1986.
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1475-1478
    • Nagy, B.1    Grdina, D.J.2
  • 71
    • 0023196369 scopus 로고
    • The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells
    • Sigdestad CP, Treacy SH, Knapp LA, et al: The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells. Br J Cancer 55:477-482, 1987.
    • (1987) Br J Cancer , vol.55 , pp. 477-482
    • Sigdestad, C.P.1    Treacy, S.H.2    Knapp, L.A.3
  • 72
    • 0346176204 scopus 로고
    • Spermine and the disulfide WR-33278 protect against radiation-induced cell killing and mutagenesis
    • Shigematsu N, Dale P, Schwartz J, et al: Spermine and the disulfide WR-33278 protect against radiation-induced cell killing and mutagenesis (abstract). Radiat Res 167:32-33, 1993.
    • (1993) Radiat Res , vol.167 , pp. 32-33
    • Shigematsu, N.1    Dale, P.2    Schwartz, J.3
  • 73
    • 0028953642 scopus 로고
    • Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anticytotoxic and antimulagenic mechanisms of action
    • Grdina DJ, Shigematsu N, Dale P, et al: Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anticytotoxic and antimulagenic mechanisms of action. J Carcinogenesis 16(4):767-774, 1995.
    • (1995) J Carcinogenesis , vol.16 , Issue.4 , pp. 767-774
    • Grdina, D.J.1    Shigematsu, N.2    Dale, P.3
  • 74
    • 0347437415 scopus 로고
    • Amifostine protects against cyclophosphamide and cisplatin-induced mutagenesis without affecting therapeutic effectiveness
    • Kataoka Y, Perrin J, Hunter N, et al: Amifostine protects against cyclophosphamide and cisplatin-induced mutagenesis without affecting therapeutic effectiveness. Eur J Cancer 31a(suppl 5):110, 1995.
    • (1995) Eur J Cancer , vol.31 A , Issue.5 SUPPL. , pp. 110
    • Kataoka, Y.1    Perrin, J.2    Hunter, N.3
  • 75
    • 0029762414 scopus 로고    scopus 로고
    • Antimutagenic effects of amifostine: Clinical implications
    • Kataoka Y, Perrin J, Hunter N, et al: Antimutagenic effects of amifostine: Clinical implications. Semin Oncol 23(4; suppl 8):53-57, 1996.
    • (1996) Semin Oncol , vol.23 , Issue.4 SUPPL. 8 , pp. 53-57
    • Kataoka, Y.1    Perrin, J.2    Hunter, N.3
  • 76
    • 0021718290 scopus 로고
    • Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
    • Milas L, Hunter N, Stephens LC, et al: Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid. Cancer Res 44:5567-5569, 1984.
    • (1984) Cancer Res , vol.44 , pp. 5567-5569
    • Milas, L.1    Hunter, N.2    Stephens, L.C.3
  • 77
    • 0029877511 scopus 로고    scopus 로고
    • Breast cancer and other second neoplasms after childhood Hodgkin's disease
    • Bhatia S, Robison LL, Oberlin O, et al: Breast cancer and other second neoplasms after childhood Hodgkin's disease. N Engl J Med 334:745-751, 1996.
    • (1996) N Engl J Med , vol.334 , pp. 745-751
    • Bhatia, S.1    Robison, L.L.2    Oberlin, O.3
  • 78
    • 0001968118 scopus 로고    scopus 로고
    • Amifostine and dose intense paclitaxel in patients with advanced malignancies
    • DiPaola RS, Rodriguez R, Goodin S, et al: Amifostine and dose intense paclitaxel in patients with advanced malignancies. Cancer Ther 1:11-17, 1998.
    • (1998) Cancer Ther , vol.1 , pp. 11-17
    • DiPaola, R.S.1    Rodriguez, R.2    Goodin, S.3
  • 79
    • 0029609416 scopus 로고
    • Carboplatin combined with amifostine, a bone marrow protectant, in the treatment of non-small-cell lung cancer: A randomised phase II study
    • Betticher DC, Anderson H, Ranson M, et al: Carboplatin combined with amifostine, a bone marrow protectant, in the treatment of non-small-cell lung cancer: A randomised phase II study. Br J Cancer 72(6):1551-1555, 1995.
    • (1995) Br J Cancer , vol.72 , Issue.6 , pp. 1551-1555
    • Betticher, D.C.1    Anderson, H.2    Ranson, M.3
  • 80
    • 0030826795 scopus 로고    scopus 로고
    • Randomized trial of carboplatin plus amifostine vs carboplatin alone in patients with advanced solid tumors
    • Budd GT, Ganapathi R, Adelstein DJ, et al: Randomized trial of carboplatin plus amifostine vs carboplatin alone in patients with advanced solid tumors. Cancer 80:1134-1140, 1997.
    • (1997) Cancer , vol.80 , pp. 1134-1140
    • Budd, G.T.1    Ganapathi, R.2    Adelstein, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.