Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins

International Journal of Cancer

Volumn 72, Issue 3, 1997, Pages 498-504

  Aprikian, Armen G ^a   Tremblay, Lise ^a   Han, Kehan ^a   Chevalier, Simone ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BOMBESIN; BOMBESIN DERIVATIVE; CYTOCHALASIN D; FOCAL ADHESION KINASE; INTEGRIN; PAXILLIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROTEIN KINASE C; TYROSINE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CELL MOTILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CARCINOMA; TUMOR CELL LINE;

BOMBESIN; CELL ADHESION MOLECULES; CELL MOVEMENT; CYTOSKELETAL PROTEINS; EXTRACELLULAR MATRIX PROTEINS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; IMMUNOSORBENT TECHNIQUES; INTEGRINS; MALE; NEOPLASM INVASIVENESS; PAXILLIN; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROSTATIC NEOPLASMS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0030787791     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970729)72:3<498::AID-IJC19>3.0.CO;2-8     Document Type: Article

References (29)

1. AKIYAMA, T., ISHIDA, J., NAKAGAWA, S., OGAWARA, H., WATANABE, S., ITOH, N., SMIBUYA, M. and FUKAMI, Y., Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. biol. Chem., 262, 5592-5595 (1987).
2. APRIKIAN, A.G., CORDON-CARDO, C., FAIR, W.R. and REUTER, V.E., Characterization of neuroendocrine differentiation in human benign prostate and prostatic adenocarcinoma. Cancer, 71, 3952-3965 (1993).
3. APRIKIAN, A.G., CORDON-CARDO, C., FAIR, W.R., ZHANG, Z.F., BAZINET, M., HAMDY, S.M. and RHUTER, V.E., Neuroendocrine differentiation in metastatic prostatic adenocarcinoma. J. Urol., 151, 914-919 (1994).
4. APRIKIAN, A.G., HAN, K., CHEVALIER, S., BAZINET, M. and VIALLET, J., Bombesin specifically induces intracellular calcium mobilisation via gastrin-releasing peptide receptors in human prostate cancer cells. J. mol. Endocrinol., 16, 297-306 (1996).
5. BOLOGNA, M., FESTUCCIA, C., MUZI, P., BIORDI, L. and CIOME, N., Bombesin stimulates growth of human prostatic cancer cells in vitro. Cancer, 63, 1714-1720 (1989).
6. CLARK, E.A. and BRUGGE, J.S., Integrins and signal transduction pathways: the road taken. Science, 268, 233-239 (1995).
7. COHEN, R.J., GLEZERSON, G. and HAFFEGE, A., Neuro-endocrine cells - a new parameter in prostate cancer. Brit. J. Urol., 68, 258-262 (1991).
8. COOPER, J.A., Effects of cytochalasin and phalloidin on actin. J. Cell Biol., 105, 1473-1478 (1987).
9. DEDHAR, S., Integrin mediated signal transduction in oncogenesis: an overview. Cancer Metastasis Reviews, 14, 165-172 (1995).
10. FAK) in prostate carcinoma. J. surg. Res., 63, 359-363 (1996).
11. GIANCOTTI, F.G. and MAINIERO, F., Integrin-mediated adhesion and signaling in tumorigenesis. Biochem. biophys. Acta, 1198, 47-64 (1994).
12. HAN, K., VIALLET, J., CHEVALIER, S., ZHENG, W., BAZINET, M. and APRIKIAN, A.G., Characterisation of intracellular calcium mobilisation by bombesin-related neuropeptides in PC-3 human prostate cancer cells. Prostate, 31, 53-60 (1997).
13. HEIDERMANN, S.R., A new twist on integrins and the cytoskeleton. Science, 260, 1080-1081 (1993).
14. HERGET, T. and ROZENGURT, E., Bombesin, endothelin and platelet-derived growth factor induce rapid translocation of the myristoylated alanine-rich C-kinase substrate in Swiss 3T3 cells. Enrop. J. Biochem., 225, 539-548 (1994).
15. HOOSEIN, N.M., LOGOTHETIS, C. and CHUNG, L.W.K., Differential effects of peptide hormones bombesin, vasoactive intestinal polypeptide and somatostatin analog RC-160 on the invasive capacity of human prostatic carcinoma cells. J. Urol., 149, 1209-1213 (1993).
16. ILIC, D., FURUTA, Y., KANAZAWA, S., TAKEDA, N., SOBUE, K., NAKATSU, JL, NOMURA, S., FUJIMOTO, J., OKADA, M., YAMAMOTO, T. and ALZAMA, S., Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (Lond.), 377, 539-544 (1995).
17. KADMON, D., THOMPSON, T.C., LYNCH, G.R. and SCARDINO, P.T., Elevated plasma chromogranin-A concentration in prostate carcinoma. J. Urol., 146, 358-361 (1991).
18. PASSANITI, A., ISAACS, J.T., HANEY, J.A., ADLER, S.W., CUJDIK, T.J., LONG, P.V. and KLEINMAN, H.K., Stimulation of human prostatic carcinoma growth in uthymic mice and control of migration in culture by extracellular matrix. Int. J. Cancer, 51, 318-324 (1992).
19. PETERSON, G., Evaluation of the biochemical targets of genistein in tumor cells. J. Nutrition, 125 (Suppl. 3), 784S-789S (1995).
20. SASTRY, S.K. and HORWITZ, A.F., Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intrucellular initiated transmembrane signaling. Curr. Opin. Cell Biol., 5, 819-831 (1993).
21. FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc. nat. Acad. Sci. (Wash.), 89, 5192-5196 (1992).
22. SCHALLER, M.D., OTEY, C.A., HILDEBRAND, J.D. and PARSONS, J.T., Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J. Cell Biol., 130, 1181-1187 (1995).
23. SCHALLER, M.D. and PARSONS, J.T., Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol., 6, 705-710 (1994).
24. SEFTOR, R.E., SEFTOR, E.A., STETLER-STEVENSON, W.G. and HENDRIX, M.J., The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion. Cancer Res., 53, 3411-3415 (1993).
25. 2+ mobilization, and the actin cytoskeleton. J. biol. Chem., 268, 14261-14268 (1993).
26. TAPLEY, P., HORWITZ, A.F., BUCK, C., DUGGAN, K. and ROHRSCHNEIDER, L., Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts. Oncogene, 4, 325-333 (1989).
27. CSK in human metastatic prostate carcinoma. Int. J. Cancer, 68, 164-171 (1996).
28. WITKOWSKI, C.M., RABINOVITZ, I., NAGLE, R.B., AFFINITO, K.-S.D. and CRESS, A.E., Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines. J. Cancer Res. clin. Oncol., 119, 637-644 (1993).
29. ZACHARY, I., SINNETT-SMITH, J., TURNER, C.E. and ROZENGURT, E., Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of focal adhesion-associated protein paxillin in Swiss 3T3 cells. J. biol. Chem., 268, 22060-22065 (1993).