Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma model

Medical and Pediatric Oncology

Volumn 35, Issue 6, 2000, Pages 585-589

  Norris, M D ^a   Burkhart, C A ^a   Marshall, G M ^a   Weiss, W A ^b   Haber, M ^a  

^a CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN; ONCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CANCER INCIDENCE; CONFERENCE PAPER; CONTROLLED STUDY; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MOUSE; MULTIDRUG RESISTANCE; NEUROBLASTOMA; NONHUMAN; ONCOGENE C MYB; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; TRANSGENIC MOUSE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DISEASE MODELS, ANIMAL; GENE DOSAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HUMANS; MICE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NEUROBLASTOMA;

EID: 0033646540     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-911X(20001201)35:6<585::AID-MPO20>3.0.CO;2-P     Document Type: Conference Paper

References (11)

1. Neuroblastoma
2. Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma
3. Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma
4. Altered expression of the MYCN oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells
5. Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma
6. Targeted expression of MYCN causes neuroblastoma in transgenic mice
7. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
8. MYCN Expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with unamplified MYCN
9. Prognostic significance of MYCN oncogene expression in childhood neuroblastoma
10. myc Gene amplification and expression in primary human neuroblastoma
11. N-myc oncogene RNA expression in neuroblastoma