A novel rat model of chronic fibrosing cholangitis induced by local administration of a hapten reagent into the dilated bile duct is associated with increased TNF-α production and autoantibodies

Journal of Hepatology

Volumn 33, Issue 6, 2000, Pages 862-872

  Orth, Thomas ^a,c   Neurath, Markus ^a   Schirmacher, Peter ^b   Galle, Peter R ^a   Mayet, Werner Johannes ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c Thomas Orth   (Germany)

Author keywords

Anti neutrophil cytoplasmic antibodies (ANCA); Autoantibody; IL 10; Liver; Primary sclerosing cholangitis; Rat; TNF alpha

Indexed keywords

ACTIN; ALKALINE PHOSPHATASE; AUTOANTIBODY; CATALASE; CD3 ANTIGEN; CELL ANTIBODY; GAMMA INTERFERON; HAPTEN; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT MALFORMATION; CELL DESTRUCTION; CHOLANGIOGRAPHY; CHOLANGITIS; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STENOSIS; T LYMPHOCYTE;

EID: 0033645662     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(00)80116-6     Document Type: Article

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