Keloids in rural black South Africans. Part 3: A lipid model for the prevention and treatment of keloid formations

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 63, Issue 5, 2000, Pages 255-262

  Louw, L ^a  

^a UNIVERSITY OF THE FREE STATE   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CHOLESTEROL ESTER; COLLAGEN; CYTOKINE; DIHOMO GAMMA LINOLENIC ACID; FATTY ACID; FREE RADICAL; GAMMA LINOLENIC ACID; GROWTH FACTOR; ICOSANOID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LIPID; OLEIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; OXYGEN; PHOSPHOLIPASE A2; PHOSPHOLIPID; PROSTAGLANDIN E2; PROTEIN KINASE C; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL;

ANGIOGENESIS; APOPTOSIS; ARTICLE; BLOOD VESSEL OCCLUSION; CELL PROLIFERATION; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; FAT INTAKE; FIBROBLAST; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOXEMIA; IMMUNOMODULATION; KELOID; NEGRO; NUTRITIONAL STATUS; PATHOGENESIS; PRIORITY JOURNAL; RURAL POPULATION; SIGNAL TRANSDUCTION; SOUTH AFRICA;

EID: 0033636658     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.2000.0209     Document Type: Article

References (46)

1. Hypertrophic scars and keloids: A recurrent problem revisited
2. Fatty acids and cell signal transduction
3. Interferons, phospholipid metabolism, immune response and cancer
4. Apoptosis and proliferation: Possible implications in the aetiology of keloids
5. The microvessels in hypertrophic scars, keloids and related lesions: A review
6. Ultrastructural characteristics of keloid fibroblasts
7. Contributions of electron microscopy to the study of the hypertrophic scar and related lesions
8. Apoptosis: A current molecular analysis
9. Inhibition of human fibroblast growth in vitro by snake oil
10. Background to essential fatty acids and their prostanoid derivates
11. Medical uses of essential fatty acids
12. Linoleic acid in hypertrophic scars
13. Nutritional and medical importance of gamma-linolenic acid
14. A simple method for the isolation and purification of total lipids from animal tissues
15. Rapid isolation of neuroblastoma plasma membranes on Percoil gradients. Characterization and lipid composition
16. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol
17. One-step rapid extractive methylation of plasma nonesterified fatty acids for gas chromatographic analysis
18. Confidence intervals rather than p-values: Estimation rather than hypothesis testing
19. Keloids in rural black South Africans. Part 2: Dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients
20. Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets
21. Differential activation of PKC is associated with arachidonate release in Madin-Darbin canine kidney cells
22. Activation of protein kinase C by oleic acid
23. Biological significance of arachidonic acid
24. Essential fatty acids and inflammation
25. Interactions between essential fatty acids, eicosanoids, cytokines, growth factors and free radicals
26. Immunologic associations of keloids
27. Fibronectin is overproduced by keloid fibroblasts during abnormal wound healing
28. The phospholipid analogue hexadecylphosphocholine (HePC) inhibits proliferation of keloid fibroblasts in vitro and modulates their fibronectin and integrin synthesis
29. Quantative measurement of sn-1,2-diacylglycerol present in platelets, hepatocytes and ras- and sis-transformed normal rat kidney cells
30. Selective phosphorylation of human DNA methyltransferase by protein kinase C
31. Altered growth regulation and enhanced tumourigenecity of NIH 373 fibroblasts transfected with protein kinase c-1 cDHA
32. Effects of various growth factors and histamine on cultured keloid fibroblasts
33. Acidic and basic fibroblast growth factors down-regulate collagen gene expression in keloid fibroblasts
34. Modulation of collagen synthesis by transforming growth factor beta in keloid and hypertrophic scar fibroblasts
35. The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis
36. Regulation of collagen gene expression in keloids and hypertrophic scars
37. Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts
38. Suppressive effects of tranilast on the expression of inducible cyclo-oxygenase in interleukin-1 beta-stimulated fibroblasts
39. Proliferating activity of dermal fibroblasts in keloids and hypertrophic scars
40. Serum-free keloid fibroblast cell culture: An in vitro model for the study of aberrant wound healing
41. Is the excess linoleic acid syndrome confined to Japan?
42. Propiomelanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: Modulation by cytokines
43. Coordinate induction of collagen type 1 and biglycan expression in keloids
44. Tamoxifen down-regulates TGF-b production in keloid fibroblasts
45. Major suppression of pro-a 1(1) type 1 collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triamcinolone acetonide