Serum-free keloid fibroblast cell culture: An in vitro model for the study of aberrant wound healing

Plastic and Reconstructive Surgery

Volumn 99, Issue 4, 1997, Pages 1094-1098

  Koch, R James ^a   Goode, Richard L ^b   Simpson, George T ^b  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; KELOID; PRIORITY JOURNAL; SURGICAL APPROACH; SURGICAL TECHNIQUE; WOUND HEALING;

CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; FIBROBLASTS; HUMANS; KELOID; WOUND HEALING;

EID: 0030996247     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006534-199704000-00027     Document Type: Article

References (11)

1. Datubo-Brown, D. D. Keloids: A review of the literature. Br. J. Plast. Surg. 43: 70, 1990.
2. Cosman, B., and Wolff, M. Correlation of keloid recurrence with completeness of local excision. Plast. Reconstr. Surg. 50: 163, 1972.
3. Russell, S. B., Trupin, K. M., Rodriguez-Eaton, S., Russell, J. D., and Trupin, J. S. Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth. Proc. Natl. Acad. Sci. U. S. A. 85: 587, 1988.
4. Cruz, N. I., and Korchin, L. Inhibition of human keloid growth by isotretinoin and triamcinolone acetonide in vitro. Ann. Plast. Surg. 33: 401, 1994.
5. Gospodarowicz, D., Neufeld, G., and Schweiger, L. Fibroblast growth factor: Structural and biological properties. J. Cell Physiol. 5, (Suppl.): 15, 1987.
6. Burgess, W. H., and Maciag, T. The heparin-binding (fibroblast) growth factor family of proteins. Annu. Rev. Biochem. 58: 575, 1989.
7. Damon, D. H., Lobb, R. R., D'Amore, P. A., and Wagner, J. A. Heparin potentiates the action of acidic fibroblast growth factor by prolonging its biological half-life. J. Cell Physiol. 138: 221, 1989.
8. Sommer, A., and Rifkin, D.B. Interaction of heparin with human basic fibroblast growth factor: Protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan. J. Cell Physiol. 138: 215, 1989.
9. Tan, M. L., Rouda, S., Greenbaum, S. S., Moore, J. H., Fox, J. W., and Sollberg, S. Acidic and basic fibroblast growth factors down-regulate collagen gene expression in keloid fibroblasts. Am. J. Pathol. 142: 463, 1993.
10. Trupin, J. S., Russell, S. B., and Russell, J. D. Variation in prolyl hydroxylase activity of keloid-derived and normal human fibroblasts in response to hydrocortisone and ascorbic acid. Coll. Relat. Res. 3: 13, 1983.
11. Larrabee, W. F., Bolen, J. W., and Sutton, D. Myofibroblasts in head and neck surgery: An experimental and clinical study. Arch. Otolarynqol. Head Neck Surg. 114: 982, 1988.