Peptidomimetic antagonists of αvβ3 inhibit bone resorption by inhibiting osteoclast bone resorptive activity, not osteoclast adhesion to bone

Journal of Endocrinology

Volumn 165, Issue 3, 2000, Pages 587-598

  Carron, C P ^a   Meyer, D M ^a   Engleman, V W ^a   Rico, J G ^a   Ruminski, P G ^a   Ornberg, R L ^a   Westlin, W F ^a   Nickols, G A ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BETA [2 [[5 [[AMINOIMINOMETHYL]AMINO] 1 OXOPENTYL]AMINO] 1 OXOETHYL]AMINO 3 PYRIDINE PROPANOIC ACID; BETA [[1 OXO 2 [[[3 [[[(PHENYLMETHYL)AMINO]CARBONYL]AMINO]PHENYL]CARBONYL]AMINO]ETHYL]AMINO]PYRIDINE 3 PROPANOIC ACID; INTEGRIN RECEPTOR; OSTEOPONTIN; PEPTIDOMIMETIC ANTAGONIST; PROPIONIC ACID DERIVATIVE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VITRONECTIN; ANILINE DERIVATIVE; PEPTIDE; PYRIDINE DERIVATIVE; SC 56631; SC 65811; VITRONECTIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; ANIMAL; BONE; CULTURE TECHNIQUE; DOSE RESPONSE; DRUG ANTAGONISM; METABOLISM; MICROSCOPY; PATHOLOGY; PHYSIOLOGY; RABBIT;

ANILINE COMPOUNDS; ANIMALS; BONE AND BONES; BONE RESORPTION; CELL ADHESION; CELL CULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICROSCOPY, VIDEO; OSTEOCLASTS; PEPTIDES; PYRIDINES; RABBITS; RECEPTORS, VITRONECTIN;

EID: 0033625260     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1650587     Document Type: Article

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