Phe208 and Ile199 in human monoamine oxidase A and B do not determine substrate and inhibitor specificities as in rat

Journal of Neurochemistry

Volumn 75, Issue 3, 2000, Pages 1304-1309

  Geha, Rani Maurice ^a   Chen, Kevin ^a   Shih, Jean Chen ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Active site; Chimeric; Monoamine oxidase; Mutant

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); MONOAMINE OXIDASE INHIBITOR; CLORGYLINE; HYBRID PROTEIN; ISOENZYME; ISOLEUCINE; PHENYLALANINE; RECOMBINANT PROTEIN; SELEGILINE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; SACCHAROMYCES CEREVISIAE; XENOBIOTIC METABOLISM; ANIMAL; BINDING SITE; CHEMISTRY; ENZYMOLOGY; HUMAN; KINETICS; LIVER; METABOLISM; POINT MUTATION; SITE DIRECTED MUTAGENESIS;

ANIMALS; BINDING SITES; CLORGYLINE; HUMANS; ISOENZYMES; ISOLEUCINE; KINETICS; LIVER; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; POINT MUTATION; RATS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SELEGILINE; SUBSTRATE SPECIFICITY;

EID: 0033624499     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.751304.x     Document Type: Article

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