G protein βγ complexes in circumvallate taste cells involved in bitter transduction

Chemical Senses

Volumn 25, Issue 4, 2000, Pages 413-421

  Rössler, Patricia ^a   Boekhoff, Ingrid ^a   Tareilus, Erwin ^b   Beck, Stefan ^a   Breer, Heinz ^a   Freitag, Joachim ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DENATONIUM BENZOATE; GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHOLIPASE C; PROTEIN ANTIBODY; SCAVENGER; PRIMER DNA;

ANIMAL TISSUE; ARTICLE; CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECOND MESSENGER; SIGNAL TRANSDUCTION; TASTE BUD; TISSUE HOMOGENATE; ANIMAL; CYTOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; INOSITOL 1,4,5-TRISPHOSPHATE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TASTE BUDS;

EID: 0033624203     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Dual second-messenger pathways in olfactory transduction
2. A bitter substance induces a rise in intracellular calcium in a subpopulation of rat taste cells
3. 2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat
4. Olfactory desensitization requires membrane targeting of receptor kinase mediated by βγ-subunits of heterotrimeric G proteins
5. 2 by G protein βγ-subunits
6. G protein βγ subunits
7. Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases
8. Design of oligonucleotide probes for molecular cloning of β and γ subunits
9. The G-protein βγ complex
10. The many faces of G protein signaling
11. Putative mammalian taste receptors: A class of taste-specific GPCRs with distinct topographic selectivity
12. 3 responses to bitter denatonium
13. Localization of phosphatidylinositol signaling components in rat taste cells: Role in bitter taste transduction
14. Structural and mechanistic features of phospholipase C: Effectors of inositol phospholipid-mediated signal transduction
15. 2 isoform of phospholipase C
16. Mechanisms of taste transduction
17. The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
18. A cyclic-nucleotide suppressible conductance activated by transducin in taste cells
19. Differential expression of RNA and protein of the three pore-forming subunits of the amiloride-sensitive epithelia sodium channel in taste buds of the rat
20. 2 region that interacts with Gβγ
21. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
22. 2 hydrolysis and regulation of phospholipse C isozymes
23. 3 subunit, a third form of the G protein β-subunit polypetide
24. Taste reception
25. Chemoreception: Tasting the sweet and bitter
26. Gustducin is a taste-cell-specific G protein closely related to the transducins
27. Transduction for sweet taste of saccharin may involve both inositol 1,4,5-triphosphate and cAMP pathways in the fungiform taste buds in C57BL mice
28. Mass measurement of inositol 1,4,5-trisphospate using specific binding assay
29. 2
30. Activation of phospholipase C isozymes by G protein βγ subunits
31. Role of βγ subunits on G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors
32. 3 subunit
33. Identification of a phospholipase C β subtype in rat taste cells
34. Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells
35. 2 that interacts with G protein βγ subunits
36. A rapid method of collecting taste tissue from rats and mice
37. Generation of inositol phospates in bitter taste transduction
38. Rapid kinetics of second messenger production in bitter taste
39. Generation of cyclic AMP in taste buds of the rat circumvallate papilla in response to sucrose
40. A fifth member of the mammalian G-protein β-subunit family
41. Transduction of bitter and sweet taste by gustducin
42. 2 by the α and βγ subunits of trimeric GTP-binding protein
43. Role of two messenger in bitter taste transduction
44. Single-cell cDNA-PCR: Removal of contaminating genomic DNA from total RNA using immobilized DNase I