Gene transfer and cell transplant: An experimental approach to repair a 'broken heart'

Cardiovascular Research

Volumn 35, Issue 3, 1997, Pages 431-441

  Leor, Jonathan ^a   Prentice, Howard ^b,c   Sartorelli, Vittorio ^b,c   Quinones, Manuel J ^b,c   Patterson, Michael ^c   Kedes, Laurence K ^b,c   Kloner, Robert A ^c  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b GOOD SAMARITAN HOSPITAL   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cardiomyocyte; Gene therapy; Myocardial infarction; Rat

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CARDIOMYOPLASTY; CELL TRANSPLANTATION; CONTROLLED STUDY; GENE TRANSFER; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW;

CELL TRANSPLANTATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOD PROTEIN;

EID: 0030782262     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00159-4     Document Type: Review

References (41)

1. Eriksson H. Heart failure: a growing public health problem. J Intern Med. 237:1995;135-141.
2. Nabel E. Gene therapy for cardiovascular disease. Circulation. 91:1995;541-548.
3. Lafont A., Guerot C., Lemarchand P. Prospects of gene therapy in cardiovascular disease. Eur Heart J. 17:1996;1312-1317.
4. Kedes L., Kloner R.A., Starnes V.A. Can a few cells now mend a broken heart? J Clin Invest. 92:1993;1115-1116.
5. Cohn J.N. Critical review of heart failure: the role of left ventricular remodeling in the therapeutic response. Clin Cardiol. 8(Suppl IV):1995;IV4-IV12.
6. Katz A.M. Cell death in the failing heart: role of an unnatural growth response to overload. Clin Cardiol. 18(Suppl 4):1995;IV36-IV44.
7. Prentice H., Kloner R.A., Prigozy T.et al. Tissue restricted gene expression assayed by direct DNA injection into cardiac and skeletal muscle. J Mol Cell Cardiol. 26:1994;1393-1401.
8. Schneider M.D., French B.A. The advent of adenovirus: gene therapy for cardiovascular disease. Circulation. 88:1993;137-1942.
9. Quinones M.J., Leor J., Kloner R.A.et al. Avoidance of immune response prolongs expression of gene delivered to the adult rat myocardium by replication-defective adenovirus. Circulation. 94:1996;1394-1401.
10. Prentice H., Kloner R.A., Li Y., Newman L., Kedes L. Ischemic/reperfused myocardium can express recombinant protein following direct DNA or retroviral injection. J Mol Cell Cardiol. 28:1996;133-140.
11. Leor J., Quinones M.J., Patterson M., Kedes L., Kloner R.A. Adenovirus mediated gene transfer into infarcted myocardium: feasibility, timing, and location of expression. J Mol Cell Cardiol. 28:1996;2057-2067.
12. Weintraub H., Davis R., Tapscott S.et al. The MyoD gene family: nodal point during specification of the muscle cell lineage. Science. 251:1991;761-766.
13. Hooper T.L., Stephenson L.W. Cardiomyoplasty for end stage heart failure. Surg Annu. 1:1993;157-173.
14. Prentice H., Kloner R.A., Sartorelli V., Bellows S., Alder K., Kedes L. Transformation of cardiac fibroblasts into the ischemic heart. Circulation. 88(Suppl Part 2):1993;I-475. Abstract.
15. Tam S.K., Gu W., Nadal-Ginard B. Molecular cardiomyoplasty: potential cardiac gene therapy for chronic heart failure. J Thorac Cardiovasc Surg. 109:1995;918-923.
16. Murry C.E., Kay M.A., Bartosak T., Hauschka S.D., Schwartz S.M. Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with Myo D. J Clin Invest. 98:1966;2209-2217.
17. Soonpaa M.H., Koh G.Y., Klug M.G., Field L.J. Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science. 264:1994;98-101.
18. Koh G.Y., Soonpaa M.H., Klug M.G., Pride H.P., Cooper B.J., Zipes D.P., Field L.J. Stable fetal cardiomyocytes grafts in the hearts of dystrophic mice and dogs. J Clin Invest. 96:1995;2034-2042.
19. Leor J., Patterson M., Quinones M.J., Kedes L.H., Kloner R.A. Transplantation of fetal myocardial tissue into the infarcted myocardium of rat: a potential method for repair of infarcted myocardium. Circulation. 94(Suppl II):1996;II332-II336.
20. Scorsin M., Marotte F., Sabri A.et al. Can grafted cardiomyocytes colonize peri-infarct myocardial area? Circulation. 94(Suppl II):1996;II337-II340.
21. Scorsin M., Hagege A.A., Marotte F.et al. Does transplantation of cardiomyocytes improve function of infarcted myocardium? Circulation. 94:1996;I-171. Abstract.
22. Li R.K., Jia Z.Q., Weisel R.D.et al. The optimal time for cardiomyocyte transplantation after myocardial necrosis. Circulation. 94:1996;I-171. Abstract.
23. Li R.K., Mickle D.A.G., Weisel R.D., Zhang J., Mohabeer M.K. In vivo survival and function of transplanted rat cardiomyocytes. Circ Res. 78:1996;283-288.
24. Li R.K., Jia Z.Q., Weisel R.D.et al. Cardiomyocytes transplantation improves heart function. Ann Thorac Surg. 62:1996;654-661.
25. Mar J.H., McNatt J.M., Wang Y.et al. Fetal canine cardiomyocytes to enhance adult canine myocardial cell numbers. Circulation. 94:1996;I-171. Abstract.
26. Koh G.Y., Klug M.G., Soonpaa M.H., Field L.J. Differentiation and long-term survival of C2C12 myoblast grafts in heart. J Clin Invest. 92:1993;1548-1554.
27. Chiu R.C.J., Zibaitis A., Kao R.L. Cellular cardiomyoplasty: myocardial regeneration with satellite cell implantation. Ann Thorac Surg. 60:1995;12-18.
28. Yoon P.D., Kao R.L., Magovern G.J. Myocardial regeneration: transplanting satellite cells into damaged myocardium. Tex Heart Inst. 22:1995;119-125.
29. Murry C.E., Wiseman R.W., Schwartz S.M., Hauschka S.D. Skeletal myoblast transplantation for repair of myocardial necrosis. J Clin Invest. 98:1996;2512-2523.
30. Tam S.K., Gu W., Mahdavi V., Nadal-Ginard B. Cardiac myocyte terminal differentiation. Potential for cardiac regeneration. Ann NY Acad Sci. 752:1995;72-79.
31. Soonpaa M.H., Daud A.I., Koh G.Y.et al. Potential approaches for myocardial regeneration. Ann NY Acad Sci. 752:1995;446-454.
32. Sen A., Dunnmon P., Henderson S.A., Gerard R.D., Chien K.R. Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen. J Biol Chem. 263:1988;19132-19136.
33. Klung M.G., Soonpaa M.H., Koh G.Y., Field L.J. Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J Clin Invest. 98:1996;216-224.
34. Milano C.A., Allen L.F., Rockman H.A.et al. Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor. Science. 264:1994;582-586.
35. Koch W.J., Rockman H.A., Samama P.et al. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science. 268:1995;1350-1353.
36. Drazner M.H., Peppel K.C., Dyer S.et al. Potentiation of β-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes. J Clin Invest. 99:1997;288-296.
37. Ware J.A., Simons M. Angiogenesis in ischemic heart disease. Nat Med. 3:1997;158-164.
38. Morkin E. Regulation of myosin heavy chain genes in the heart. Circulation. 87:1993;1451-1460.
39. Luo W., Grupp I.L., Harrer J.et al. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res. 75:1994;401-409.
40. Yeh E.T.H. Life and death in the cardiovascular system. Circulation. 95:1997;782-786.
41. Chon J.N., Bristow M.R., Chien K.R.et al. Report of the National Heart, Lung and Blood Institute special emphasis panel on heart failure research. Circulation. 95:1997;766-770.