Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg2+ binding and efficient cleavage by hammerhead ribozyme

Biochemical and Biophysical Research Communications

Volumn 262, Issue 2, 1999, Pages 461-466

  Sioud, Mouldy ^a   Leirdal, Marianne ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYL GROUP; MAGNESIUM ION; RIBOZYME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE;

EID: 0033610024     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.1236     Document Type: Article

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