Transport kinetics of leucine enkephalin across Caco-2 monolayers: Quantitative analysis for contribution of enzymatic and transport barrier

Life Sciences

Volumn 64, Issue 14, 1999, Pages 1243-1252

  Quan, Ying Shu ^a   Fujita, Takuya ^a   Tohara, Daichi ^a   Tsuji, Miwako ^a   Kohyama, Makoto ^a   Yamamoto, Akira ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Aminopeptidases; Caco 2 cell monolayers; Clearance; Leucine enkephalin; Protease inhibitors; Transport

Indexed keywords

AMASTATIN; AMINOPEPTIDASE; BACITRACIN; GLYCOCHOLATE SODIUM; LEUCINE ENKEPHALIN; PROTEINASE INHIBITOR; PUROMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL CULTURE; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE MUCOSA; NONHUMAN; PROTEIN DEGRADATION; QUANTITATIVE DIAGNOSIS; RAT; STATISTICAL ANALYSIS;

ANIMALIA;

EID: 0033605051     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(99)00056-9     Document Type: Article

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