Analysis of proopiomelanocortin gene transcription mechanisms in bronchial tumour cells

Molecular and Cellular Endocrinology

Volumn 147, Issue 1-2, 1999, Pages 93-102

  Picon, A ^a   Bertagna, X ^a   De Keyzer, Y ^a  

^a CNRS   (France)

Author keywords

DNA binding proteins; Ectopic ACTH syndrome; Gene expression regulation; Proopiomelanocortin; SCLC

Indexed keywords

CORTICOTROPIN; DNA BINDING PROTEIN; PROOPIOMELANOCORTIN;

ARTICLE; BINDING SITE; BRONCHUS TUMOR; ECTOPIC CORTICOTROPIN PRODUCTION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN;

ACTH SYNDROME, ECTOPIC; BASE SEQUENCE; BINDING SITES; BRONCHIAL NEOPLASMS; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA FOOTPRINTING; DNA PROBES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PITUITARY GLAND; PRO-OPIOMELANOCORTIN; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0033601840     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(98)00215-9     Document Type: Article

References (38)

1. Bertagna X.Y., Nicholson W.E., Sorenson G.D., Pettengill O.S., Mount C.D., Orth D.N. Corticotropin, lipotropin and β-endorphin production by a human nonpituitary tumor in culture: evidence for a common precursor. Proc. Natl. Acad. Sci. USA. 75:1978;5160-5164.
2. Crawford M.J., Lanctôt C., Tremblay J.J., Jenkins N., Gilbert D., Copeland N., Beatty B., Drouin J. Human and murine PTX1/Ptx1 gene maps to the region for Treacher Collins syndrome. Mammal. Genome. 8:1997;841-845.
3. Drouin J., Sun Y.L., Chamberland M., Gauthier Y., De Léan A., Nemer M., Schmidt T.J. Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12:1993;145-156.
4. Drouin J., Sun Y.L., Nemer M. Regulatory elements of the pro-opiomelanocortin gene. Trends Endocrinol. Metab. 2:1990;219-225.
5. Drouin J., Trifiro M.A., Plante R.K., Nemer M., Eriksson P., Wrange O. Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol. Cell. Biol. 9:1989;5305-5314.
6. Farrell W.E., Stewart M.F., Clark A.J.L., Crosby S.R., Davis J.R.E., White A. Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells. J. Mol. Endocrinol. 10:1993;25-32.
7. Gaitan D., DeBold C.R., Turney M.K., Zhou P., Orth D.N., Kovacs W.J. Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer. Mol. Endocrinol. 9:1995;1193-1201.
8. Glass C.K. Differential recognition of target genes by nuclear receptor monomers, dimers and heterodimers. Endocr. Rev. 15:1994;391-407.
9. Hagiwara M., Alberts A., Brindle P., Meinkoth J., Feramisco J., Deng T., Karin M., Shenolikar S., Montminy M. Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. Cell. 70:1992;105-113.
10. Hedvat C.V., Irving S.G. The isolation and characterization of MINOR, a novel mitogen-inducible nuclear orphan receptor. Mol. Endocrinol. 9:1995;1692-1700.
11. Helin K., Wu C.-L., Fattaey A.R., Lees J.A., Dynlacht B.D., Ngwu C., Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative transactivation. Genes Dev. 7:1993;1850-1861.
12. Kraus J., Buchfelder M., Höllt V. Regulatory elements of the human proopiomelanocortin gene promoter. DNA Cell Biol. 12:1993;527-536.
13. Kraus J., Höllt V. Identification of a cAMP-response element on the human proopiomelanocortin gene upstream promoter. DNA Cell Biol. 14:1995;103-110.
14. Lamonerie T., Tremblay J.J., Lanctôt C., Therrien M., Gauthier Y., Drouin J. Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes Dev. 10:1996;1284-1295.
15. Lee J.E., Hollenberg S.M., Snider L., Turner D.L., Lipnick N., Weintraub H. Conversion of xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science. 268:1995;836-844.
16. Liu B., Hammer G.D., Rubinstein M., Mortrud M., Low M.J. Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice. Mol. Cell. Biol. 12:1992;3978-3990.
17. Liu B., Mortrud M., Low M.J. DNA elements with AT-rich core sequences direct pituitary cell-specific expression of the pro-opiomelanocortin gene in transgenic mice. Biochem. J. 312:1995;827-832.
18. Maxam A.M., Gilbert W. Sequencing end-labelled DNA with base-specific chemical cleavages. Methods Enzymol. 65:1980;499-560.
19. Murphy E.P., Conneely O.M. Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nurr77 subfamily of nuclear receptors. Mol. Endocrinol. 11:1997;39-47.
20. Nakai A., Kartha S., Sakurai A., Toback G.F., DeGroot L.J. A human early response gene homologous to murine nur77 and rat NGFI-B and related to the nuclear receptor superfamily. Mol. Endocrinol. 4:1990;1438-1443.
21. Naya F.J., Stellrecht M.M., Tsai M.-J. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 9:1995;1009-1019.
22. Nordeen S.K. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques. 6:1988;454-457.
23. Okabe T., Takayanagi R., Adachi M., Imasaki K., Nawata H. Nur77, a member of the steroid receptor superfamily, antagonizes negative feedback of ACTH synthesis and secretion by glucocorticoid in pituitary corticotrope cells. J. Endocrinol. 156:1998;169-175.
24. Okabe T., Takayanagi R., Imasaki K., Haji M., Nawata H., Watanabe T. cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line. J. Immunol. 154:1995;3871-3879.
25. Philips A., Lesage S., Gingras R., Maira M.-H., Gauthier Y., Hugo P., Drouin J. Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells. Mol. Cell. Biol. 17:1997a;5946-5951.
26. Philips A., Maira M., Mullick A., Chamberland M., Lesage S., Hugo P., Drouin J. Antagonism between Nur77 and Glucocorticoid Receptor for control of transcription. Mol. Cell. Biol. 17:1997b;5952-5959.
27. Picon A., Leblond-Francillard M., Raffin-Sanson M.-L., Lenne F., Bertagna X., de Keyzer Y. Functional analysis of the human proopiomelanocortin promoter in the small cell lung carcinoma cell line DMS-79. J. Mol. Endocrinol. 15:1995;187-194.
28. Poulin G., Turgeon B., Drouin J. NeuroD1/b2 contributes to cell-specific transcription of the proopiomelanocortin gene. Mol. Cell. Biol. 17:1997;6673-6682.
29. Ray D.W., Littlewood A.C., Clark A.J.L., Davis J.R.E., White A. Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function. J. Clin. Invest. 93:1994;1625-1630.
30. Raymondjean M., Cereghini S., Yaniv M. Several distinct 'CCAAT' box binding proteins coexist in eukaryotic cells. Proc. Natl. Acad. Sci. USA. 85:1988;757-761.
31. Sambrook J., Fritsch E.F., Maniatis T. Molecular cloning: A laboratory manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
32. Therrien M., Drouin J. Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements. Mol. Cell. Biol. 11:1991;3492-3503.
33. Therrien M., Drouin J. Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene. Mol. Cell. Biol. 13:1993;2342-2353.
34. Thomas M., Skala H., Kahn A., Phan Dinh Tuy F. Functional dissection of the brain-specific rat aldolase C gene promoter in transgenic mice. J. Biol. Chem. 270:1995;20316-20321.
35. Tsukada T., Nakai Y., Fukushima M., Usui T., Imura H., Takebe H. Functional analysis of the cell-specific enhancer in the human proopiomelanocortin gene by b-galactosidase histochemical staining. DNA Cell. Biol. 13:1994;755-762.
36. Vaulont S., Puzenat N., Levrat F., Cognet M., Kahn A., Raymondjean M. Proteins binding to the liver-specific pyruvate kinase gene promoter A unique combination of known factors. J. Mol. Biol. 209:1989;205-219.
37. Wilson T.E., Fahrner T.J., Johnston M., Milbrandt J. Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science. 252:1991;1296-1300.
38. Yokoyama M., Nishi Y., Miyamoto Y., Nakamura M., Akiyama K., Matsubara K., Okubo K. Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum. Brain Res. Mol. Brain Res. 42:1996;135-139.