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Volumn 66, Issue 7, 1998, Pages 3378-3383

Identification of three highly attenuated Salmonella typhimurium mutants that are more immunogenic and protective in mice than a prototypical aroA mutant

Author keywords

[No Author keywords available]

Indexed keywords

SALMONELLOSIS VACCINE;

EID: 0031844796     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.7.3378-3383.1998     Document Type: Article
Times cited : (48)

References (38)
  • 1
    • 0028215784 scopus 로고
    • Salmonella typhimurium loci involved in survival within macrophages
    • Baumler, A. J., J. G. Kusters, I. Stojiljkovic, and F. Heffron. 1994. Salmonella typhimurium loci involved in survival within macrophages. Infect. Immun. 62:1623-1630.
    • (1994) Infect. Immun. , vol.62 , pp. 1623-1630
    • Baumler, A.J.1    Kusters, J.G.2    Stojiljkovic, I.3    Heffron, F.4
  • 3
    • 0031869632 scopus 로고    scopus 로고
    • At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice
    • Bowe, F., C. J. Lipps, R. M. Tsolis, E. Groisman, F. Heffron, and J. G. Kusters. 1998. At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice. Infect. Immun. 66:3372-3377.
    • (1998) Infect. Immun. , vol.66 , pp. 3372-3377
    • Bowe, F.1    Lipps, C.J.2    Tsolis, R.M.3    Groisman, E.4    Heffron, F.5    Kusters, J.G.6
  • 4
    • 0029073731 scopus 로고
    • Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes
    • Burland, V., G. R. Plunkett, H. J. Sofia, D. L. Daniels, and F. R. Blattner. 1995. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Nucleic Acids Res. 23:2105-2119.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2105-2119
    • Burland, V.1    Plunkett, G.R.2    Sofia, H.J.3    Daniels, D.L.4    Blattner, F.R.5
  • 5
    • 0026810652 scopus 로고
    • Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model
    • Chatfield, S. N., K. Strahan, D. Pickard, I. G. Charles, C. E. Hormaeche, and G. Dougan. 1992. Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model. Microb. Pathog. 12:145-151.
    • (1992) Microb. Pathog. , vol.12 , pp. 145-151
    • Chatfield, S.N.1    Strahan, K.2    Pickard, D.3    Charles, I.G.4    Hormaeche, C.E.5    Dougan, G.6
  • 6
    • 0023491110 scopus 로고
    • Salmonella typhimurium deletion mutants lacking adenylate cyclase and cyclic AMP receptor protein are avirulent and immunogenic
    • Curtiss, R., III, and S. M. Kelly. 1987. Salmonella typhimurium deletion mutants lacking adenylate cyclase and cyclic AMP receptor protein are avirulent and immunogenic. Infect. Immun. 55:3035-3043.
    • (1987) Infect. Immun. , vol.55 , pp. 3035-3043
    • Curtiss III, R.1    Kelly, S.M.2
  • 8
    • 0024399678 scopus 로고
    • Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: OmpR mutants are attenuated in vivo
    • Dorman, C. J., S. Chatfield, C. F. Higgins, C. Hayward, and G. Dougan. 1989. Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo. Infect. Immun. 57:2136-2140.
    • (1989) Infect. Immun. , vol.57 , pp. 2136-2140
    • Dorman, C.J.1    Chatfield, S.2    Higgins, C.F.3    Hayward, C.4    Dougan, G.5
  • 9
    • 0024232212 scopus 로고
    • Construction and characterisation of Salmonella vaccine strains harbouring mutations in two different aro genes
    • Dougan, G., S. N. Chatfield, D. Pickard, D. O'Callaghan, and D. Maskell. 1988. Construction and characterisation of Salmonella vaccine strains harbouring mutations in two different aro genes. J. Infect. Dis. 158:1329-1335.
    • (1988) J. Infect. Dis. , vol.158 , pp. 1329-1335
    • Dougan, G.1    Chatfield, S.N.2    Pickard, D.3    O'Callaghan, D.4    Maskell, D.5
  • 11
    • 0029057492 scopus 로고
    • Live Salmonella vaccines as a route towards oral immunisations
    • Everest, P., P. Griffiths, and G. Dougan. 1995. Live Salmonella vaccines as a route towards oral immunisations. Biologicals 23:119-124.
    • (1995) Biologicals , vol.23 , pp. 119-124
    • Everest, P.1    Griffiths, P.2    Dougan, G.3
  • 12
    • 0011736531 scopus 로고
    • Mutants of Salmonella typhimurium that cannot survive inside macrophages are avirulent
    • Fields, P. I., R. V. Swanson, C. G. Heidaris, and F. Heffron. 1986. Mutants of Salmonella typhimurium that cannot survive inside macrophages are avirulent. Proc. Natl. Acad. Sci. USA 83:5189-5193.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5189-5193
    • Fields, P.I.1    Swanson, R.V.2    Heidaris, C.G.3    Heffron, F.4
  • 13
    • 0024382180 scopus 로고
    • Common themes in microbial pathogenicity
    • Finlay, B. B., and S. Falkow. 1989. Common themes in microbial pathogenicity. Microbiol. Rev. 53:210-230.
    • (1989) Microbiol. Rev. , vol.53 , pp. 210-230
    • Finlay, B.B.1    Falkow, S.2
  • 14
    • 0024115123 scopus 로고
    • Identification and characterization of TnphoA mutants of Salmonella which are unable to penetrate through a polarized MDCK epithelial cell monolayer
    • Finlay, B. B., M. N. Starnbach, C. Francis, B. A. D. Stocker, S. N. Chatfield, G. Dougan, and S. Falkow. 1988. Identification and characterization of TnphoA mutants of Salmonella which are unable to penetrate through a polarized MDCK epithelial cell monolayer. Mol. Microbiol. 2:757-766.
    • (1988) Mol. Microbiol. , vol.2 , pp. 757-766
    • Finlay, B.B.1    Starnbach, M.N.2    Francis, C.3    Stocker, B.A.D.4    Chatfield, S.N.5    Dougan, G.6    Falkow, S.7
  • 15
    • 0023410503 scopus 로고
    • tolA, tolB and excC, three cistrons involved in the control of pleiotropic release of periplasmic proteins by Escherichia coli K12
    • Fognini-Lefebvre, N., J. C. Lazzaroni, and R. Portalier. 1987. tolA, tolB and excC, three cistrons involved in the control of pleiotropic release of periplasmic proteins by Escherichia coli K12. Mol. Gen. Genet. 209:391-395.
    • (1987) Mol. Gen. Genet. , vol.209 , pp. 391-395
    • Fognini-Lefebvre, N.1    Lazzaroni, J.C.2    Portalier, R.3
  • 16
    • 0024445956 scopus 로고
    • Virulence and vaccine potential of phoP mutants of Salmonella typhimurium
    • Galan, J. E., and R. Curtiss III. 1989. Virulence and vaccine potential of phoP mutants of Salmonella typhimurium. Microb. Pathog. 6:433-443.
    • (1989) Microb. Pathog. , vol.6 , pp. 433-443
    • Galan, J.E.1    Curtiss III, R.2
  • 17
    • 0016822485 scopus 로고
    • Isolation and characterization of a galE mutant Ty21a of Salmonella typhi: A candidate strain for a live oral typhoid vaccine
    • Germanier, R., and E. Fuer. 1975. Isolation and characterization of a galE mutant Ty21a of Salmonella typhi: a candidate strain for a live oral typhoid vaccine. J. Infect. Dis. 131:553-558.
    • (1975) J. Infect. Dis. , vol.131 , pp. 553-558
    • Germanier, R.1    Fuer, E.2
  • 19
    • 0029117137 scopus 로고
    • Simultaneous identification of bacterial virulence genes by negative selection
    • Hensel, M., J. E. Shea, C. Gleeson, M. D. Jones, E. Dalton, and D. W. Holden. 1995. Simultaneous identification of bacterial virulence genes by negative selection. Science 269:400-403.
    • (1995) Science , vol.269 , pp. 400-403
    • Hensel, M.1    Shea, J.E.2    Gleeson, C.3    Jones, M.D.4    Dalton, E.5    Holden, D.W.6
  • 20
    • 0029799771 scopus 로고    scopus 로고
    • PhoP/ phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers
    • Hohmann, E. L., C. A. Oletta, K. P. Killeen, and S. I. Miller. 1996. phoP/ phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers. J. Infect. Dis. 173:1408-1414.
    • (1996) J. Infect. Dis. , vol.173 , pp. 1408-1414
    • Hohmann, E.L.1    Oletta, C.A.2    Killeen, K.P.3    Miller, S.I.4
  • 21
    • 0030028340 scopus 로고
    • Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers
    • Hohmann, E. L., C. A. Oletta, and S. I. Miller. 1995. Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers. Vaccine 14:19-24.
    • (1995) Vaccine , vol.14 , pp. 19-24
    • Hohmann, E.L.1    Oletta, C.A.2    Miller, S.I.3
  • 22
    • 0026042415 scopus 로고
    • Construction of genetically defined double aro mutants of Salmonella typhi
    • Hone, D. M., A. M. Harris, S. Chatfield, G. Dougan, and M. M. Levine. 1991. Construction of genetically defined double aro mutants of Salmonella typhi. Vaccine 9:810-816.
    • (1991) Vaccine , vol.9 , pp. 810-816
    • Hone, D.M.1    Harris, A.M.2    Chatfield, S.3    Dougan, G.4    Levine, M.M.5
  • 23
    • 0028850329 scopus 로고
    • Differential induction of carrier antigen-specific immunity by Salmonella typhimurium live-vaccine strains after single mucosal or intravenous immunization of BALB/c mice
    • Karem, K. L., S. Chatfield, N. Kuklin, and B. T. Rouse. 1995. Differential induction of carrier antigen-specific immunity by Salmonella typhimurium live-vaccine strains after single mucosal or intravenous immunization of BALB/c mice. Infect. Immun. 63:4557-4563.
    • (1995) Infect. Immun. , vol.63 , pp. 4557-4563
    • Karem, K.L.1    Chatfield, S.2    Kuklin, N.3    Rouse, B.T.4
  • 24
    • 0026345034 scopus 로고
    • Intracellular replication is essential for the virulence of Salmonella typhimurium
    • Leung, K. Y., and B. B. Finlay. 1991. Intracellular replication is essential for the virulence of Salmonella typhimurium. Proc. Natl. Acad. Sci. USA 88: 11470-11474.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11470-11474
    • Leung, K.Y.1    Finlay, B.B.2
  • 25
    • 0023180351 scopus 로고
    • Large-scale field trial of Ty21a live oral typhoid vaccine in enteric coated capsule formulation
    • Levine, M. M., C. Ferriccio, R. E. Black, and R. Germanier. 1987. Large-scale field trial of Ty21a live oral typhoid vaccine in enteric coated capsule formulation. Lancet i:1049-1052.
    • (1987) Lancet , vol.1 , pp. 1049-1052
    • Levine, M.M.1    Ferriccio, C.2    Black, R.E.3    Germanier, R.4
  • 26
    • 0025630592 scopus 로고
    • Clinical and field trials with attenuated Salmonella typhi as live oral vaccines and as "carrier" vaccines
    • Levine, M. M., D. Hone, C. Tacket, C. Ferreccio, and S. Cryz. 1990. Clinical and field trials with attenuated Salmonella typhi as live oral vaccines and as "carrier" vaccines. Res. Microbiol. 141:807-816.
    • (1990) Res. Microbiol. , vol.141 , pp. 807-816
    • Levine, M.M.1    Hone, D.2    Tacket, C.3    Ferreccio, C.4    Cryz, S.5
  • 27
    • 0027497926 scopus 로고
    • Selection of bacterial virulence genes that are specifically induced in host tissues
    • Mahan, M. J., J. M. Slauch, and J. J. Mekalanos. 1993. Selection of bacterial virulence genes that are specifically induced in host tissues. Science 259:686-688.
    • (1993) Science , vol.259 , pp. 686-688
    • Mahan, M.J.1    Slauch, J.M.2    Mekalanos, J.J.3
  • 28
    • 0025609076 scopus 로고
    • Salmonella vaccines with mutations in the phoP virulence regulon
    • Miller, S. I., J. J. Mekalanos, and W. S. Pulkkinen. 1990. Salmonella vaccines with mutations in the phoP virulence regulon. Res. Microbiol. 141: 817-821.
    • (1990) Res. Microbiol. , vol.141 , pp. 817-821
    • Miller, S.I.1    Mekalanos, J.J.2    Pulkkinen, W.S.3
  • 29
    • 0023853960 scopus 로고
    • Characterization of aromatic- and purine-dependent Salmonella typhimurium: Attenuation, persistence, and ability to induce protective immunity in BALB/c mice
    • O'Callaghan, D., D. Maskell, F. Y. Liew, C. S. F. Easmon, and G. Dougan. 1988. Characterization of aromatic- and purine-dependent Salmonella typhimurium: attenuation, persistence, and ability to induce protective immunity in BALB/c mice. Infect. Immun. 56:419-423.
    • (1988) Infect. Immun. , vol.56 , pp. 419-423
    • O'Callaghan, D.1    Maskell, D.2    Liew, F.Y.3    Easmon, C.S.F.4    Dougan, G.5
  • 30
    • 33745158157 scopus 로고
    • A simple method for estimating fifty percent endpoints
    • Reed, L. J., and H. Muench. 1938. A simple method for estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 31
    • 0029189404 scopus 로고
    • Salmonellae as oral vaccine carriers
    • Schodel, F., and R. Curtiss III. 1995. Salmonellae as oral vaccine carriers. Dev. Biol. Stand. 84:245-253.
    • (1995) Dev. Biol. Stand. , vol.84 , pp. 245-253
    • Schodel, F.1    Curtiss III, R.2
  • 32
    • 0024356474 scopus 로고
    • Effect of a pura mutation on efficacy of Salmonella live-vaccine vectors
    • Sigwart, D. F., B. A. D. Stocker, and J. D. Clements. 1989. Effect of a purA mutation on efficacy of Salmonella live-vaccine vectors. Infect. Immun. 57: 1858-1861.
    • (1989) Infect. Immun. , vol.57 , pp. 1858-1861
    • Sigwart, D.F.1    Stocker, B.A.D.2    Clements, J.D.3
  • 35
    • 0026521261 scopus 로고
    • Clinical acceptability and immunogenicity of CVD908 Salmonella typhi vaccine strain
    • Tacket, C. O., D. M. Hone, G. A. Losonsky, L. Guers, R. Edelman, and M. M. Levine. 1992. Clinical acceptability and immunogenicity of CVD908 Salmonella typhi vaccine strain. Vaccine 10:443-446.
    • (1992) Vaccine , vol.10 , pp. 443-446
    • Tacket, C.O.1    Hone, D.M.2    Losonsky, G.A.3    Guers, L.4    Edelman, R.5    Levine, M.M.6
  • 37
    • 0029669978 scopus 로고    scopus 로고
    • Induction of SIV capsid-specific CTL and mucosal sIgA in mice immunized with a recombinant S. typhimurium aroA mutant
    • Valentine, P. J., K. Meyers, M. M. Rivera, C. Lipps, D. Pauza, R. T. Maziarz, M. So, and F. Heffron. 1996. Induction of SIV capsid-specific CTL and mucosal sIgA in mice immunized with a recombinant S. typhimurium aroA mutant. Vaccine 14:138-146.
    • (1996) Vaccine , vol.14 , pp. 138-146
    • Valentine, P.J.1    Meyers, K.2    Rivera, M.M.3    Lipps, C.4    Pauza, D.5    Maziarz, R.T.6    So, M.7    Heffron, F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.