Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains

Journal of Biological Chemistry

Volumn 274, Issue 34, 1999, Pages 24074-24079

  Coombs, Gary S ^b   Rao, Mohan S ^a   Olson, Arthur J ^a   Dawson, Philip E ^a   Madison, Edwin L ^a,b,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Dendreon   (United States)

^c TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN; SERINE PROTEINASE;

ARTICLE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

BINDING SITES; CATALYSIS; HYDROGEN BONDING; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN INHIBITORS;

EID: 0033588099     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.34.24074     Document Type: Article

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