Efficient gene transfer by hybrid retroviral vectors to murine spermatogenic cells

Human Gene Therapy

Volumn 10, Issue 11, 1999, Pages 1819-1831

  Danno, Shozo ^a,b   Itoh, Katsuhiko ^a   Baum, Christopher ^c   Ostertag, Wolfram ^c   Ohnishi, Naoki ^a   Kido, Tsuneo ^a   Tomiwa, Kiyotaka ^a   Matsuda, Tadashi ^b   Fujita, Jun ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; ENHANCER REGION; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; LONG TERMINAL REPEAT; MOLONEY LEUKEMIA ONCOVIRUS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PROMOTER REGION; REPRESSOR GENE; RETROVIRUS; SPERMATOCYTE; SPERMATOGENESIS; VIRUS HYBRID;

ANIMALS; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; COLCHICINE; FLOW CYTOMETRY; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENES, MDR; GENES, REPORTER; GENETIC VECTORS; MALE; MICE; PLASMIDS; RETROVIRIDAE; RHODAMINES; SPERMATOGENESIS; SPERMATOZOA; TRANSDUCTION, GENETIC;

ANIMALIA; FELIS CATUS; MOLONEY MURINE LEUKEMIA VIRUS; MURINAE; MYELOPROLIFERATIVE SARCOMA VIRUS; ONCOVIRINAE; SPLEEN FOCUS-FORMING VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0033587651     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950017509     Document Type: Article

References (42)

1. AKGUEN, E., ZIEGLER, M., and GREZ, M. (1991). Determinants of retrovirus gene expression in embryonal carcinoma cells. J. Virol. 65, 382-388.
2. ALBRITTON, L.M., TSENG, L., SCADDEN, D., and CUNNINGHAM, J.M. (1989). A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57, 659-666.
3. BAUM, C., HEGEWISCH-BECKER, S., ECKERT, H., STOCKING, C., and OSTERTAG, W. (1995). Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells. J. Virol. 69, 7541-7547.
4. BAUM, C., ECKERT, H.G., STOCKING, C., and OSTERTAG, W. (1996). Activity of Friend mink cell focus-forming retrovirus during myelo-erythroid hematopoiesis. Exp. Hematol. 24, 364-370.
5. BAUM, C., ITOH, K., MEYER, J., LAKER, C., ITO, Y., and OSTERTAG, W. (1997). The potent enhancer activity of the polycythemic strain of spleen focus-forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PEBP/CBF. J. Virol. 71, 6323-6331.
6. BECK-ENGESER, G., STOCKING, C., JUST, U., ALBITTRON, L., DEXTER, M., SPOONCER, E., and OSTERTAG, W. (1991). Retroviral vectors related to the myeloproliferative sarcoma virus allow efficient expression in hematopoietic stem and progenitor cell lines, but retroviral infection is reduced in more primitive cells. Hum. Gene Ther. 2, 61-70.
7. BLANCHARD, K.T., and BOEKELHEIDE, K. (1997). Adenovirus-mediated gene transfer to rat testis in vivo. Biol. Reprod. 56, 495-500.
8. BRINSTER, R.L., and AVARBOCK, M.R. (1994). Germline transmission of donor haplotype following spermatogonial transplantation. Proc. Natl. Acad. Sci. U.S.A. 91, 11303-11307.
9. CHALLITA, P.M., and KOHN, D.B. (1994). Lack of expression from a retroviral vector after transduction of murine hematopoietic cells is associated with methylation in vivo. Proc. Natl. Acad. Sci. U.S.A. 91, 2567-2571.
10. COLICELLI, J., and GOFF, S.P. (1987). Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA. J. Virol. 57, 37-45.
11. DIRKS, W., WIRTH, M., and HAUSER, H. (1993). Dicistronic transcription units for gene expression in mammalian cells. Gene 128, 246-259.
12. ECKERT, H.G., STOCKSCHLADER, M., JUST, U., HEGEWISCHBEKER, S., GREZ, M., UHDE, A., ZANDER, A., OSTERTAG, W., and BAUM, C. (1996). High-dose multidrug resistance in primary human hematopoietic progenitor cells transduced with optimized retrovirus vector. Blood 88, 3407-3415.
13. GREZ, M., AKGUEN, E., HILBERG, F., and OSTERTAG, W. (1990). Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 87, 9202-9206.
14. GREZ, M., ZOERNIG, M., NOWOCK, J., and ZIEGLER, M. (1991). A single point mutation activates the Molony murine leukemia virus long terminal repeat in embryonal stem cells. J. Virol. 65, 4691-4698.
15. HANANIA, E.G., and DEISSEROTH, A.B. (1994). Serial transplantation shows that early hematopoietic precursor cells are transduced by MDR-1 retroviral vector in a mouse gene therapy model. Cancer Gene Ther. 1, 21-25.
16. HILBERG, F., STOCKING, C., OSTERTAG, W., and GREZ, M. (1987). Functional analysis of a retroviral host-range mutant: Altered long terminal repeat sequences allow expression in embryonal carcinoma cells. Proc. Natl. Acad. Sci. U.S.A. 84, 5232-5236.
17. HILDINGER, M., FEHSE, B., HEGEWISCH-BECKER, S., JOHN, J., RAFFERTY, J.R., OSTERTAG, W., and BAUM, C. (1998). Dominant selection of hematopoietic progenitor cells with retroviral MDR1 co-expression vectors. Hum. Gene Ther. 9, 33-42.
18. HITOSHI, Y., LORENS, J., FISHER, J., LABARGE, M., RING, H.Z., FRANCHE, U., KITADA, S., REED, J.C., KINOSHITA, S., and NOLAN, G.P. (1998). Toso, a cell-surface specific regulator of Fas-induced apoptosis in T-cells. Immunity 4, 461-471.
19. HOFMANN, M.C., NARISAWA, S., HESS, R.A., and MILLAN, J.L. (1992). Immortalization of germ cells and somatic testicular cells using the SV40 large T antigen. Exp. Cell Res. 201, 417-435.
20. HOFMANN, M.C., HESS, R.A., GOLDBERG, E., and MILLAN, J.L. (1994). Immortalized germ cells undergo meiosis in vitro. Proc. Natl. Acad. Sci. U.S.A. 91, 5533-5537.
21. ITOH, K., FRIEL, J., KLUGE, N., KINA, T., KONDO-TAKAORI, A., KAWAMATA, S., UCHIYAMA, T., and OSTERTAG, W. (1996). A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell-dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction. Blood 87, 3218-3228.
22. JAINCHILL, J.L., AARONSON, S.A., and TODARO, G.J. (1969). Murine sarcoma and leukemia viruses: Assay using clonal lines of contact-inhibited mouse cells. J. Virol. 4, 549-553.
23. KEMPLER, G., FREITAG, B., BERWIN, B., NANASSY, Q., and BARKLIS, E. (1993). Characterization of the Moloney murine leukemia virus stem cell-specific repressor primer binding site. Virology 193, 690-699.
24. KINGSTON, R.E., OKAYAMA, H., CHEN, C.A., and ROSE, J.K. (1997). Calcium phosphate transfection. In Current Protocols in Molecular Biology. F.M. Ausubel, R. Brent, R.E. Kingston, and D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl, eds. (John Wiley & Sons, New York) pp. 9.1.4-9.1.11.
25. KITAMURA, T. (1998). New experimental approaches in retrovirus-mediated expression screening. Int. J. Hematol. 67, 351-359.
26. LI, Y., GOLEMIS, E., HARTLEY, J.W., and HOPKINS, N. (1987). Disease specificity of nondefective Friend and Moloney murine leukemia virus is controlled by a small number of nucleotides. J. Virol. 61, 693-700.
27. LUDESCHER, C., THALER, J., DRACH, D., DRACH, J., SPITALER, M., GATTRINGER, C., HAUBER, H., and HOFMANN, J. (1992). Detection of activity of P-glycoprotein in human tumor samples using rhodamine 123. Br. J. Haematol. 82, 161-168.
28. MARKOWITZ, D., GOFF, S., and BANK, A. (1988a). A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62, 1120-1124.
29. MARKOWITZ, D., GOFF, S., and BANK, A. (1988b). Construction and use of a safe and efficient amphotropic packaging cell line. Virology 167, 400-406.
30. MILLER, D.G., EDWARD, R.H., and MILLER, D. (1994). Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus. Proc. Natl. Acad. Sci. U.S.A. 91, 78-82.
31. NISHIYAMA, H., HIGASHITSUJI, H., YOKOI, H., ITOH, K., DANNO, S., MATSUDA, T., and FUJITA, J. (1997). Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene. Gene 204, 115-120.
32. ORLIC, D., GIRARD, L.J., JORDAN, C.T., ANDERSON, S.M., CLINE, A.P., and BODINE, D.M. (1996). The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction. Proc. Natl. Acad. Sci. U.S.A. 93, 11097-11102.
33. OSTERTAG, W., STOCKING, C., JOHNSON, G.R., KLUGE, N., KOLLEK, R., FRANZ, T., and HESS, N. (1987). Transforming genes and target cells of murine spleen focus-forming viruses. Adv. Cancer. Res. 48, 193-355.
34. RICHARDSON, C., and BANK, A. (1996). Developmental-stage-specific expression and regulation of an amphotropic retroviral receptor in hematopoietic cells. Mol. Cell. Biol. 16, 4240-4247.
35. SIMONI, M. (1994). Transgenic animals in male reproductive research. Exp. Clin. Endocrinol. 102, 419-433.
36. SPECK, N.A., RENJIFO, B.V., GOLEMLS, F., FREDRICKSON, T.N., HARTLEY, J.W., and HOPKINS, N. (1990). Mutation of the core or adjacent LVb elements of the Moloney leukemia virus enhancer alters disease specificity. Genes Dev. 4, 223-242.
37. STOCKING, C., KOLLEK, R., BERGHOLZ, U., and OSTERTAG, W. (1985). Long-terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus. Proc. Natl. Acad. Sci. U.S.A. 82, 5746-5750.
38. UCHIYAMA, T., BRODER, S., and WALDMNN, T.A. (1981). A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. J. Immunol. 126, 1393-1397.
39. VON LAER, D., THOMSEN, S., VOGT, B., DONATH, M., KRUPPA, J., REIN, A., OSTERTAG, W., and STOCKING, C. (1998). Entry of amphotropic and 10A1 pseudotyped murine retroviruses is restricted in hematopoietic stem cell lines. J. Virol. 72, 1424-1430.
40. YAMAUCHI, M., FREITAG, B., KHAN, C., BERWIN, B., and BARKLIS, E. (1995). Stem cell factor binding to retrovirus primer binding site silencers. J. Virol. 69, 1142-1149.
41. YAMAZAKI, Y., FUJIMOTO, H., ANDO, H., OHYAMA, T., HIROTA, Y., and NOSE, T. (1998). In vivo gene transfer to mouse spermatogenic cells by deoxyribonucleic acid injection into seminiferous tubules and subsequent electroporation. Biol. Reprod. 59, 1439-1444.
42. ZIRKIN, B.R. (1993). Regulation of spermatogenesis in the adult mammal: Gonadotropins and androgens. In Cell and Molecular Biology of the Testis. C. Desjardins and L.L. Ewing, eds. (Oxford University Press, New York) pp. 166-188.