Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia

Human Gene Therapy

Volumn 10, Issue 5, 1999, Pages 801-811

  Machiels, Jean Pascal ^a   Govaerts, Anne Sophie ^a   Guillaume, Thierry ^a   Bayat, Babak ^a   Feyens, Anne Marie ^a   Lenoir, Elisabeth ^a   Goeminne, Jean Charles ^a   Cole, Susan ^b   Deeley, Roger ^b   Caruso, Manuel ^c   Bank, Arthur ^d   Symann, Michel ^a   D'Hondt, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b QUEEN S UNIVERSITY   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; PHOSPHOGLYCERATE KINASE;

ANIMAL CELL; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER MORTALITY; CELL PROTECTION; CELL SELECTION; COCULTURE; CONTROLLED STUDY; ECOTROPIC VIRUS; FLUORESCENCE ANALYSIS; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; IRRADIATION; LEUKOPENIA; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PERIPHERAL BLOOD STEM CELL; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROVIRUS; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; VIRUS RECOMBINANT;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, SOUTHERN; BONE MARROW CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKOCYTES; LEUKOPENIA; MALE; MICE; MICE, INBRED C57BL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

ANIMALIA; MURINAE; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0033586247     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950018553     Document Type: Article

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