Differential inhibition of HMG-CoA synthase and pancreatic lipase by the specific chiral isomers of β-lactone DU-6622

Biochemical and Biophysical Research Communications

Volumn 265, Issue 2, 1999, Pages 536-540

  Tomoda, Hiroshi ^a   Ohbayashi, Naomi ^a   Kumagai, Hidetoshi ^a   Hashizume, Hirokazu ^b   Sunazuka, Toshiaki ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b FUJI CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A (HMG CoA) synthase; Enzyme inhibitor; Pancreatic lipase; lactone

Indexed keywords

12 HYDROXY 13 HYDROXYMETHYL 3,5,7 TRIMETHYLTETRADECA 2,4 DIENEDIOIC ACID 12,14 LACTONE; CARBON 14; ENZYME INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LACTONE DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHIRALITY; CONTROLLED STUDY; ISOMER; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0033585099     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.1712     Document Type: Article

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