Motor effects and mapping of cerebral alterations in animal models of Parkinson's and Huntington's diseases

Journal of Comparative Neurology

Volumn 410, Issue 1, 1999, Pages 99-114

  Hebb, M O ^a   Robertson, H A ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Basal ganglia; c Fos; Movement disorders; Rotation

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; APOMORPHINE; DEXAMPHETAMINE; OXIDOPAMINE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN CORTEX; BRAIN FUNCTION; BRAIN REGION; CIRCLING BEHAVIOR; FEMALE; HUNTINGTON CHOREA; IMMUNOREACTIVITY; MALE; MOTOR DYSFUNCTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; RAT; ROTATION;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN MAPPING; CORPUS STRIATUM; DEXTROAMPHETAMINE; DISEASE MODELS, ANIMAL; DOPAMINE; FEMALE; HUNTINGTON DISEASE; MALE; MOTOR ACTIVITY; OLIGONUCLEOTIDES, ANTISENSE; OXIDOPAMINE; PARKINSON DISEASE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TISSUE DISTRIBUTION;

EID: 0033584256     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19990719)410:1<99::AID-CNE9>3.0.CO;2-E     Document Type: Article

References (65)

1. Agid Y. 1991. Parkinson's disease: pathophysiology. Lancet 337:1321-1324.
2. Avanzini G, Girotti F, Caraceni T, Spreafico R. 1979. Oculomotor disorders in Huntington's chorea. J Neurol Neurosurg Psychiatr 42:581-589.
3. Berthoz A, Grantyn A. 1986. Neural mechanisms underlying eye-head coordination. Progr Brain Res 64:325-343.
4. Bickford ME, Hall WC. 1992. The nigral projection to predorsal bundle cells in the superior colliculus of the rat. J Comp Neurol 319:11-33.
5. Biggs CS, Fowler LJ, Whitton PS, Starr MS. 1997. Extracellular levels of glutamate and aspartate in the entopeduncular nucleus of the rat determined by microdialysis: regulation by striatal dopamine D2 receptors via the indirect striatal output pathway? Brain Res 753:163-175.
6. Black KJ, Gado MH, Perlmutter JS. 1997. PET measurement of dopamine D2 receptor-mediated changes in striatopallidal function. J Neurosci 17:3168-3177.
7. Chiasson B, Hooper M, Murphy P, Robertson H. 1992. Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. Eur J Pharmacol 227:451-453.
8. Chiasson B, Armstrong J, Hooper M, Murphy P, Robertson H. 1994. The application of antisense oligonucleotide technology to the brain: some pitfalls. Cell Mol Neurobiol 14:507-521.
9. Dean P, Redgrave P. 1992. Behavioral consequences of manipulating GABA neurotransmission in the superior colliculus. Progr Brain Res 90:263-281.
10. Dean P, Redgrave P, Sahibzada N, Tsuji K. 1986. Head and body movements produced by stimulation of the superior colliculus in rats: effects of interruption of the crossed tectoreticulospinal pathway. Neuroscience 19:367-380.
11. Dean P, Mitchell IJ, Redgrave P. 1988. Responses resembling defensive behavior produced by microinjection of glutamate into superior colliculus of rats. Neuroscience 24:501-510.
12. Dragunow M, Faull R. 1989. The use of c-fos as a metabolic marker in neuronal pathway tracing. J Neurosci Methods 29:261-265.
13. Dragunow M, Lawlor P, Chiasson B, Robertson H. 1993. C-fos antisense generates apomorphine and amphetamine-induced rotation. Neuroreport 5:305-306.
14. Dragunow M, Tse C, Glass M, Lawlor P. 1994. C-fos antisense reduces expression of Krox 24 in rat caudate and neocortex. Cell Mol Neurobiol 14:395-405.
15. Dreher B, Sefton AJ, Ni SK, Nisbett G. 1985. The morphology, number, distribution and central projections of class I retinal ganglion cells in albino and hooded rats. Brain Behav Evol 26:10-48.
16. Ellard CG, Goodale MA. 1986. The role of the predorsal bundle in head and body movements elicited by electrical stimulation of the superior colliculus in the Mongolian gerbil. Exp Brain Res 64:421-433.
17. Ellard CG, Goodale MA. 1988. A functional analysis of the collicular output pathways: a dissociation of deficits following lesions of the dorsal tegmental decussation and the ipsilateral collicular efferent bundle in the Mongolian gerbil. Exp Brain Res 71:307-319.
18. Finkelstein DI, Reeves AK, Horne MK. 1996. An electron microscopic tracer study of the projections from entopeduncular nucleus to the ventrolateral nucleus of the rat. Neurosci Lett 211:33-36.
19. Floran B, Floran L, Sierra A, Aceves J. 1997. D2 receptor-mediated inhibition of GABA release by endogenous dopamine in the rat globus pallidus. Neurosci Lett 237:1-4.
20. Gerfen CR, Engber TM, Mahan LC, Susel Z, Chase TN, Monsma FJ, Sibley DR. 1990. D1 and D2 dopamine receptor regulated gene expression of striatonigral and striatopallidal neurons. Science 250:1429-1432.
21. Graybiel AM. 1990. Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci 13:244-254.
22. Graybiel AM. 1991. Basal ganglia - input, neural activity and relation to the cortex. Curr Opin Neurobiol 1:644-651.
23. Graybiel A, Moratalla R, Robertson HA. 1990. Amphetamine and cocaine induce drug-specific activation of the c-fos gene in the striosome-matrix compartments and limbic subdivisions of the striatum. Proc Natl Acad Sci USA 87:6912-6916.
24. Harper PS. 1996. Huntington's disease. London: W.B. Saunders Company Ltd.
25. Hebb MO, Robertson HA. 1997a. End-capped antisense oligodeoxynucleo-tides effectively inhibit gene expression in vivo and offer a low-toxicity alternative to fully modified phosphorothioate oligodeoxynucleotides. Mol Brain Res 47:223-228.
26. Hebb MO, Robertson HA. 1997b. Coordinate suppression of striatal ngfi-a and c-fos produces locomotor asymmetry and upregulation of IEGs in the globus pallidus. Mol Brain Res 48:97-106.
27. Hebb MO, Robertson HA. 1999a. Synergistic influences of the striatum and the globus pallidus on postural and locomotor control. Neuroscience 90:413-421.
28. Hebb MO, Robertson HA. 1999b. Alterations of neuronal activity in the superior colliculus of rotating animals. Neuroscience 90:423-432.
29. Heilig M, Engel J, Soderpalm B. 1993. C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. Eur J Pharmacol 236:339-340.
30. Hooper M, Chiasson B, Robertson H. 1994. Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of Fos and produces a behavioral effect. Neuroscience 63:917-924.
31. Hutchinson WD, Levy R, Dostrovsky JO, Lozano AM, Lang AE. 1997. Effects of apomorphine on globus pallidus neurons in parkinsonian patients. Ann Neurol 42:767-775.
32. Jimenez-Castellanos J, Reinoso-Suarez F. 1985. Topographical organization of the afferent connections of the principal ventromedial thalamic nucleus in the cat. J Comp Neurol 236:297-314.
33. Jones BE, Yang T. 1985. The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat. J Comp Neurol 242:56-92.
34. Kebabian JW, Calne DB. 1979. Multiple receptors for dopamine. Nature 277:93-96.
35. Kennard C, Lueck CJ. 1989. Oculomotor abnormalities in diseases of the basal ganglia. Rev Neurol Paris 145:587-595.
36. Lannes B, Micheletti G. 1997. Sensitization of the striatal dopaminergic system induced by chronic administration of a glutamate antagonist in the rat. Neurosci Biobehav Rev 21:417-424.
37. Lee RG. 1987. Physiology of the basal ganglia and pathophysiology of Parkinson's disease. Can J Neurol Sci 14:373-380.
38. LeMoine C, Normad E, Guitteny AF, Fouque B, Teoule R, Bloch B. 1990. Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc Natl Acad Sci USA 87:230-234.
39. LeMoine C, Normad E, Bloch B. 1991. Phenotypical characterization of rat striatal neurons expressing the D1 dopamine receptor gene. Proc Natl Acad Sci USA 88:4205-4209.
40. Linden R, Perry VH. 1983. Massive retinotectal projections in rats. Brain Res 272:145-149.
41. 2+ mobilization in Xenopus oocytes. Proc Natl Acad Sci USA 87:2186-2200.
42. Morelli M. 1997. Dopamine/glutamate interaction as studied by combining turning behaviour and c-Fos expression. Neurosci Biobehav Rev 21:505-509.
43. Moriizumi T, Nakamura Y, Tokuno H, Kudo M, Kitao Y. 1988. Convergence of afferent fibers from the entopeduncular nucleus and the substantia nigra pars reticulata onto single neurons in the ventromedial thalamic nucleus: an electron microscope study in the cat. Neurosci Lett 95:125-129.
44. Nakamura T, Kanayama R, Sano R, Ohki M, Kimura Y, Aoyagi M, Koike Y. 1991. Quantitative analysis of ocular movements in Parkinson's disease. Acta Otolaryngol Stockholm 481(Suppl):559-562.
45. Ozer H, Ekinci AC, Starr MS. 1997. Dopamine D1-and D2-dependent catalepsy in the rat requires functional NMDA receptors in the corpus striatum, nucleus accumbens and substantia nigra pars reticulata. Brain Res 777:51-59.
46. Paxinos G, Watson C. 1997. The rat brain in stereotaxic coordinates. New York: Academic Press.
47. Redgrave P, Odekunle A, Dean P. 1986. Tectal cells of origin of predorsal bundle in rat: location and segregation from ipsilateral descending pathway. Exp Brain Res 63:279-293.
48. Redgrave P, Mitchell I, Dean P. 1987. Descending projections from the superior colliculus in the rat: a study using orthograde transport of wheatgerm-agglutinin conjugated horseradish peroxidase. Exp Brain Res 68:147-167.
49. Robertson GS, Robertson HA. 1987. D1 and D2 dopamine agonist synergism: separate sites of action. Trends Pharmacol Sci. 8:295-299.
50. 1-dopamine receptor agonists selectively activate striatal c-fos independent of rotational behavior. Brain Res 503:346-349.
51. Sagar S, Sharp F, Curran T. 1988. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 240:1328-1331.
52. Sahibzada N, Dean P, Redgrave P. 1986. Movements resembling orientation or avoidance elicited by electrical stimulation of the superior colliculus in rats. J Neurosci 6:723-733.
53. Schwarting RK, Huston JP. 1996. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Progr Neurobiol 50:275-331.
54. Shammah-Lagnado SJ, Negrao N, Silva BA, Ricardo JA. 1987. Afferent connections of the nuclei reticularis pontis oralis and caudalis: a horseradish peroxidase study in the rat. Neuroscience 20:961-989.
55. Shibasaki H, Tsuji S, Kuroiwa Y. 1979. Oculomotor abnormalities in Parkinson's disease. Arch Neurol 36:360-364.
56. Sommer W, Bjelke B, Ganten D, Fuxe K. 1993. Antisense oligonucleotide to c-fos induces ipsilateral rotational behavior to d-amphetamine. Neuroreport 5:277-280.
57. Sommer W, Rimondini R, O'Connor W, Hansson AC, Ungerstedt U, Fuxe K. 1996. Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal γ-aminobutyric acid transmission in the conscious rat. Proc Natl Acad Sci USA 93:14134-14139.
58. Stoof JC, Kebabian JW. 1981. Opposing roles for D1 and D2 dopamine receptors in efflux of cyclic AMP from rat neostriatum. Nature 294:366-368.
59. Storey E, Beal MF. 1993. Neurochemical substrates of rigidity and chorea in Huntington's disease. Brain 116:1201-1222.
60. Ungerstedt U. 1968. 6-Hydroxydopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 5:107-110.
61. van der Kooy D, Carter DA. 1981. The organization of the efferent projections and striatal afferents of the entopeduncular nucleus and adjacent areas in the rat. Brain Res 211:15-36.
62. Vertes RP, Martin GF. 1988. Autoradiographic analysis of ascending projections from the pontine and mesencephalic reticular formation and the median raphe nucleus in the rat. J Comp Neurol 275:511-541.
63. Waldron HA, Gwyn DG. 1969. Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain. J Comp Neurol 137:143-154.
64. Westby GW, Keay KA, Redgrave P, Dean P, Bannister M. 1990. Output pathways from the rat superior colliculus mediating approach and avoidance have different sensory properties. Exp Brain Res 81:626-638.
65. Wurtz R, Albano J. 1980. Visual-motor function of the primate superior colliculus. Annu Rev Neurosci 3:189-226.