Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5- oxides

Journal of Medicinal Chemistry

Volumn 42, Issue 12, 1999, Pages 2218-2226

  Costanzo, Annarella ^a   Guerrini, Gabriella ^a   Ciciani, Giovanna ^a   Bruni, Fabrizio ^a   Selleri, Silvia ^a   Costa, Barbara ^b   Martini, Claudia ^b   Lucacchini, Antonio ^b   Malmberg Aiello, Petra ^a   Ipponi, Alessandra ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 (PYRROL 1 YL) 8 CHLOROPYRAZOLOL[5,1 C][1,2,4]BENZOTRIAZENE 5 OXIDE; 3 (THIEN 2 YL) 8 CHLOROPYRAZOLO[5,1 C][1,2,4]BENZOTIAZENE 5 OXIDE; 3 (THIEN 3 YL) 8 CHLOROPYRAZOLO[5,1 C][1,2,4]BENZOTRIAZENE OXIDE; ANXIOLYTIC AGENT; BENZODIAZEPINE RECEPTOR; DIAZEPAM; FLUMAZENIL; LIGAND; PENTETRAZOLE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; CATTLE; CEREBRAL CORTEX; CYCLIC N-OXIDES; LIGANDS; MALE; MICE; MUSCLE RELAXANTS, CENTRAL; RADIOLIGAND ASSAY; RECEPTORS, GABA-A; TRIAZINES;

EID: 0033578032     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm981126y     Document Type: Article

References (26)

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