B-cell commitment: Pax5 is the deciding factor

Current Biology

Volumn 9, Issue 24, 1999, Pages

  Enver, Tariq ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0033576667     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)80108-6     Document Type: Note

References (10)

1. Orkin SH, Zon LI: Genetics of erythropoiesis: induced mutations in mice and zebrafish. Annu Rev Genet 1997, 31:33-60.
2. Nutt SL, Heavey B, Rolink AG, Busslinger M: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999, 401:556-563.
3. Rolink AG, Nutt SL, Melchers F, Busslinger M: Long-term in vivo reconstitution of T-cell development by Pax5-defcient B-cell progenitors. Nature 1999, 401:603-606.
4. Morrison SJ, Shah NM, Andersen DJ: Regulatory mechanisms in stem cell biology. Cell 1997, 88:287-298.
5. Sieweke MH, Graf T: A transcription factor party during blood cell differentiation. Curr Opin Genet Dev 1998, 8:545-551.
6. Cory S: Wavering on commitment. Nature 1999, 401:538-539.
7. Nutt SL, Vambrie S, Steinlein P, Kozmik Z, Rolink A, Weith A, Busslinger M: Independent regulation of the two Pax5 alleles during B-cell development. Nat Genet 1999, 21:390-395.
8. Cook DL, Gerber AN, Tapscott SJ: Modelling stochastic gene expression: implications for haploinsufficiency. Proc Natl Acad Sci USA 1998, 95:15641-15646.
9. Hu M, Krause D, Greaves M, Sharkis S, Dexter M, Heyworth C, Enver T: Multilineage gene expression precedes commitment in the haematopoietic system. Genes Dev 1997, 11:774-785.
10. Enver T, Greaves M: Loops, lineages & leukaemia. Cell 1998, 94:9-12.