Ly-49C(B6) NK inhibitory receptor recognizes peptide-receptive H-2Kb

Journal of Immunology

Volumn 163, Issue 10, 1999, Pages 5319-5330

  Su, Ruey Chyi ^a   Kung, Sam Kam Pun ^a,d   Silver, Elizabeth T ^b   Lemieux, Suzanne ^c   Kane, Kevin P ^b   Miller, Richard G ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; CONCANAVALIN A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; CARRIER PROTEIN; H 2KB PROTEIN, MOUSE; H-2KB PROTEIN, MOUSE; H2 ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LECTIN; LY 49 ANTIGEN; LY ANTIGEN; LY-49 ANTIGEN; MEMBRANE PROTEIN; PEPTIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FEMALE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RECEPTOR BINDING; TARGET CELL; ANIMAL; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CROSS BREEDING; CYTOTOXICITY; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE ACTIVATION; LYMPHOKINE ACTIVATED KILLER CELL; METABOLISM; MOUSE; MOUSE MUTANT; NATURAL KILLER CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIBODY SPECIFICITY; ANTIGENS, LY; BINDING SITES, ANTIBODY; CARRIER PROTEINS; CELLS, CULTURED; CONCANAVALIN A; CROSSES, GENETIC; CYTOTOXICITY, IMMUNOLOGIC; H-2 ANTIGENS; IMMUNITY, NATURAL; KILLER CELLS, LYMPHOKINE-ACTIVATED; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NUDE; MICE, TRANSGENIC; PEPTIDES; RECEPTORS, IMMUNOLOGIC;

EID: 0033570772     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Yokoyama, Y. M. 1998. Natural killer cell receptors. Curr. Opin. Immunol. 10: 298.
2. Moretta, L., E. Ciccone, A. Moretta, P. Höglund, C. Ohlen, and K. Kärre. 1992. Allorecognition by NK cells: nonself or self. Immunol. Today 13:300.
3. Yokoyama, W. M., and W. E. Seaman. 1993. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Anna. Rev. Immunol. 11:613.
4. Lanier, L. L. 1998. Follow the leader: NK cell receptors for classical and non-classical MHC class I. Cell 92:705.
5. Lanier, L. L., and J. H. Phillips. 1996. Inhibitory MHC class I receptors on NK cells and T cells. Immunol. Today 17:86.
6. + IL-2-activated natural killer cells. Nature 358: 66.
7. Held, W., D. Cado, and D. H. Raulet. 1996. Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocornpatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. J. Exp. Med. 184:2037.
8. Brennan, J., D. Mager, W. Jefferies, and F. Takei. 1994. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J. Exp. Med. 180:2287.
9. Yu, Y. Y. L., T. George, J. R. Dorfman, J. Roland, V. Kumar, and M. Bennett. 1996. The role of Ly49A and 5E6 (Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts. Immunity 4:67.
10. Neefjes, J. J., L. Smith, M. Gehrmann, and H. L. Plöegh. 1992. The fate of the three subunits of major histocompatibility complex class I molecules. Eur. J. Immunol. 22:1609.
11. Ortiz-Navarrete, V., and G. J. Hämmerling. 1991. Surface appearance and instability of empty H-2 class I molecules under physiological conditions. Proc. Natl. Acad. Sci. USA 88:3594.
12. 2m. J. Immunol. 151:3082.
13. Day, P. M., F. Esquivel, J. Lukszo, J. R. Bennink, and J. W. Yewdell. 1995. Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules. Immunity 2:137.
14. Christinck, E. R., M. A. Luscher, B. H. Barber, and D. B. Williams. 1991. Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis. Nature 352:67.
15. Storkus, W. J., J. Alexander, J. A. Payne, P. Cresswell, and J. R. Dawson. 1989. The α1/α2 domains of class I HLA molecules confer resistance to natural killing. J. Immunol. 143:3853.
16. Storkus, W. J., R. D. Salter, J. Alexander, F. E. Ward, R. E. Ruiz, P. Cresswell, and J. R. Dawson. 1991. Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2. Proc. Natl. Acad. Sci. USA 88:5989.
17. d restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A. J. Immunol. 160: 5971.
18. Storkus, W. J., R. D. Salter, P. Cresswell, and J. R. Dawson. 1992. Peptide-induced modulation of target cell sensitivity to natural killing. J. Immunol. 149: 1185.
19. Chadwick, B. S., and R. G. Miller. 1992. Hybrid resistance in vitro: possible role of both class I MHC and self peptides in determining the level of target cell sensitivity. J. Immunol. 148:2307.
20. Chadwick, B. S., S. R. Sambhara, Y. Sasakura, and R. G. Miller. 1992. Effect of class I MHC binding peplides on recognition by natural killer cells. J. Immunol. 149:3150.
21. Su, R. C., S. K. Rung, J. Gariepy, B. H. Barber, and R. G. Miller. 1998. NK cells can recognize different forms of class I MHC. J. Immunol. 161:755.
22. Correa. L., and D. H. Raulet. 1995. Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity 2:61.
23. Orihuela, M., D. H. Margulies, and W. M. Yokoyama. 1996. The natural killer cell receptor Ly49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand. Proc. Natl. Acad. Sci. USA 93:11792.
24. Brennan, J., S. Lemieux, J. D. Freeman, D. L. Mager, and F. Takei. 1996. Heterogeneity among Ly-49C natural killer (NK) cells: characterization of highly related receptors with differing functions and expression patterns. J. Exp. Med. 184:2085.
25. Tanchot, C., F. A. Lemonnier, B. Perarnau, A. A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276:2057.
26. 2m double knockout mice. J. Exp. Med. 185:2043.
27. Kung, S. K., R. C. Su, J. J. Graham, J. W. Chamberlain, and R. G. Miller. 1998. NK cells from human MHC class I (HLA-B) transgenic mice do not mediate hybrid resistance killing against parental nontransgenic cells. J. Immunol. 60:674.
28. Karasuyama, H., H. Tohyama, and T. Tada. 1989. Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene. J. Exp. Med. 169:13.
29. Rötzschke, O., K. Falk, S. Stevanovie, G. Jung, P. Walden, and H.-G. Rammensee. 1991. Exact prediction of a natural T cell epitope. Eur. J. Immunol. 21:2891.
30. Rammensee, H.-G., K. Falk, and O. Rötzschke. 1993. Peptides naturally presented by MHC class I molecules. Annu. Rev. Immunol. 11:213.
31. Rötzschke, O., K. Falk, K. Deres, H. Schild, M. Norda, J. Metzger, G. Jung, and H.-G. Rammensee. 1990. Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature 348:252.
32. Shiral, M., C. D. Pendleton, and J. A. Berzofsky. 1992. Broad recognition of cylotoxic T cell epitopes from the HIV-1 envelope protein with multiple class I histocompatibility molecules. J. Immunol. 148:1657.
33. d-restricted antigenic peptides share a simple binding motif. J. Exp. Med. 174:603.
34. 1 antiparent killer in vitro. J. Immunol. 154:1624.
35. Kozlowski, S., M. Corr, T. Takeshita, L. F. Boyd, C. D. Pendleton, R. N. Germain, J. A. Berzofsky, and D. H. Margulies. 1992. Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp 160 peptide for presentation by major histocompatibility complex class 1 molecules. J. Exp. Med. 175:1417.
36. Porgador, A., J. W. Yewdell, Y. Deng, J. R. Bennink, and R. N. Germain. 1997. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 6:715.
37. Roland, J., and P. A. Cazenave. 1992. Ly-49 antigen defined an αβ TCR population in i-IEL with an extrathymic maturation. Int. Immunol. 4:699.
38. b heavy chains. Mol. Immunol. 27:169.
39. Deng, Y., J. Gibbs, I. Bacik, A. Porgador, J. Copeman, P. Lehner, B. Ortmann, P. Cresswell, J. R. Bennink, and J. W. Yewdell. 1998. Assembly of MHC class I molecules with biosynthesized endoplasmic reticulum-targeted peptides is inefficient in insect cells and can be enhanced by protease inhibitors. J. Immunol. 161:1677.
40. b mutants. Immunogenetics 12:183.
41. b-restricted ovalbumin peptide and an assessment of the predictive power of MHC-binding motifs. Eur. J. Immunol. 22:2663.
42. Jameson, S. C., F. R. Carbone, and M. J. Bevan. 1993. Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells. J. Exp. Med. 177:1541.
43. b molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc. Natl. Acad. Sci. USA 89:8403.
44. b. Science 257:919.
45. Gosselin, P., Y. Lusignan, J. Brennan, F. Takei, and S. Lemieux. 1997. The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles. Int. Immunol. 9:533.
46. Stoneman, E. R., M. Bennett, J. An, K. A. Chesnut, E. K. Wakeland, J. B. Scheerer, M. J. Siciliano, V. Kumar, and P. A. Mathew. 1995. Cloning and characterization of 5E6(Ly49C), a receptor molecule expressed on a subset of murine natural killer cells. J. Exp. Med. 182:305.
47. Kane, K. P. 1994. Ly49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. J. Exp. Med. 179:1011.
48. Brennan, J., G. Mahon, D. L. Mager, W. A. Jefferies, and F. Takei. 1996. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. J. Exp. Med. 183:1553.
49. McQueen, K. L., J. D. Freeman, F. Takei, and D. L. Mager. 1998. Localization of five new Ly49 genes, including three closely related to Ly49c. Immunogenetics 48:174.
50. Held, W., and B. Kunz. 1998. An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire. Eur. J. Immunol. 28:2407.
51. Vance, R. E., J. R. Kraft, J. D. Altman, P. E. Jensen, and D. H. Raulet. 1998. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major hislocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 188: 1841.
52. Bluestone, J. A., S. Jameson, S. Miller, and R. D. Dick. 1992. Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition. J. Exp. Med. 176:1757.
53. Elliott, T., V. Cerundolo, J. Elvin, and A. Townsend. 1991. Peptide-induced conformational change of the class I heavy chain. Nature 351:402.
54. Catipovic, B., J. Dal Porto, M. Mage, T. E. Johansen, and J. P. Schneck. 1992. Major histocompatibility complex conformational epitopes are peptide specific. J. Exp. Med. 176:1611.
55. Catipovic, B., G. Talluri, J. Oh, T. Wei, X. M. Su, T. E. Johansen, M. Edidin, and J. P. Schneck. 1994. Analysis of the structure of empty and peptide-loaded major histocompatibility complex molecules at the cell surface. J. Exp. Med. 180:1753.
56. d MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition. Immunity 9:199.
57. Townsend, A., and H. Bodmer. 1989. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:601.