Molecular cloning and functional characterization of a snake venom metalloprotease

European Journal of Biochemistry

Volumn 263, Issue 2, 1999, Pages 526-533

  Jeon, Ok Hee ^a   Kim, Doo Sik ^a  

^a Yonsei University   (South Korea)

Author keywords

Disintegrin; Enzyme processing; Metalloprotease; Protein refolding

Indexed keywords

COMPLEMENTARY DNA; DISINTEGRIN; METALLOPROTEINASE; SCLEROPROTEIN; SNAKE VENOM;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PROCESSING; SEQUENCE ANALYSIS; SNAKE; THROMBOCYTE AGGREGATION INHIBITION;

AMINO ACID SEQUENCE; BASE SEQUENCE; EXTRACELLULAR MATRIX PROTEINS; FIBRINOGEN; GENE LIBRARY; HUMANS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PLATELET AGGREGATION INHIBITORS; PROTEIN FOLDING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SNAKE VENOMS;

AGKISTRODON; AMPHIBIA; ESCHERICHIA COLI; GLOYDIUS BLOMHOFFI BREVICAUDUS; GLOYDIUS HALYS; REPTILIA; SERPENTES;

EID: 0033565573     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00525.x     Document Type: Article

References (33)

1. 1. Selistre, H.S., Dulce, H.F. & Ownby, C.L. (1997) Analysis of a cDNA sequence encoding a novel member of the snake venom metalloproteases, disintegrin-like, cysteine-rich (MDC) protein family from Agkistrodon contortrix laticinctus. Biochim. Biophys. Acta. 1342, 109-115.
2. 2. Baravoma, E.N., Shannon, J.D., Bjarnason, J.B. & Fox, J.W. (1989) Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases. Arch. Biochem. Biophys. 275, 63-71.
3. 3. Itoh, M., Madusa, K., Ito, Y., Akizawa, T., Yoshioka, M., Imai, K., Odaka, Y., Sato, H. & Seiki, M. (1996) Purification and refolding of recombinant human proMMP-7 (pro-Matrilysin) expressed in Escherichia coli and its characterization. J. Biochem. 119, 667-673.
4. 4. Selistre, H.S. & Ownby, C.L. (1995) Molecular cloning and sequence analysis of cDNAs for metalloproteinases from broad-banded copperhead Agkistrodon contortrix laticinctus. Arch. Biochem. Biophys. 320, 141-148.
5. 5. Zhou, Q., Smith, J.B. & Grossman, M.H. (1995) Molecular cloning and expression of catrocollastalin, a snake-venom protein from Crotalus atrox (western diamond rattlesnake) which inhibits platelet adhesion to collagen. Biochem. J. 307, 411-417.
6. 6. Paine, M.J.I., Desmond, H.P., Theakston, R.D.J. & Crampton, J.M. (1992) Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararrhagin, from Bothrops jararaca venom. J. Biol. Chem. 267, 22869-22876.
7. 7. Takeya, H., Onikuri, A., Nikai, T., Sugihara, H. & Iwanaga, S. (1990) Primary structure of a hemorrhagic metalloproteinase, HT-2, isolated from the venom of Crotalus ruber ruber. J. Biochem. 108, 711-719.
8. 8. Hite, L.A., Jia, L.G., Bjarnason, J.B. & Fox, J.W. (1994) cDNA sequences for four snake venom metalloprotease: structure, classificaion, and their relationship to mammalian reproductive proteins. Arch. Biochem. Biophys. 308, 182-191.
9. 9. Chao, B.H., Jakubowski, J.A., Savage, B., Chow, E.P., Marzec, U.M., Harker, L.A. & Maraganore, J.M. (1989) Agkistrodon piscivorus piscivorus platelet aggregation inhibitor: a potent inhibitor of platelet activation. Proc. Natl Acad. Sci. USA 86, 8050-8054.
10. 10. Haung, T.F., Holt, J.C., Kirby, I.P. & Hiewiaroski, S. (1991) Trigramin: primary structure and its inhibition of von Willebrand factor binding to glycoprotein IIb/IIIa complex on human platelets. Biochemistry 28, 661-666.
11. 11. Kang, I.C., Chung, K.H., Lee, S.J., Yun, Y.D., Moon, H.M. & Kim, D.S. (1998) Purification and molecular cloning of a platelet aggregation inhibitor from the snake (Agkistrodon halys brevicaudus) venom. Thromb. Res. 91, 65-73.
12. 12. Takeya, H., Nishida, S., Nishino, N., Makinose, Y., Omori-Satoh, T., Nikai, H., Sugihara, H. & Iwanaga, S. (1993) Primary structure of platelet aggregation inhibitors (disintegrins) autoproteolytically released from snake venom hemorrhgic metalloproteinase and new fluorogenic peptide substrates for these enzymes. J. Biochem. 113, 473-483.
13. 13. Wolfsberg, T.G., Bazan, J.F., Blobel, C.P., Myles, D.G., Primakoff, P. & White, J.M. (1993) The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: Structural, functional, and evolutionary implications. Proc. Natl Acad. Sci. USA 90, 10783-10787.
14. 14. Moss, M.L., Jim, S.L., Milla, M.E., Bickett, D.M., Burkhart, W., Carter, H.L., Chen, W.J., Clay, W.C., Didsbury, J.R., Hassler, D., Hoffman, C.R., Kost, T.A., Lambert, M.U., Leesnitzer, M.A., McCauley, P., McGreeham, G., Mitchell, J., Moyer, M., Pahel, G., Rocque, W., Overton, L.K., Schoenen, F., Seuton, T., Su, J.L., Warner, J., Willard, D. & Becherer, J.D. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumor-necrosis factor-α. Nature 385, 733-736.
15. 15. Kratzschmar, J., Lum, L. & Blobel, C.P. (1996) Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. J. Biol. Chem. 271, 4593-4596.
16. 16. Weskamp, G., Kratzschmar, J., Reid, M.S. & Blobel, C.P. (1996) MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domain. J. Cell Biol. 132, 717-726.
17. 17. Paine, M.J.I., Moura-da-sina, A.M., Theakston, R.D.G. & Crampton, J.M. (1994) Cloning of metalloprotease genes in the carpet viper (Echis pyramidum leakeyi). Eur. J. Biochem. 224, 483-488.
18. 18. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) Molecular Cloning: a Labatory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, New York.
19. 19. Shannon, J.D., Baramova, E.N., Bjarnason, J., B. & Fox, J.W. (1989) Amino acid Sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin. J. Biol. Chem. 264, 11575-11583.
20. 20. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227, 680-685.
21. 21. Grams, F., Huber, R., Kress, L.F., Moroder, L. & Bode, W. (1993) Activation of snake venom metalloproteases by a cysteine switch-like mechanism. FEBS Lett. 335, 76-80.
22. 2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis. J. Biochem. 106, 151-157.
23. 23. Hite, L.A., Shannon, J.D., Bjarnason, J.B. & Fox, J.W. (1992) Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: Evidence for signal, zymogen, and disintegrin-like structures. Biochemistry 31, 6203-6211.
24. 24. Shebuski, R.J., Ramjit, D.R., Bencen, G.H. & Polokoff, M.A. (1989) Characterization and platelet inhibitory activity of bitistatin, a potent arginine-glycine-aspartic acid-containing peptide from the venom of the viper Bitis aretans. J. Biol. Chem. 264, 21550-21556.
25. 25. Scarborough, R.M., Rose, J.W., Hsu, M.A., Phillips, D.R., Fried, V.A., Campbell, M., Nannizzi, L. & Charo. F. (1991) Barbourin: a gpIIb-IIIa-specific integrin antagonist from the venom of Sistrurus M. barbouri. J. Biol. Chem. 266, 9359-9362.
26. 26. Siigur, E., Aaspollu, A., Tu, A.T. & Siigur, J. (1996) cDNA cloning and deduced amino acid sequence of fibrinolytic enzyme (lebetase) from Vipera lebetina snake venom. Biochem. Biophys. Res. Commun. 224, 229-236.
27. 27. Maeda, M., Satoh, S., Suzuki, S., Niwa, M., Itoh, N. & Yamashina, I. (1991) Expression of cDNA for batroxobin, a thrombin-like snake venom enzyme. J. Biochem. (Tokyo) 109, 632-637.
28. 28. Tryggvason, K., Hoyhtya, M. & Salo, T. (1987) Proteolytic degradation of extracellular matrix in tumor invasion. Biochim. Biophys. Acta. 907, 191-217.
29. 29. Kamiguti, A.S., Slupsky, J.R., Zuzel, M. & Hay, C.R.M. (1994) Properties of fibrinogen cleaved by jararrhagin, a metalloproteinase from the venom of Bothrops jararaca. Thromb. Haemost. 72, 244-249.
30. 30. Haralson, M.A. & Hassell, J.R. (1995) Extracellular Matrix: A Practical Approach. IRL, Oxford University, New York.
31. 31. Kamiguti, A.S., Hay, C.R.M. & Zuzel, M. (1996) Inhibition of collagen-induced platelet aggregation as the result of cleavage of α2β1-integrin by the snake venom metalloprotease jararhagin. Biochem. J. 320, 635-641.
32. 32. Hynes, R.O. (1987) Integrins: a family of cell surface receptors. Cell 48, 549-554.
33. 33. Savage, B. & Rugger, Z.M. (1991) Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets. J. Biol. Chem. 266, 11227-11233.