Dimerization of the p185(neu) transmembrane domain is necessary but not sufficient for transformation

Oncogene

Volumn 14, Issue 6, 1997, Pages 687-696

  Burke, Christine L ^a   Lemmon, Mark A ^c   Coren, Barbara A ^a   Engelman, Donald M ^b   Stern, David F ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Dimerization; neu HER2 erB 2; Receptor tyrosine kinase; Transmembrane domain

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTAMIC ACID; GLYCINE; GLYCOPHORIN A; MEMBRANE PROTEIN; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; VALINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLYCOPHORIN; HYBRID PROTEIN; TYROSINE;

ALLELE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL TRANSFORMATION; CHIMERA; CONTROLLED STUDY; DIMERIZATION; DNA TRANSFECTION; GENE MUTATION; HORMONAL REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTO ONCOGENE; SIGNAL TRANSDUCTION; ANIMAL; BINDING SITE; CELL STRAIN COS1; GENETIC TRANSFORMATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COS CELLS; DIMERIZATION; GLYCOPHORIN; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSFORMATION, GENETIC; TYROSINE;

EID: 0030614530     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1200873     Document Type: Article

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